FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3005654808> ?p ?o ?g. }

• W3005654808 endingPage "355" @default.
• W3005654808 startingPage "348" @default.
• W3005654808 abstract "Digitaria ciliaris is widely reported to be a problematic weed in agricultural areas and is mainly used as an indicator plant for the development of herbicides. However, its bioactivities on skin regeneration and wound healing have not been investigated. In the present study, we investigated the effects of D. ciliaris flower absolute on skin wound healing and skin regeneration-related events, that is, proliferation, migration, and collagen biosynthesis, in human fibroblasts and keratinocytes. For this study, we extracted absolute from the D. ciliaris flower by solvent extraction and identified the composition of D. ciliaris flower absolute using GC/MS analysis. We also tested the effect of D. ciliaris flower absolute in CCD986sk fibroblasts and/or HaCaT keratinocytes using the WST assay and 5-bromo-2'-deoxyuridine incorporation assay, Boyden chamber assay, ELISA, sprouting assay, and immunoblotting. GC/MS analysis of D. ciliaris flower absolute revealed that it contained 15 compounds. The absolute increased the proliferations of keratinocytes and fibroblasts and the migration of fibroblasts but did not affect cell viabilities. In addition, it enhanced the syntheses of type I and IV collagen in fibroblasts, but not in keratinocytes. The sprouting assay showed increased sprout outgrowth of fibroblasts. In addition, D. ciliaris flower absolute induced the phosphorylation of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in fibroblasts. These results indicate that D. ciliaris flower absolute may promote skin wound healing/regeneration by inducing the proliferation, migration, and collagen synthesis of fibroblasts, as well as the proliferation of keratinocytes. Therefore, D. ciliaris flower absolute may be a potential natural source for cosmetic or pharmaceutical agents that promote skin wound healing/regeneration." @default.
• W3005654808 created "2020-02-24" @default.
• W3005654808 creator A5001672173 @default.
• W3005654808 creator A5017461555 @default.
• W3005654808 creator A5018324791 @default.
• W3005654808 creator A5023266017 @default.
• W3005654808 creator A5033535838 @default.
• W3005654808 creator A5041084728 @default.
• W3005654808 creator A5044300535 @default.
• W3005654808 date "2020-02-11" @default.
• W3005654808 modified "2023-10-16" @default.
• W3005654808 title "Potential Beneficial Effects of Digitaria ciliaris Flower Absolute on the Wound Healing-Linked Activities of Fibroblasts and Keratinocytes" @default.
• W3005654808 cites W1481511602 @default.
• W3005654808 cites W1583064681 @default.
• W3005654808 cites W1655029534 @default.
• W3005654808 cites W1931315964 @default.
• W3005654808 cites W1949832432 @default.
• W3005654808 cites W1965475066 @default.
• W3005654808 cites W1969482526 @default.
• W3005654808 cites W1972341000 @default.
• W3005654808 cites W1986353310 @default.
• W3005654808 cites W1987815584 @default.
• W3005654808 cites W2009166805 @default.
• W3005654808 cites W2021408555 @default.
• W3005654808 cites W2026620093 @default.
• W3005654808 cites W2030281917 @default.
• W3005654808 cites W2045232408 @default.
• W3005654808 cites W2063373395 @default.
• W3005654808 cites W2070995184 @default.
• W3005654808 cites W2075138251 @default.
• W3005654808 cites W2085987441 @default.
• W3005654808 cites W2091775384 @default.
• W3005654808 cites W2099588269 @default.
• W3005654808 cites W2107952710 @default.
• W3005654808 cites W2110206108 @default.
• W3005654808 cites W2119907368 @default.
• W3005654808 cites W2139283410 @default.
• W3005654808 cites W2143581668 @default.
• W3005654808 cites W2149614382 @default.
• W3005654808 cites W2154084053 @default.
• W3005654808 cites W2155230904 @default.
• W3005654808 cites W2156085609 @default.
• W3005654808 cites W2161727113 @default.
• W3005654808 cites W2167603487 @default.
• W3005654808 cites W2188921905 @default.
• W3005654808 cites W2281810024 @default.
• W3005654808 cites W2581701212 @default.
• W3005654808 cites W2594039483 @default.
• W3005654808 cites W2784063844 @default.
• W3005654808 cites W2804138314 @default.
• W3005654808 cites W2913089764 @default.
• W3005654808 cites W2940293610 @default.
• W3005654808 cites W2948082436 @default.
• W3005654808 cites W2954999525 @default.
• W3005654808 cites W3217001605 @default.
• W3005654808 cites W44581492 @default.
• W3005654808 doi "https://doi.org/10.1055/a-1101-9326" @default.
• W3005654808 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32045946" @default.
• W3005654808 hasPublicationYear "2020" @default.
• W3005654808 type Work @default.
• W3005654808 sameAs 3005654808 @default.
• W3005654808 citedByCount "5" @default.
• W3005654808 countsByYear W30056548082020 @default.
• W3005654808 countsByYear W30056548082021 @default.
• W3005654808 countsByYear W30056548082022 @default.
• W3005654808 crossrefType "journal-article" @default.
• W3005654808 hasAuthorship W3005654808A5001672173 @default.
• W3005654808 hasAuthorship W3005654808A5017461555 @default.
• W3005654808 hasAuthorship W3005654808A5018324791 @default.
• W3005654808 hasAuthorship W3005654808A5023266017 @default.
• W3005654808 hasAuthorship W3005654808A5033535838 @default.
• W3005654808 hasAuthorship W3005654808A5041084728 @default.
• W3005654808 hasAuthorship W3005654808A5044300535 @default.
• W3005654808 hasConcept C118995209 @default.
• W3005654808 hasConcept C153911025 @default.
• W3005654808 hasConcept C171056886 @default.
• W3005654808 hasConcept C185592680 @default.
• W3005654808 hasConcept C189165786 @default.
• W3005654808 hasConcept C202751555 @default.
• W3005654808 hasConcept C203014093 @default.
• W3005654808 hasConcept C2777074287 @default.
• W3005654808 hasConcept C2780269544 @default.
• W3005654808 hasConcept C2780381497 @default.
• W3005654808 hasConcept C55493867 @default.
• W3005654808 hasConcept C86803240 @default.
• W3005654808 hasConcept C95444343 @default.
• W3005654808 hasConceptScore W3005654808C118995209 @default.
• W3005654808 hasConceptScore W3005654808C153911025 @default.
• W3005654808 hasConceptScore W3005654808C171056886 @default.
• W3005654808 hasConceptScore W3005654808C185592680 @default.
• W3005654808 hasConceptScore W3005654808C189165786 @default.
• W3005654808 hasConceptScore W3005654808C202751555 @default.
• W3005654808 hasConceptScore W3005654808C203014093 @default.
• W3005654808 hasConceptScore W3005654808C2777074287 @default.
• W3005654808 hasConceptScore W3005654808C2780269544 @default.
• W3005654808 hasConceptScore W3005654808C2780381497 @default.
• W3005654808 hasConceptScore W3005654808C55493867 @default.
• W3005654808 hasConceptScore W3005654808C86803240 @default.

• next