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- W3005718174 abstract "Throughout the last decades, dendritic cell (DC)-based anti-tumor vaccines have proven to be a safe therapeutic approach, although with inconsistent clinical results. The functional limitations of ex vivo monocyte-derived dendritic cells (MoDCs) commonly used in these therapies are one of the pointed explanations for their lack of robustness. Therefore, a great effort has been made to identify DC subsets with superior features for the establishment of effective anti-tumor responses and to apply them in therapeutic approaches. Among characterized human DC subpopulations, conventional type 1 DCs (cDC1) have emerged as a highly desirable tool for empowering anti-tumor immunity. This DC subset excels in its capacity to prime antigen-specific cytotoxic T cells and to activate natural killer (NK) and natural killer T (NKT) cells, which are critical factors for an effective anti-tumor immune response. Here, we sought to revise the immunobiology of cDC1 from their ontogeny to their development, regulation and heterogeneity. We also address the role of this functionally thrilling DC subset in anti-tumor immune responses and the most recent efforts to apply it in cancer immunotherapy." @default.
- W3005718174 created "2020-02-24" @default.
- W3005718174 creator A5004563369 @default.
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- W3005718174 creator A5074656365 @default.
- W3005718174 date "2020-02-15" @default.
- W3005718174 modified "2023-10-16" @default.
- W3005718174 title "Dendritic Cell Vaccines for Cancer Immunotherapy: The Role of Human Conventional Type 1 Dendritic Cells" @default.
- W3005718174 cites W1019458012 @default.
- W3005718174 cites W1468841000 @default.
- W3005718174 cites W1498931318 @default.
- W3005718174 cites W1533531903 @default.
- W3005718174 cites W1541265927 @default.
- W3005718174 cites W1541821188 @default.
- W3005718174 cites W1549882456 @default.
- W3005718174 cites W1587414944 @default.
- W3005718174 cites W1599718730 @default.
- W3005718174 cites W1862018296 @default.
- W3005718174 cites W1926326783 @default.
- W3005718174 cites W1964493928 @default.
- W3005718174 cites W1967660147 @default.
- W3005718174 cites W1968292598 @default.
- W3005718174 cites W1970839329 @default.
- W3005718174 cites W1976199086 @default.
- W3005718174 cites W1978494950 @default.
- W3005718174 cites W1978586979 @default.
- W3005718174 cites W1985444402 @default.
- W3005718174 cites W1987477455 @default.
- W3005718174 cites W2007026865 @default.
- W3005718174 cites W2019530616 @default.
- W3005718174 cites W2030710574 @default.
- W3005718174 cites W2031579865 @default.
- W3005718174 cites W2033899158 @default.
- W3005718174 cites W2033937518 @default.
- W3005718174 cites W2046505430 @default.
- W3005718174 cites W2049429882 @default.
- W3005718174 cites W2049751829 @default.
- W3005718174 cites W2056628849 @default.
- W3005718174 cites W2062254683 @default.
- W3005718174 cites W2064194595 @default.
- W3005718174 cites W2065593489 @default.
- W3005718174 cites W2068046103 @default.
- W3005718174 cites W2072691337 @default.
- W3005718174 cites W2072733008 @default.
- W3005718174 cites W2076534074 @default.
- W3005718174 cites W2082962820 @default.
- W3005718174 cites W2087979291 @default.
- W3005718174 cites W2089187782 @default.
- W3005718174 cites W2089477918 @default.
- W3005718174 cites W2090483939 @default.
- W3005718174 cites W2091019029 @default.
- W3005718174 cites W2095921413 @default.
- W3005718174 cites W2098873148 @default.
- W3005718174 cites W2103959341 @default.
- W3005718174 cites W2106137449 @default.
- W3005718174 cites W2106511557 @default.
- W3005718174 cites W2110974754 @default.
- W3005718174 cites W2111975769 @default.
- W3005718174 cites W2113896298 @default.
- W3005718174 cites W2115453935 @default.
- W3005718174 cites W2117129729 @default.
- W3005718174 cites W2120315525 @default.
- W3005718174 cites W2126705611 @default.
- W3005718174 cites W2127144270 @default.
- W3005718174 cites W2130621814 @default.
- W3005718174 cites W2133019048 @default.
- W3005718174 cites W2136883776 @default.
- W3005718174 cites W2142357559 @default.
- W3005718174 cites W2142530756 @default.
- W3005718174 cites W2143669011 @default.
- W3005718174 cites W2143772132 @default.
- W3005718174 cites W2148461908 @default.
- W3005718174 cites W2148510816 @default.
- W3005718174 cites W2149134183 @default.
- W3005718174 cites W2153135025 @default.
- W3005718174 cites W2153503451 @default.
- W3005718174 cites W2155400409 @default.
- W3005718174 cites W2156244509 @default.
- W3005718174 cites W2164462649 @default.
- W3005718174 cites W2166285267 @default.
- W3005718174 cites W2168028214 @default.
- W3005718174 cites W2168401979 @default.
- W3005718174 cites W2169324807 @default.
- W3005718174 cites W2177971463 @default.
- W3005718174 cites W2180091996 @default.
- W3005718174 cites W2196638295 @default.
- W3005718174 cites W2201541946 @default.
- W3005718174 cites W2332062962 @default.
- W3005718174 cites W2338985623 @default.
- W3005718174 cites W2341604280 @default.
- W3005718174 cites W2345568581 @default.
- W3005718174 cites W2397459368 @default.
- W3005718174 cites W2404096427 @default.