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- W3005660007 abstract "Objectives: To explore structural variations of the circle of Willis using three-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA), and to compare this modality with digital subtraction angiography (DSA). Methods: A total of 819 consecutive patients suspected of having cerebral vascular diseases underwent 3D-TOF-MRA, followed by DSA within two weeks. We report accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 3D-TOF-MRA compared with DSA. Results: The sensitivity and specificity of combined analyses were 90-100% and 98 -100%, respectively. The sensitivity and NPV of 3D-TOF-MRA images for A-, C-, D- and H-types of circle of Willis anomalies were 100%. The specificity, accuracy and sensitivity were all 100% for detecting absence of the anterior communicating artery (ACOA). Sensitivity, specificity, PPV, and NPV were all 100% for detecting F-type. The sensitivity and PPV of volume rendered (VR) images for the B-, E-, and G-types were relatively low (85.0%, 86.2%, and 73.8% respectively). Maximum intensity projection (MIP) was somewhat better (88.3%, 89.2%, and 81.8% respectively). Combined analyses were better still (95.8%, 96.1%, and 99.0% respectively). Specificity and NPVs were high (99.3¬-100%). Conclusions: 3D-TOF-MRA compares well to DSA for evaluation of the structure of the circle of Willis. As 3D-TOF-MRA is a noninvasive modality, it may be preferred as a means to evaluate structural variations of the circle of Willis." @default.
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- W3005660007 date "2020-02-11" @default.
- W3005660007 modified "2023-10-16" @default.
- W3005660007 title "Examination of Structural Variations of the Circle of Willis by 3D Time-of-Flight Magnetic Resonance Angiography" @default.
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- W3005660007 doi "https://doi.org/10.3389/fnins.2020.00071" @default.
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