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- W3005081032 endingPage "100974" @default.
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- W3005081032 abstract "A novel pH-sensitive block polymer poly (propylene carbonate)-b-poly (acrylic acid) (PPC-b-PAA) was successfully synthesized by the free radical polymerization and hydrolysis reaction. The polymer structure was characterized with 1H MNR and 13 C NMR. pH-Responsive property and the critical micelle concentration of PPC-b-PPA were studied in detail. The size of nanoparticles at different pH were demonstrated by dynamic light scattering, which the size expanded dramatically with an increase alkaline concentration at 2.5-7.5. Chlorpyrifos (CHP) loaded PPC-b-PAA nanoparticles were synthesized by diffusion dialysis method. PPC-b-PAA nanoparticles has high drug loading efficiency and drug loading content, good stability. With the increasing of acrylic acid dosage, the CHP release rate was decreased in PBS. PPC-b-PAA nanoparticles has special effect for drug release." @default.
- W3005081032 created "2020-02-14" @default.
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- W3005081032 date "2020-09-01" @default.
- W3005081032 modified "2023-10-12" @default.
- W3005081032 title "Synthesis and characterization of pH-sensitive block polymer poly (propylene carbonate)-b-poly (acrylic acid) for sustained chlorpyrifos release" @default.
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- W3005081032 doi "https://doi.org/10.1016/j.mtcomm.2020.100974" @default.
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