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- W3006806992 abstract "A tumor-targeting drug delivery system consists of a tumor recognition moiety and a directly linked cytotoxic agent or an agent attached to a water-soluble synthetic polymer carrier through a suitable linker. Conjugation of a drug with a polymer carrier can change its solubility, toxicity, biodistribution, blood clearance and therapeutic specificity. Increased therapeutic specificity of a polymer drug can be achieved by the attachment of a targeting moiety (e.g. a lectin, protein, antibody, or peptide) that specifically interacts with receptors on the target cells. A large number of tumor-specific peptides were described in recent years. After a short introduction, some important examples of peptide-targeted conjugates will be described and discussed." @default.
- W3006806992 created "2020-03-06" @default.
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- W3006806992 date "2016-09-17" @default.
- W3006806992 modified "2023-09-26" @default.
- W3006806992 title "Peptide-Targeted Polymer Cancerostatics" @default.
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- W3006806992 doi "https://doi.org/10.33549/physiolres.933418" @default.
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