Matches in SemOpenAlex for { <https://semopenalex.org/work/W3005234850> ?p ?o ?g. }
- W3005234850 abstract "Abstract Preferentially expressed antigen in melanoma (PRAME), which belongs to the cancer/testis antigen (CTA) gene family, plays a pivotal role in multiple cellular processes and immunotherapy response in human cancers. PRAME is highly expressed in different types of cancers and is involved in cell proliferation, apoptosis, differentiation and metastasis as well as the outcomes of patients with cancer. In this review article, we discuss the potential roles and physiological functions of PRAME in various types of cancers. Moreover, this review highlights immunotherapeutic strategies that target PRAME in human malignancies. Therefore, the modulation of PRAME might be useful for the treatment of patients with cancer." @default.
- W3005234850 created "2020-02-14" @default.
- W3005234850 creator A5003159043 @default.
- W3005234850 creator A5032673072 @default.
- W3005234850 creator A5037677450 @default.
- W3005234850 creator A5043362352 @default.
- W3005234850 creator A5051242689 @default.
- W3005234850 date "2020-02-05" @default.
- W3005234850 modified "2023-10-14" @default.
- W3005234850 title "The role of the cancer testis antigen PRAME in tumorigenesis and immunotherapy in human cancer" @default.
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