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- W3005805054 abstract "Background Measurement of reticulocyte hemoglobin equivalent (RET-He) is rapid, convenient, and cost-effective. Yet, researches on its performance in diagnosing iron deficiency with concurrent inflammation are limited. Hence, this study investigated RET-He value in various states, including inflammation, and evaluated its diagnostic performance in iron status assessment. Methods Retrospectively, 953 clinical data and laboratory results-complete blood count, reticulocyte count, RET-He, and serum ferritin-were reviewed. Patients on iron therapy were excluded. Iron status was defined by serum ferritin as the reference method. RET-He among populations was investigated. Its diagnostic performance and optimal cutoff were determined by ROC analysis. Results Three population groups were classified: healthy control, iron deficiency anemia (IDA), and non-ID anemia. Significantly, RET-He value in IDA was lower than that of healthy control, anemia of inflammation, and chronic kidney disease (P 30 pg signifies a non-IDA state. Conclusion In addition to convenience and cost-effectiveness, RET-He cutoff >30 pg can be potentially used to exclude IDA due to its excellent diagnostic sensitivity and specificity." @default.
- W3005805054 created "2020-02-24" @default.
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- W3005805054 date "2020-02-11" @default.
- W3005805054 modified "2023-10-13" @default.
- W3005805054 title "Diagnostic performance of reticulocyte hemoglobin equivalent in assessing the iron status" @default.
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- W3005805054 doi "https://doi.org/10.1002/jcla.23225" @default.
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