FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3005153670> ?p ?o ?g. }

• W3005153670 endingPage "225" @default.
• W3005153670 startingPage "225" @default.
• W3005153670 abstract "The search for novel bioactive metabolites continues to be of much importance around the world for pharmaceutical, agricultural, and industrial applications. Actinobacteria constitute one of the extremely interesting groups of microorganisms widely used as important biological contributors for a wide range of novel secondary metabolites. This study focused on the assessment of antimicrobial and antioxidant activity of crude extracts of actinobacterial strains. Western Ghats of India represents unique regions of biologically diverse areas called “hot spots”. A total of 32 isolates were obtained from soil samples of different forest locations of Bisle Ghat and Virjapet situated in Western Ghats of Karnataka, India. The isolates were identified as species of Streptomyces, Nocardiopsis, and Nocardioides by cultural, morphological, and molecular studies. Based on preliminary screening, seven isolates were chosen for metabolites extraction and to determine antimicrobial activity qualitatively (disc diffusion method) and quantitatively (micro dilution method) and scavenging activity against DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radicals. Crude extracts of all seven isolates exhibited fairly strong antibacterial activity towards MRSA strains (MRSA ATCC 33591, MRSA ATCC NR-46071, and MRSA ATCC 46171) with MIC varying from 15.62 to 125 μg/mL, whereas showed less inhibition potential towards Gram-negative bacteria Salmonella typhi (ATCC 25241) and Escherichia coli (ATCC 11775) with MIC of 125–500 μg/mL. The isolates namely S1A, SS5, SCA35, and SCA 11 inhibited Fusarium moniliforme (MTCC 6576) to a maximum extent with MIC ranging from 62.5 to 250 μg/mL. Crude extract of SCA 11 and SCA 13 exhibited potent scavenging activities against DPPH and ABTS radicals. The results from this study suggest that actinobacterial strains of Western Ghats are an excellent source of natural antimicrobial and antioxidant compounds. Further research investigations on purification, recovery, and structural characterization of the active compounds are to be carried out." @default.
• W3005153670 created "2020-02-14" @default.
• W3005153670 creator A5010720523 @default.
• W3005153670 creator A5017995404 @default.
• W3005153670 creator A5040844533 @default.
• W3005153670 creator A5090457900 @default.
• W3005153670 date "2020-02-07" @default.
• W3005153670 modified "2023-10-11" @default.
• W3005153670 title "Diversity and Bioactive Potential of Actinobacteria from Unexplored Regions of Western Ghats, India" @default.
• W3005153670 cites W1921392382 @default.
• W3005153670 cites W1961797891 @default.
• W3005153670 cites W1967745712 @default.
• W3005153670 cites W1985339859 @default.
• W3005153670 cites W1986038186 @default.
• W3005153670 cites W1990119536 @default.
• W3005153670 cites W2020289560 @default.
• W3005153670 cites W2020621217 @default.
• W3005153670 cites W2029215004 @default.
• W3005153670 cites W2034149228 @default.
• W3005153670 cites W2044627978 @default.
• W3005153670 cites W2046364391 @default.
• W3005153670 cites W2060555552 @default.
• W3005153670 cites W2068287003 @default.
• W3005153670 cites W2084818162 @default.
• W3005153670 cites W2091558637 @default.
• W3005153670 cites W2099838379 @default.
• W3005153670 cites W2105731956 @default.
• W3005153670 cites W2125066910 @default.
• W3005153670 cites W2132303900 @default.
• W3005153670 cites W2142613971 @default.
• W3005153670 cites W2169633254 @default.
• W3005153670 cites W2239292882 @default.
• W3005153670 cites W2282124923 @default.
• W3005153670 cites W2323872145 @default.
• W3005153670 cites W2328424302 @default.
• W3005153670 cites W2433419944 @default.
• W3005153670 cites W2751528963 @default.
• W3005153670 cites W2778569380 @default.
• W3005153670 cites W2806391042 @default.
• W3005153670 cites W2884202646 @default.
• W3005153670 cites W2898358684 @default.
• W3005153670 cites W2979450945 @default.
• W3005153670 doi "https://doi.org/10.3390/microorganisms8020225" @default.
• W3005153670 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7074718" @default.
• W3005153670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32046111" @default.
• W3005153670 hasPublicationYear "2020" @default.
• W3005153670 type Work @default.
• W3005153670 sameAs 3005153670 @default.
• W3005153670 citedByCount "21" @default.
• W3005153670 countsByYear W30051536702020 @default.
• W3005153670 countsByYear W30051536702021 @default.
• W3005153670 countsByYear W30051536702022 @default.
• W3005153670 countsByYear W30051536702023 @default.
• W3005153670 crossrefType "journal-article" @default.
• W3005153670 hasAuthorship W3005153670A5010720523 @default.
• W3005153670 hasAuthorship W3005153670A5017995404 @default.
• W3005153670 hasAuthorship W3005153670A5040844533 @default.
• W3005153670 hasAuthorship W3005153670A5090457900 @default.
• W3005153670 hasBestOaLocation W30051536701 @default.
• W3005153670 hasConcept C11636898 @default.
• W3005153670 hasConcept C185592680 @default.
• W3005153670 hasConcept C2778004101 @default.
• W3005153670 hasConcept C2778169975 @default.
• W3005153670 hasConcept C2780104969 @default.
• W3005153670 hasConcept C2781031786 @default.
• W3005153670 hasConcept C2781401929 @default.
• W3005153670 hasConcept C31903555 @default.
• W3005153670 hasConcept C42062724 @default.
• W3005153670 hasConcept C4937899 @default.
• W3005153670 hasConcept C523546767 @default.
• W3005153670 hasConcept C54355233 @default.
• W3005153670 hasConcept C55493867 @default.
• W3005153670 hasConcept C556039675 @default.
• W3005153670 hasConcept C71924100 @default.
• W3005153670 hasConcept C86803240 @default.
• W3005153670 hasConcept C89423630 @default.
• W3005153670 hasConceptScore W3005153670C11636898 @default.
• W3005153670 hasConceptScore W3005153670C185592680 @default.
• W3005153670 hasConceptScore W3005153670C2778004101 @default.
• W3005153670 hasConceptScore W3005153670C2778169975 @default.
• W3005153670 hasConceptScore W3005153670C2780104969 @default.
• W3005153670 hasConceptScore W3005153670C2781031786 @default.
• W3005153670 hasConceptScore W3005153670C2781401929 @default.
• W3005153670 hasConceptScore W3005153670C31903555 @default.
• W3005153670 hasConceptScore W3005153670C42062724 @default.
• W3005153670 hasConceptScore W3005153670C4937899 @default.
• W3005153670 hasConceptScore W3005153670C523546767 @default.
• W3005153670 hasConceptScore W3005153670C54355233 @default.
• W3005153670 hasConceptScore W3005153670C55493867 @default.
• W3005153670 hasConceptScore W3005153670C556039675 @default.
• W3005153670 hasConceptScore W3005153670C71924100 @default.
• W3005153670 hasConceptScore W3005153670C86803240 @default.
• W3005153670 hasConceptScore W3005153670C89423630 @default.
• W3005153670 hasIssue "2" @default.
• W3005153670 hasLocation W30051536701 @default.
• W3005153670 hasLocation W30051536702 @default.
• W3005153670 hasLocation W30051536703 @default.
• W3005153670 hasLocation W30051536704 @default.

• next