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- W3006656199 abstract "Whether burning-out of the gland, i.e. progressive parenchymal destruction, leads to pain decrease has been repeatedly debated. 8,9 The group of Ammann has claimed that pain decreases with increasing duration of the disease.3,lo,1l In one long-term study, 85% of 145 patients with chronic pancreatitis felt no more pain after 4.5 years (median) duration of the disease.3 The reports from Zurich are at variance with the studies from Japan and Germany. Miyake et al. 6 found that only 48.2% of the patients with chronic pancre atitis became free of pain within 5 years, and 66-73% after more than 5 years. That meant that every third or fourth patient still suffered from relapsing pain attacks even after a longer observation time. Our group7 reported that the incidence of relapsing pain attacks decreased during the observation period, but more than half of the patients (53%) still suffered from relapsing pain attacks even after more than 10 years of observation (Table 15.1).7 At present, the course of pain in alcoholic and idiopathic chronic pancreatitis remains unclarified. Layer et al. l2 investigated a group of patients with idio pathic chronic pancreatitis who had never consumed alcoholic beverages during their life time. They found that patients with early-onset pancreatitis (onset at 35 years) have a mild and often painless course. Both forms differ from alcoholic pancreatitis in the equal gender distribution and a much slower rate of calcification. In contrast, our group13 found that the course of pain is the same in alcohol- and" @default.
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- W3006656199 date "2004-01-01" @default.
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- W3006656199 title "15 Natural Course of Chronic Pancreatitis" @default.
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