Matches in SemOpenAlex for { <https://semopenalex.org/work/W3006606082> ?p ?o ?g. }
- W3006606082 endingPage "97" @default.
- W3006606082 startingPage "97" @default.
- W3006606082 abstract "Increasing evidence indicates a relationship between cannabis use and psychosis risk. Specific factors, such as determinants of cannabis use or the genetic profile of cannabis users, appear to moderate this association. The present systematic review presents a detailed and up-to-date literature overview on factors that influence the relationship between cannabis use and psychosis risk. A systematic search was performed according to the PRISMA guidelines in MEDLINE and Embase, and 56 studies were included. The results show that, in particular, frequent cannabis use, especially daily use, and the consumption of high-potency cannabis are associated with a higher risk of developing psychosis. Moreover, several genotypes moderate the impact of cannabis use on psychosis risk, particularly those involved in the dopamine function, such as AKT1. Finally, cannabis use is associated with an earlier psychosis onset and increased risk of transition in individuals at a clinical high risk of psychosis. These findings indicate that changing cannabis use behavior could be a harm reduction strategy employed to lower the risk of developing psychosis. Future research should aim to further develop specific biomarkers and genetic profiles for psychosis, thereby contributing to the identification of individuals at the highest risk of developing a psychotic disorder." @default.
- W3006606082 created "2020-02-24" @default.
- W3006606082 creator A5016165999 @default.
- W3006606082 creator A5030548033 @default.
- W3006606082 creator A5052910579 @default.
- W3006606082 date "2020-02-12" @default.
- W3006606082 modified "2023-10-11" @default.
- W3006606082 title "Factors Moderating the Association between Cannabis Use and Psychosis Risk: A Systematic Review" @default.
- W3006606082 cites W1532526167 @default.
- W3006606082 cites W1750202769 @default.
- W3006606082 cites W1923030578 @default.
- W3006606082 cites W1965585096 @default.
- W3006606082 cites W1968429271 @default.
- W3006606082 cites W1973952134 @default.
- W3006606082 cites W1982903278 @default.
- W3006606082 cites W1986059489 @default.
- W3006606082 cites W1990719986 @default.
- W3006606082 cites W1994139936 @default.
- W3006606082 cites W1996171185 @default.
- W3006606082 cites W1996278273 @default.
- W3006606082 cites W1999561105 @default.
- W3006606082 cites W2007118330 @default.
- W3006606082 cites W2007497521 @default.
- W3006606082 cites W2008842720 @default.
- W3006606082 cites W2016013658 @default.
- W3006606082 cites W2016169730 @default.
- W3006606082 cites W2016732910 @default.
- W3006606082 cites W2017730736 @default.
- W3006606082 cites W2019502220 @default.
- W3006606082 cites W2021859916 @default.
- W3006606082 cites W2022847865 @default.
- W3006606082 cites W2023923490 @default.
- W3006606082 cites W2029388920 @default.
- W3006606082 cites W2034089230 @default.
- W3006606082 cites W2040333240 @default.
- W3006606082 cites W2049453530 @default.
- W3006606082 cites W2052554576 @default.
- W3006606082 cites W2052712301 @default.
- W3006606082 cites W2052794650 @default.
- W3006606082 cites W2054856852 @default.
- W3006606082 cites W2061139636 @default.
- W3006606082 cites W2061510253 @default.
- W3006606082 cites W2067571259 @default.
- W3006606082 cites W2071528273 @default.
- W3006606082 cites W2079284092 @default.
- W3006606082 cites W2084804423 @default.
- W3006606082 cites W2096003899 @default.
- W3006606082 cites W2098392054 @default.
- W3006606082 cites W2099241624 @default.
- W3006606082 cites W2101357408 @default.
- W3006606082 cites W2102581653 @default.
- W3006606082 cites W2102856705 @default.
- W3006606082 cites W2103177499 @default.
- W3006606082 cites W2103756711 @default.
- W3006606082 cites W2104532446 @default.
- W3006606082 cites W2105124760 @default.
- W3006606082 cites W2105527159 @default.
- W3006606082 cites W2110339257 @default.
- W3006606082 cites W2113426703 @default.
- W3006606082 cites W2118656309 @default.
- W3006606082 cites W2118829128 @default.
- W3006606082 cites W2119780182 @default.
- W3006606082 cites W2122251240 @default.
- W3006606082 cites W2126551481 @default.
- W3006606082 cites W2129378060 @default.
- W3006606082 cites W2131485275 @default.
- W3006606082 cites W2132971116 @default.
- W3006606082 cites W2134882014 @default.
- W3006606082 cites W2135363891 @default.
- W3006606082 cites W2135461650 @default.
- W3006606082 cites W2137495999 @default.
- W3006606082 cites W2138566108 @default.
- W3006606082 cites W2139701553 @default.
- W3006606082 cites W2141798721 @default.
- W3006606082 cites W2143899242 @default.
- W3006606082 cites W2144625250 @default.
- W3006606082 cites W2146519036 @default.
- W3006606082 cites W2146561516 @default.
- W3006606082 cites W2149290648 @default.
- W3006606082 cites W2153320925 @default.
- W3006606082 cites W2153372311 @default.
- W3006606082 cites W2156098321 @default.
- W3006606082 cites W2156291077 @default.
- W3006606082 cites W2158274508 @default.
- W3006606082 cites W2161346464 @default.
- W3006606082 cites W2161411148 @default.
- W3006606082 cites W2166288728 @default.
- W3006606082 cites W2169269177 @default.
- W3006606082 cites W2169551361 @default.
- W3006606082 cites W2171396692 @default.
- W3006606082 cites W2194134502 @default.
- W3006606082 cites W2269558388 @default.
- W3006606082 cites W2272477495 @default.
- W3006606082 cites W2274449219 @default.
- W3006606082 cites W2286619620 @default.
- W3006606082 cites W2325308941 @default.
- W3006606082 cites W2408738151 @default.
- W3006606082 cites W246286872 @default.