Matches in SemOpenAlex for { <https://semopenalex.org/work/W3005425809> ?p ?o ?g. }
- W3005425809 abstract "Stem cell therapy, which promotes stem cells differentiation towards specialized cell types, increases the resident population and production of extracellular matrix, and can be used to achieve intervertebral disc (IVD) repair, has drawn great attention for the development of IVD-regenerating materials. Many materials that have been reported in IVD repair have the ability to promote stem cells differentiation. However, due to the limitations of mechanical properties, immunogenicity and uncontrollable deviations in the induction of stem cells differentiation, there are few materials that can currently be translated into clinical applications. In addition to the favourable mechanical properties and biocompatibility of IVD materials, maintaining stem cells activity in the local niche and increasing the ability of stem cells to differentiate into nucleus pulposus (NP) and annulus fibrosus (AF) cells are the basis for promoting the application of IVD-regenerating materials in clinical practice. The purpose of this review is to summarize IVD-regenerating materials that focus on stem cells strategies, analyse the properties of these materials that affect the differentiation of stem cells into IVD-like cells, and then present the limitations of currently used disc materials in the field of stem cell therapy and future research perspectives." @default.
- W3005425809 created "2020-02-14" @default.
- W3005425809 creator A5022913770 @default.
- W3005425809 creator A5033409588 @default.
- W3005425809 creator A5075695445 @default.
- W3005425809 creator A5079578957 @default.
- W3005425809 creator A5080234213 @default.
- W3005425809 creator A5086823444 @default.
- W3005425809 date "2020-02-07" @default.
- W3005425809 modified "2023-10-02" @default.
- W3005425809 title "Biomaterials-Induced Stem Cells Specific Differentiation Into Intervertebral Disc Lineage Cells" @default.
- W3005425809 cites W1181717787 @default.
- W3005425809 cites W141721208 @default.
- W3005425809 cites W1520612770 @default.
- W3005425809 cites W1548830906 @default.
- W3005425809 cites W1573325432 @default.
- W3005425809 cites W1631840151 @default.
- W3005425809 cites W1828234663 @default.
- W3005425809 cites W1895071558 @default.
- W3005425809 cites W1966132868 @default.
- W3005425809 cites W1968859445 @default.
- W3005425809 cites W1973572775 @default.
- W3005425809 cites W1973996314 @default.
- W3005425809 cites W1981083884 @default.
- W3005425809 cites W1983636283 @default.
- W3005425809 cites W1990069138 @default.
- W3005425809 cites W1993680967 @default.
- W3005425809 cites W1994322581 @default.
- W3005425809 cites W1994436843 @default.
- W3005425809 cites W1997458448 @default.
- W3005425809 cites W2003312252 @default.
- W3005425809 cites W2003352875 @default.
- W3005425809 cites W2007013103 @default.
- W3005425809 cites W2007505738 @default.
- W3005425809 cites W2010080836 @default.
- W3005425809 cites W2018835937 @default.
- W3005425809 cites W2023969602 @default.
- W3005425809 cites W2028772826 @default.
- W3005425809 cites W2031446720 @default.
- W3005425809 cites W2038874386 @default.
- W3005425809 cites W2044978087 @default.
- W3005425809 cites W2050252270 @default.
- W3005425809 cites W2050475565 @default.
- W3005425809 cites W2058911609 @default.
- W3005425809 cites W2062217024 @default.
- W3005425809 cites W2062976745 @default.
- W3005425809 cites W2064091315 @default.
- W3005425809 cites W2064262977 @default.
- W3005425809 cites W2076667099 @default.
- W3005425809 cites W2077473779 @default.
- W3005425809 cites W2080763470 @default.
- W3005425809 cites W2085648623 @default.
- W3005425809 cites W2086211715 @default.
- W3005425809 cites W2088187155 @default.
- W3005425809 cites W2091372495 @default.
- W3005425809 cites W2092634358 @default.
- W3005425809 cites W2095157875 @default.
- W3005425809 cites W2106459436 @default.
- W3005425809 cites W2110986748 @default.
- W3005425809 cites W2111456102 @default.
- W3005425809 cites W2121924587 @default.
- W3005425809 cites W2135419008 @default.
- W3005425809 cites W2138199688 @default.
- W3005425809 cites W2138727973 @default.
- W3005425809 cites W2140617608 @default.
- W3005425809 cites W2142477000 @default.
- W3005425809 cites W2161860593 @default.
- W3005425809 cites W2163998809 @default.
- W3005425809 cites W2190515950 @default.
- W3005425809 cites W2190807767 @default.
- W3005425809 cites W2191225761 @default.
- W3005425809 cites W2233420651 @default.
- W3005425809 cites W2275798200 @default.
- W3005425809 cites W2278931003 @default.
- W3005425809 cites W2281730706 @default.
- W3005425809 cites W2290208967 @default.
- W3005425809 cites W2299397886 @default.
- W3005425809 cites W2301313079 @default.
- W3005425809 cites W2303065439 @default.
- W3005425809 cites W2326254565 @default.
- W3005425809 cites W2326761949 @default.
- W3005425809 cites W2345287433 @default.
- W3005425809 cites W2346620911 @default.
- W3005425809 cites W2390186479 @default.
- W3005425809 cites W2396904210 @default.
- W3005425809 cites W2399193895 @default.
- W3005425809 cites W2407366228 @default.
- W3005425809 cites W2412295127 @default.
- W3005425809 cites W2418084594 @default.
- W3005425809 cites W2429024809 @default.
- W3005425809 cites W2431250996 @default.
- W3005425809 cites W2464854598 @default.
- W3005425809 cites W2475478456 @default.
- W3005425809 cites W2514898346 @default.
- W3005425809 cites W2515556435 @default.
- W3005425809 cites W2521591018 @default.
- W3005425809 cites W2524571899 @default.
- W3005425809 cites W2549864445 @default.
- W3005425809 cites W2557975987 @default.
- W3005425809 cites W2562917375 @default.