FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3005996363> ?p ?o ?g. }

• W3005996363 endingPage "e0229111" @default.
• W3005996363 startingPage "e0229111" @default.
• W3005996363 abstract "Despite the success of prevention of mother to child transmission (PMTCT) program in South Africa, the 30% HIV prevalence among women of childbearing age requires the PMTCT program to be maximally efficient to sustain gains in the prevention of vertical HIV transmission. We aimed to determine the immunologic and virologic status at entry into antenatal care (ANC) and at childbirth among HIV positive women who conceived under the CD4<500 cells/μl antiretroviral therapy (ART) eligibility threshold and universal test and treat (UTT) policies in the Gauteng province of South Africa.We conducted a retrospective cohort study of 692 HIV positive adult (>18 years) postpartum women who gave birth between September 2016 and December 2017. Demographic, viral load (VL) and CD4 data at ANC start (3-9 months before delivery) and delivery (3 months before/after) were obtained from medical records of consenting women. We compared CD4≥500 cell/μl and viral load (VL) suppression (<400 copes/ml) rates at ANC start and delivery among women with a pre-pregnancy ART, women known HIV positive but with in-pregnancy ART and newly diagnosed women with in-pregnancy ART. Predictors of having a high CD4 and suppressed VL were assessed by log-binomial regression.Of the 692 participants, 394 (57.0%) had CD4 data and 326 (47.1%) had VL data. Overall women with a pre-pregnancy ART were more likely to start ANC with CD4 count≥500 cell/μl (46.3% vs 24.8%, adjusted risk ratio (aRR) = 1.9; 95% confidence interval (95% CI): 1.4-2.5), compared to newly diagnosed women. This difference was no longer apparent at the time of delivery (aRR 1.2 95% CI: 0.4-3.7). Similarly, viral suppression at delivery was higher among women with pre-pregnancy ART (87.2% vs 69.3%, aRR 1.3, 95% CI: 1.1-1.6) as compared to the newly diagnosed women. Viral suppression rate among newly diagnosed women increased substantially by the time of delivery from 43.5% to 69.3% (p = 0.001).These results show that pre-pregnancy ART improves immunologic and virologic control during pregnancy and call for renewed efforts in HIV testing, linkage to ART and viral monitoring." @default.
• W3005996363 created "2020-02-24" @default.
• W3005996363 creator A5010355168 @default.
• W3005996363 creator A5025948549 @default.
• W3005996363 creator A5036851385 @default.
• W3005996363 creator A5038337241 @default.
• W3005996363 creator A5078326361 @default.
• W3005996363 date "2020-02-13" @default.
• W3005996363 modified "2023-10-16" @default.
• W3005996363 title "Time of HIV diagnosis, CD4 count and viral load at antenatal care start and delivery in South Africa" @default.
• W3005996363 cites W1503928853 @default.
• W3005996363 cites W1866229248 @default.
• W3005996363 cites W1964867999 @default.
• W3005996363 cites W2031659816 @default.
• W3005996363 cites W2068171571 @default.
• W3005996363 cites W2075461127 @default.
• W3005996363 cites W2081545515 @default.
• W3005996363 cites W2082836772 @default.
• W3005996363 cites W2086127866 @default.
• W3005996363 cites W2087371207 @default.
• W3005996363 cites W2087696064 @default.
• W3005996363 cites W2107331394 @default.
• W3005996363 cites W2111910501 @default.
• W3005996363 cites W2116465729 @default.
• W3005996363 cites W2126184004 @default.
• W3005996363 cites W2363480212 @default.
• W3005996363 cites W2610581664 @default.
• W3005996363 cites W2766990575 @default.
• W3005996363 cites W2794608950 @default.
• W3005996363 cites W2795836598 @default.
• W3005996363 cites W2805590490 @default.
• W3005996363 cites W2809692725 @default.
• W3005996363 cites W2884073176 @default.
