Matches in SemOpenAlex for { <https://semopenalex.org/work/W3005397796> ?p ?o ?g. }
- W3005397796 endingPage "621" @default.
- W3005397796 startingPage "613" @default.
- W3005397796 abstract "Abstract Background Although vitamin D deficiency is associated with several inflammatory conditions, there have been few studies on the effects of vitamin D supplementation on markers of oxidative stress (OS) and inflammation. The aim of the current study was to evaluate the effects of high-dose vitamin D supplementation on heat shock protein 27 antibody (anti-Hsp27) titers in adolescent girls. Methods Five hundred and fifty adolescent girls received vitamin D3 at a dose of 50,000 IU/week for 9 weeks. Demographic, clinical and biochemical markers including serum fasting blood glucose (FBG), lipid profile and anti-Hsp27 titers as well as hematological parameters including white blood cell (WBC) count and red blood cell (RBC) distribution width (RDW) were determined in all the subjects at baseline and at the end of the study. Results Serum vitamin D significantly increased from 6.4 (4.2–9.6) ng/mL to 35.6 (25.8–47.5) ng/mL (p < 0.001) following the intervention. Furthermore, serum anti-Hsp27 titers were significantly lower after the 9-week vitamin D administration period (0.22 [0.12–0.33] optical density [OD] vs. 0.19 [0.11–0.31] OD; p = 0.002). A significant correlation was found between serum anti-Hsp27 and RDW (r = 0.13, p = 0.037). The reduction in RDW values after intervention was particularly evident in subjects with the greatest increase in serum vitamin D levels. Conclusions High-dose vitamin D supplementation was found to reduce antibody titers to Hsp27. Further randomized placebo-controlled trials are warranted to determine the long-term effect of vitamin D administration on the inflammatory process especially that associated with chronic disease." @default.
- W3005397796 created "2020-02-14" @default.
- W3005397796 creator A5004654354 @default.
- W3005397796 creator A5005361897 @default.
- W3005397796 creator A5006098830 @default.
- W3005397796 creator A5006198982 @default.
- W3005397796 creator A5012019120 @default.
- W3005397796 creator A5020968716 @default.
- W3005397796 creator A5028096132 @default.
- W3005397796 creator A5038854437 @default.
- W3005397796 date "2020-05-26" @default.
- W3005397796 modified "2023-10-18" @default.
- W3005397796 title "Effect of high-dose vitamin D supplementation on antibody titers to heat shock protein 27 in adolescent girls" @default.
- W3005397796 cites W1512936145 @default.
- W3005397796 cites W1555261042 @default.
- W3005397796 cites W1970178265 @default.
- W3005397796 cites W1970670165 @default.
- W3005397796 cites W1974483694 @default.
- W3005397796 cites W1977699070 @default.
- W3005397796 cites W1979693059 @default.
- W3005397796 cites W1996807630 @default.
- W3005397796 cites W1997344803 @default.
- W3005397796 cites W2006083207 @default.
- W3005397796 cites W2012699214 @default.
- W3005397796 cites W2014835001 @default.
- W3005397796 cites W2015706524 @default.
- W3005397796 cites W2022809525 @default.
- W3005397796 cites W2024877435 @default.
- W3005397796 cites W2027578103 @default.
- W3005397796 cites W2027727459 @default.
- W3005397796 cites W2028764252 @default.
- W3005397796 cites W2031084334 @default.
- W3005397796 cites W2037099609 @default.
- W3005397796 cites W2042948859 @default.
- W3005397796 cites W2053459026 @default.
- W3005397796 cites W2057828982 @default.
- W3005397796 cites W2065600132 @default.
- W3005397796 cites W2070609609 @default.
- W3005397796 cites W2074332495 @default.
- W3005397796 cites W2078706933 @default.
- W3005397796 cites W2083373216 @default.
- W3005397796 cites W2083809911 @default.
- W3005397796 cites W2087717115 @default.
- W3005397796 cites W2094354621 @default.
- W3005397796 cites W2095483193 @default.
- W3005397796 cites W2097784085 @default.
- W3005397796 cites W2101364296 @default.
- W3005397796 cites W2101756176 @default.
- W3005397796 cites W2111188705 @default.
- W3005397796 cites W2118188310 @default.
- W3005397796 cites W2123346488 @default.
- W3005397796 cites W2124821571 @default.
- W3005397796 cites W2125581987 @default.
- W3005397796 cites W2126574528 @default.
- W3005397796 cites W2137528384 @default.
- W3005397796 cites W2140095253 @default.
- W3005397796 cites W2153059487 @default.
- W3005397796 cites W2153100720 @default.
- W3005397796 cites W2164413420 @default.
- W3005397796 cites W2166658877 @default.
- W3005397796 cites W2169563954 @default.
- W3005397796 cites W2171479615 @default.
- W3005397796 cites W2409728396 @default.
- W3005397796 cites W2531702030 @default.
- W3005397796 cites W2605984608 @default.
- W3005397796 cites W2644577814 @default.
- W3005397796 cites W2762916207 @default.
- W3005397796 cites W2791407225 @default.
- W3005397796 cites W2805941025 @default.
- W3005397796 cites W2912401318 @default.
- W3005397796 cites W334106317 @default.
- W3005397796 cites W786963854 @default.
- W3005397796 cites W955752055 @default.
- W3005397796 doi "https://doi.org/10.1515/jpem-2019-0288" @default.
- W3005397796 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32352398" @default.
- W3005397796 hasPublicationYear "2020" @default.
- W3005397796 type Work @default.
- W3005397796 sameAs 3005397796 @default.
- W3005397796 citedByCount "3" @default.
- W3005397796 countsByYear W30053977962022 @default.
- W3005397796 countsByYear W30053977962023 @default.
- W3005397796 crossrefType "journal-article" @default.
- W3005397796 hasAuthorship W3005397796A5004654354 @default.
- W3005397796 hasAuthorship W3005397796A5005361897 @default.
- W3005397796 hasAuthorship W3005397796A5006098830 @default.
- W3005397796 hasAuthorship W3005397796A5006198982 @default.
- W3005397796 hasAuthorship W3005397796A5012019120 @default.
- W3005397796 hasAuthorship W3005397796A5020968716 @default.
- W3005397796 hasAuthorship W3005397796A5028096132 @default.
- W3005397796 hasAuthorship W3005397796A5038854437 @default.
- W3005397796 hasBestOaLocation W30053977962 @default.
- W3005397796 hasConcept C124490489 @default.
- W3005397796 hasConcept C126322002 @default.
- W3005397796 hasConcept C134018914 @default.
- W3005397796 hasConcept C142724271 @default.
- W3005397796 hasConcept C159654299 @default.
- W3005397796 hasConcept C203014093 @default.
- W3005397796 hasConcept C204787440 @default.