Matches in SemOpenAlex for { <https://semopenalex.org/work/W3005762667> ?p ?o ?g. }
- W3005762667 abstract "Recent advances in technology over the last decades have strived to elucidate the diverse and abundant ecosystem of the human microbiome. The intestinal microbiota represents a densely inhabited environment that offers a plethora of beneficial effects to the host's wellbeing. On the other hand, it can serve as a potential reservoir of Multi-Drug Resistant (MDR) bacteria and their antibiotic-resistant genes (ARgenes), which comprise the gut resistome. ARgenes, like antibiotics, have been omnipresent in the environment for billions of years. In the context of the gut microbiome, these genes may conflate into exogenous MDR or emerge in commensals due to mutations or gene transfers. It is currently generally accepted that Antimicrobial Resistance (AMR) poses a serious threat to public health worldwide. It is of paramount importance that researchers focus on, amongst other parameters, elaborating strategies to manage the gut resistome, particularly focusing on the diminution of AMR. Potential interventions in the gut microbiome field by Fecal Microbiota Transplant (FMT) or functional foods are newly emerged candidates for the uprooting of MDR strains and restoring dysbiosis and resilience. Probiotic nutrition is thought to diminish gut colonization from pathobionts. Yet only a few studies have explored the effects of antibiotics use on the reservoir of AR genes and the demanding time for return to normal by gut microbiota-targeted strategies. Regular administration of probiotic bacteria has recently been linked to restoration of the gut ecosystem and decrease of the gut resistome and AR genes carriers. This review summarizes the latest information about the intestinal resistome and the intriguing methods of fighting against AMR through probiotic-based methods and gut microbial shifts that have been proposed. This study contains some key messages: (1) AMR currently poses a lethal threat to global health, and it is pivotal for the scientific community to do its utmost in fighting against it; (2) human gut microbiome research, within the last decade especially, seems to be preoccupied with the interface of numerous diseases and identifying a potential target for a variety of interventions; (3) the gut resistome, comprised of AR genesis, presents very early on in life and is prone to shifts due to the use of antibiotics or dietary supplements; and (4) future strategies involving functional foods seem promising for the battle against AMR through intestinal resistome diminution." @default.
- W3005762667 created "2020-02-24" @default.
- W3005762667 creator A5035050571 @default.
- W3005762667 creator A5047281963 @default.
- W3005762667 creator A5071387705 @default.
- W3005762667 creator A5075094506 @default.
- W3005762667 creator A5088438373 @default.
- W3005762667 date "2020-02-11" @default.
- W3005762667 modified "2023-10-17" @default.
- W3005762667 title "Potential Elimination of Human Gut Resistome by Exploiting the Benefits of Functional Foods" @default.
- W3005762667 cites W1509413299 @default.
- W3005762667 cites W1803443273 @default.
- W3005762667 cites W1893993890 @default.
- W3005762667 cites W1932345506 @default.
- W3005762667 cites W2005377507 @default.
- W3005762667 cites W2007110604 @default.
- W3005762667 cites W2016375372 @default.
- W3005762667 cites W2023630186 @default.
- W3005762667 cites W2027831845 @default.
- W3005762667 cites W2027951608 @default.
- W3005762667 cites W2032230795 @default.
- W3005762667 cites W2041543427 @default.
- W3005762667 cites W2046501778 @default.
- W3005762667 cites W2058415702 @default.
- W3005762667 cites W2065088137 @default.
- W3005762667 cites W2074390927 @default.
- W3005762667 cites W2081028022 @default.
- W3005762667 cites W2084057318 @default.
- W3005762667 cites W2084646638 @default.
- W3005762667 cites W2089797945 @default.
- W3005762667 cites W2091588484 @default.
- W3005762667 cites W2116846792 @default.
- W3005762667 cites W2118629634 @default.
- W3005762667 cites W2124253153 @default.
- W3005762667 cites W2128956666 @default.
- W3005762667 cites W2129690444 @default.
- W3005762667 cites W2131186249 @default.
- W3005762667 cites W2131919079 @default.
- W3005762667 cites W2133167298 @default.
- W3005762667 cites W2133218356 @default.
- W3005762667 cites W2143196592 @default.
- W3005762667 cites W2144852012 @default.
- W3005762667 cites W2151450070 @default.
- W3005762667 cites W2151814510 @default.
- W3005762667 cites W2154179335 @default.
- W3005762667 cites W2160268203 @default.
- W3005762667 cites W2165003751 @default.
- W3005762667 cites W2166801599 @default.
- W3005762667 cites W2170196186 @default.
- W3005762667 cites W2194744065 @default.
- W3005762667 cites W2197330023 @default.
- W3005762667 cites W2242390630 @default.
- W3005762667 cites W2325656813 @default.
- W3005762667 cites W2331182329 @default.
- W3005762667 cites W2331300001 @default.
- W3005762667 cites W2342887013 @default.
- W3005762667 cites W2383908672 @default.
- W3005762667 cites W2408650239 @default.
- W3005762667 cites W2569903275 @default.
- W3005762667 cites W2610116465 @default.
- W3005762667 cites W2616825195 @default.
- W3005762667 cites W2620042743 @default.
- W3005762667 cites W2725570802 @default.
- W3005762667 cites W2746392566 @default.
- W3005762667 cites W2763934336 @default.
- W3005762667 cites W2767051074 @default.
- W3005762667 cites W2783843471 @default.
- W3005762667 cites W2788835903 @default.
- W3005762667 cites W2790152383 @default.
- W3005762667 cites W2792808282 @default.
- W3005762667 cites W2807266621 @default.
- W3005762667 cites W2808457437 @default.
- W3005762667 cites W2809017655 @default.
- W3005762667 cites W2811583889 @default.
- W3005762667 cites W2883937104 @default.
- W3005762667 cites W2884262556 @default.
- W3005762667 cites W2885836988 @default.
- W3005762667 cites W2889819256 @default.
- W3005762667 cites W2890924527 @default.
- W3005762667 cites W2900984733 @default.
- W3005762667 cites W2901088447 @default.
- W3005762667 cites W2905128082 @default.
- W3005762667 cites W2909668868 @default.
- W3005762667 cites W2912940347 @default.
- W3005762667 cites W2919346978 @default.
- W3005762667 cites W2952564192 @default.
- W3005762667 cites W2960310932 @default.
- W3005762667 cites W2966854986 @default.
- W3005762667 cites W2972082446 @default.
- W3005762667 cites W2990579599 @default.
- W3005762667 cites W4231110705 @default.
- W3005762667 doi "https://doi.org/10.3389/fmicb.2020.00050" @default.
- W3005762667 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7026006" @default.
- W3005762667 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32117102" @default.
- W3005762667 hasPublicationYear "2020" @default.
- W3005762667 type Work @default.
- W3005762667 sameAs 3005762667 @default.
- W3005762667 citedByCount "23" @default.
- W3005762667 countsByYear W30057626672020 @default.
- W3005762667 countsByYear W30057626672021 @default.