• W3005996363 cites W2913170605 @default.
• W3005996363 cites W2931681725 @default.
• W3005996363 cites W4235080258 @default.
• W3005996363 cites W4244058896 @default.
• W3005996363 cites W4293052483 @default.
• W3005996363 doi "https://doi.org/10.1371/journal.pone.0229111" @default.
• W3005996363 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7018033" @default.
• W3005996363 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32053679" @default.
• W3005996363 hasPublicationYear "2020" @default.
• W3005996363 type Work @default.
• W3005996363 sameAs 3005996363 @default.
• W3005996363 citedByCount "2" @default.
• W3005996363 countsByYear W30059963632022 @default.
• W3005996363 countsByYear W30059963632023 @default.
• W3005996363 crossrefType "journal-article" @default.
• W3005996363 hasAuthorship W3005996363A5010355168 @default.
• W3005996363 hasAuthorship W3005996363A5025948549 @default.
• W3005996363 hasAuthorship W3005996363A5036851385 @default.
• W3005996363 hasAuthorship W3005996363A5038337241 @default.
• W3005996363 hasAuthorship W3005996363A5078326361 @default.
• W3005996363 hasBestOaLocation W30059963631 @default.
• W3005996363 hasConcept C119599485 @default.
• W3005996363 hasConcept C126322002 @default.
• W3005996363 hasConcept C127413603 @default.
• W3005996363 hasConcept C131872663 @default.
• W3005996363 hasConcept C142462285 @default.
• W3005996363 hasConcept C167135981 @default.
• W3005996363 hasConcept C187212893 @default.
• W3005996363 hasConcept C203014093 @default.
• W3005996363 hasConcept C2779234561 @default.
• W3005996363 hasConcept C2779703513 @default.
• W3005996363 hasConcept C3013748606 @default.
• W3005996363 hasConcept C44249647 @default.
• W3005996363 hasConcept C54355233 @default.
• W3005996363 hasConcept C71924100 @default.
• W3005996363 hasConcept C761482 @default.
• W3005996363 hasConcept C86803240 @default.
• W3005996363 hasConceptScore W3005996363C119599485 @default.
• W3005996363 hasConceptScore W3005996363C126322002 @default.
• W3005996363 hasConceptScore W3005996363C127413603 @default.
• W3005996363 hasConceptScore W3005996363C131872663 @default.
• W3005996363 hasConceptScore W3005996363C142462285 @default.
• W3005996363 hasConceptScore W3005996363C167135981 @default.
• W3005996363 hasConceptScore W3005996363C187212893 @default.
• W3005996363 hasConceptScore W3005996363C203014093 @default.
• W3005996363 hasConceptScore W3005996363C2779234561 @default.
• W3005996363 hasConceptScore W3005996363C2779703513 @default.
• W3005996363 hasConceptScore W3005996363C3013748606 @default.
• W3005996363 hasConceptScore W3005996363C44249647 @default.
• W3005996363 hasConceptScore W3005996363C54355233 @default.
• W3005996363 hasConceptScore W3005996363C71924100 @default.
• W3005996363 hasConceptScore W3005996363C761482 @default.
• W3005996363 hasConceptScore W3005996363C86803240 @default.
• W3005996363 hasFunder F4320310979 @default.
• W3005996363 hasIssue "2" @default.
• W3005996363 hasLocation W30059963631 @default.
• W3005996363 hasLocation W30059963632 @default.
• W3005996363 hasLocation W30059963633 @default.
• W3005996363 hasLocation W30059963634 @default.
• W3005996363 hasLocation W30059963635 @default.
• W3005996363 hasOpenAccess W3005996363 @default.
• W3005996363 hasPrimaryLocation W30059963631 @default.
• W3005996363 hasRelatedWork W2418172017 @default.
• W3005996363 hasRelatedWork W2470633880 @default.
• W3005996363 hasRelatedWork W2502930894 @default.

• next