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• W3006450388 startingPage "1018" @default.
• W3006450388 abstract "DELLA proteins are repressors of the gibberellin (GA) hormone signaling pathway that act mainly by regulating transcription factor activities in plants. GAs induce DELLA repressor protein degradation and thereby control a number of critical developmental processes as well as responses to stresses such as cold. The strong effect of cold temperatures on many physiological processes has rendered it difficult to assess, based on phenotypic criteria, the role of GA and DELLAs in plant growth during cold stress. Here, we uncover substantial differences in the GA transcriptomes between plants grown at ambient temperature (21°C) and plants exposed to cold stress (4°C) in Arabidopsis (Arabidopsis thaliana). We further identify over 250, to the largest extent previously unknown, DELLA-transcription factor interactions using the yeast two-hybrid system. By integrating both data sets, we reveal that most members of the nine-member GRF (GROWTH REGULATORY FACTOR) transcription factor family are DELLA interactors and, at the same time, that several GRF genes are targets of DELLA-modulated transcription after exposure to cold stress. We find that plants with altered GRF dosage are differentially sensitive to the manipulation of GA and hence DELLA levels, also after cold stress, and identify a subset of cold stress-responsive genes that qualify as targets of this DELLA-GRF regulatory module." @default.
• W3006450388 created "2020-02-24" @default.
• W3006450388 creator A5055776595 @default.
• W3006450388 creator A5057590954 @default.
• W3006450388 creator A5081793291 @default.
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• W3006450388 date "2020-02-14" @default.
• W3006450388 modified "2023-10-18" @default.
• W3006450388 title "GROWTH-REGULATING FACTORS Interact with DELLAs and Regulate Growth in Cold Stress" @default.
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• W3006450388 doi "https://doi.org/10.1105/tpc.19.00784" @default.
• W3006450388 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7145461" @default.
• W3006450388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32060178" @default.
• W3006450388 hasPublicationYear "2020" @default.
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