FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3004892587> ?p ?o ?g. }

• W3004892587 abstract "Abstract IL-17A is an important pro-inflammatory cytokine involved in the inflammatory response in chronic obstructive pulmonary disease (COPD). To evaluate the role played by single nucleotide polymorphisms of IL17A and protein levels in susceptibility to COPD, 1,807 subjects were included in a case-control study; 436 had COPD related to tobacco smoking (COPD-S) and 190 had COPD related to biomass burning (COPD-BB). Six hundred fifty-seven smokers without COPD (SWOC) and 183 biomass burning-exposed subjects (BBES) served as the respective control groups. The CC genotype and C allele of rs8193036 were associated with COPD (COPD-S vs . SWOC: p < 0.05; OR = 3.01, and OR = 1.28, respectively), as well as a recessive model (p < 0.01; OR = 2.91). Significant differences in serum levels were identified between COPD-S vs . SWOC, COPD-S vs . COPD-BB, and SWOC vs . BBES (p < 0.01). By comparing genotypes in the COPD-BB group TT vs . CC and TC vs . CC (p < 0.05), we found lower levels for the CC genotype. Logistic regression analysis by co-variables was performed, keeping the associations between COPD-S vs . SWOC with both polymorphisms evaluated (p < 0.05), as well as in COPD-BB vs . BBES but with a reduced risk of exacerbation (p < 0.05). In conclusion, polymorphisms in IL17A are associated with COPD. Serum levels of IL-17A were higher in smokers with and without COPD." @default.
• W3004892587 created "2020-02-14" @default.
• W3004892587 creator A5007262185 @default.
• W3004892587 creator A5011241778 @default.
• W3004892587 creator A5015971204 @default.
• W3004892587 creator A5018189324 @default.
• W3004892587 creator A5020143656 @default.
• W3004892587 creator A5043725900 @default.
• W3004892587 creator A5049697949 @default.
• W3004892587 creator A5056550985 @default.
• W3004892587 creator A5068626256 @default.
• W3004892587 creator A5078953685 @default.
• W3004892587 date "2020-01-21" @default.
• W3004892587 modified "2023-09-29" @default.
• W3004892587 title "Genetic variants in IL17A and serum levels of IL-17A are associated with COPD related to tobacco smoking and biomass burning" @default.
• W3004892587 cites W1034171487 @default.
• W3004892587 cites W1888766653 @default.
• W3004892587 cites W1891992202 @default.
• W3004892587 cites W1950625533 @default.
• W3004892587 cites W1953402117 @default.
• W3004892587 cites W1970194636 @default.
• W3004892587 cites W1978855332 @default.
• W3004892587 cites W2002726093 @default.
• W3004892587 cites W2009155901 @default.
• W3004892587 cites W2012519534 @default.
• W3004892587 cites W2020151713 @default.
• W3004892587 cites W2034355357 @default.
• W3004892587 cites W2042495092 @default.
• W3004892587 cites W2044433987 @default.
• W3004892587 cites W2052219561 @default.
• W3004892587 cites W2097734747 @default.
• W3004892587 cites W2103648842 @default.
• W3004892587 cites W2112686581 @default.
• W3004892587 cites W2117145322 @default.
• W3004892587 cites W2117837864 @default.
• W3004892587 cites W2122590281 @default.
• W3004892587 cites W2122790962 @default.
• W3004892587 cites W2123547619 @default.
• W3004892587 cites W2129468544 @default.
• W3004892587 cites W2131963153 @default.
• W3004892587 cites W2132128923 @default.
• W3004892587 cites W2142566654 @default.
• W3004892587 cites W2152230693 @default.
• W3004892587 cites W2153838261 @default.
• W3004892587 cites W2156645716 @default.
• W3004892587 cites W2161633633 @default.
• W3004892587 cites W2169756967 @default.
• W3004892587 cites W2315362038 @default.
• W3004892587 cites W2340073352 @default.
• W3004892587 cites W2406455267 @default.
• W3004892587 cites W2557122553 @default.
• W3004892587 cites W2580050890 @default.
• W3004892587 cites W2583265473 @default.
• W3004892587 cites W2587402252 @default.
• W3004892587 cites W2608737345 @default.
• W3004892587 cites W2643696376 @default.
• W3004892587 cites W2724609343 @default.
• W3004892587 cites W2752659577 @default.
• W3004892587 cites W2761511671 @default.
• W3004892587 cites W2786392891 @default.
• W3004892587 cites W2790776977 @default.
• W3004892587 cites W2793861737 @default.
• W3004892587 cites W2804674919 @default.
• W3004892587 cites W2886165084 @default.
• W3004892587 cites W2899757224 @default.
• W3004892587 doi "https://doi.org/10.1038/s41598-020-57606-6" @default.
• W3004892587 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6972744" @default.
• W3004892587 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31964947" @default.
• W3004892587 hasPublicationYear "2020" @default.
• W3004892587 type Work @default.
• W3004892587 sameAs 3004892587 @default.
• W3004892587 citedByCount "9" @default.
• W3004892587 countsByYear W30048925872020 @default.
• W3004892587 countsByYear W30048925872021 @default.
• W3004892587 countsByYear W30048925872022 @default.
• W3004892587 countsByYear W30048925872023 @default.
• W3004892587 crossrefType "journal-article" @default.
• W3004892587 hasAuthorship W3004892587A5007262185 @default.
• W3004892587 hasAuthorship W3004892587A5011241778 @default.
• W3004892587 hasAuthorship W3004892587A5015971204 @default.
• W3004892587 hasAuthorship W3004892587A5018189324 @default.
• W3004892587 hasAuthorship W3004892587A5020143656 @default.
• W3004892587 hasAuthorship W3004892587A5043725900 @default.
• W3004892587 hasAuthorship W3004892587A5049697949 @default.
• W3004892587 hasAuthorship W3004892587A5056550985 @default.
• W3004892587 hasAuthorship W3004892587A5068626256 @default.
• W3004892587 hasAuthorship W3004892587A5078953685 @default.
• W3004892587 hasBestOaLocation W30048925871 @default.
• W3004892587 hasConcept C104317684 @default.
• W3004892587 hasConcept C126322002 @default.
• W3004892587 hasConcept C135763542 @default.
• W3004892587 hasConcept C151956035 @default.
• W3004892587 hasConcept C153209595 @default.
• W3004892587 hasConcept C180754005 @default.
• W3004892587 hasConcept C203014093 @default.
• W3004892587 hasConcept C2776780178 @default.
• W3004892587 hasConcept C2777014857 @default.
• W3004892587 hasConcept C54355233 @default.
• W3004892587 hasConcept C71924100 @default.
• W3004892587 hasConcept C86803240 @default.

• next