Matches in SemOpenAlex for { <https://semopenalex.org/work/W3005472012> ?p ?o ?g. }
- W3005472012 endingPage "1659.e4" @default.
- W3005472012 startingPage "1644" @default.
- W3005472012 abstract "To study the development of the human retina, we use single-cell RNA sequencing (RNA-seq) at key fetal stages and follow the development of the major cell types as well as populations of transitional cells. We also analyze stem cell (hPSC)-derived retinal organoids; although organoids have a very similar cellular composition at equivalent ages as the fetal retina, there are some differences in gene expression of particular cell types. Moreover, the inner retinal lamination is disrupted at more advanced stages of organoids compared with fetal retina. To determine whether the disorganization in the inner retina is due to the culture conditions, we analyze retinal development in fetal retina maintained under similar conditions. These retinospheres develop for at least 6 months, displaying better inner retinal lamination than retinal organoids. Our single-cell RNA sequencing (scRNA-seq) comparisons of fetal retina, retinal organoids, and retinospheres provide a resource for developing better in vitro models for retinal disease." @default.
- W3005472012 created "2020-02-14" @default.
- W3005472012 creator A5001520984 @default.
- W3005472012 creator A5003360721 @default.
- W3005472012 creator A5010851453 @default.
- W3005472012 creator A5014099245 @default.
- W3005472012 creator A5016854384 @default.
- W3005472012 creator A5027767510 @default.
- W3005472012 creator A5057552749 @default.
- W3005472012 creator A5059609093 @default.
- W3005472012 creator A5063469751 @default.
- W3005472012 creator A5066634071 @default.
- W3005472012 creator A5067733367 @default.
- W3005472012 creator A5078845326 @default.
- W3005472012 date "2020-02-01" @default.
- W3005472012 modified "2023-10-10" @default.
- W3005472012 title "Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures" @default.
- W3005472012 cites W1518338854 @default.
- W3005472012 cites W1544267685 @default.
- W3005472012 cites W1820330395 @default.
- W3005472012 cites W1843828601 @default.
- W3005472012 cites W1895998181 @default.
- W3005472012 cites W1964163541 @default.
- W3005472012 cites W1971636570 @default.
- W3005472012 cites W1980980049 @default.
- W3005472012 cites W1982436843 @default.
- W3005472012 cites W1984883254 @default.
- W3005472012 cites W1988623932 @default.
- W3005472012 cites W1994009311 @default.
- W3005472012 cites W1994750743 @default.
- W3005472012 cites W1996609490 @default.
- W3005472012 cites W1997987643 @default.
- W3005472012 cites W2010837054 @default.
- W3005472012 cites W2013617404 @default.
- W3005472012 cites W2025555096 @default.
- W3005472012 cites W2025979279 @default.
- W3005472012 cites W2026135963 @default.
- W3005472012 cites W2027555661 @default.
- W3005472012 cites W2032155043 @default.
- W3005472012 cites W2036505824 @default.
- W3005472012 cites W2041598409 @default.
- W3005472012 cites W2055819347 @default.
- W3005472012 cites W2057550273 @default.
- W3005472012 cites W2073947789 @default.
- W3005472012 cites W2076780019 @default.
- W3005472012 cites W2080923518 @default.
- W3005472012 cites W2084196112 @default.
- W3005472012 cites W2098702533 @default.
- W3005472012 cites W2110263868 @default.
- W3005472012 cites W2118444666 @default.
- W3005472012 cites W2124008148 @default.
- W3005472012 cites W2130411917 @default.
- W3005472012 cites W2132408316 @default.
- W3005472012 cites W2153478200 @default.
- W3005472012 cites W2154710417 @default.
- W3005472012 cites W22535547 @default.
- W3005472012 cites W2267772868 @default.
- W3005472012 cites W2319627288 @default.
- W3005472012 cites W2338378167 @default.
- W3005472012 cites W2465295277 @default.
- W3005472012 cites W2589611970 @default.
- W3005472012 cites W2595472395 @default.
- W3005472012 cites W2596752718 @default.
- W3005472012 cites W2604275021 @default.
- W3005472012 cites W2745315781 @default.
- W3005472012 cites W2761739377 @default.
- W3005472012 cites W2768530411 @default.
- W3005472012 cites W2774151205 @default.
- W3005472012 cites W2775484513 @default.
- W3005472012 cites W2789621577 @default.
- W3005472012 cites W2791277809 @default.
- W3005472012 cites W2794480084 @default.
- W3005472012 cites W2794521141 @default.
- W3005472012 cites W2803616467 @default.
- W3005472012 cites W2806766888 @default.
- W3005472012 cites W2883266723 @default.
- W3005472012 cites W2893194701 @default.
- W3005472012 cites W2893675751 @default.
- W3005472012 cites W2896680207 @default.
- W3005472012 cites W2902652978 @default.
- W3005472012 cites W2903837331 @default.
- W3005472012 cites W2904334833 @default.
- W3005472012 cites W2912953959 @default.
- W3005472012 cites W2916020270 @default.
- W3005472012 cites W2919418800 @default.
- W3005472012 cites W2934006135 @default.
- W3005472012 cites W2944529335 @default.
- W3005472012 cites W2944813712 @default.
- W3005472012 cites W2946389085 @default.
- W3005472012 cites W2949177718 @default.
- W3005472012 cites W2951799803 @default.
- W3005472012 cites W2955320019 @default.
- W3005472012 doi "https://doi.org/10.1016/j.celrep.2020.01.007" @default.
- W3005472012 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7901645" @default.
- W3005472012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32023475" @default.
- W3005472012 hasPublicationYear "2020" @default.
- W3005472012 type Work @default.
- W3005472012 sameAs 3005472012 @default.