Matches in SemOpenAlex for { <https://semopenalex.org/work/W3006836706> ?p ?o ?g. }
- W3006836706 endingPage "735163" @default.
- W3006836706 startingPage "735163" @default.
- W3006836706 abstract "The blunt snout bream (Megalobrama amblycephala, BSB) is important economic fish, but it is sensitive to hypoxia. To overcome this shortcoming, we previously obtained gynogenetic blunt snout bream (GBSB) with the enhanced ability to resist hypoxia. To explore the molecular mechanisms underlying the enhanced hypoxia tolerance of GBSB as a result of gynogenesis, in the present study, we conducted the comparative analyses of the liver transcriptomes of GBSB and BSB under normoxic conditions and identified differentially expressed genes (DEGs). Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis showed that many DEGs were enriched in the NF-kappa B signaling pathway (flip, nfkb2, cxcl8, il1b, tnfaip3, nfkbia, cox2, pias4, ube2i, malt1), hypoxia-inducible factor-1 (HIF-1) signaling pathway (hif-1α, vegfa, pfkfb2, glut1, hk), FOXO signaling pathway (pi3k, sgk1, foxo1, prmt1, pcka), and glycolysis/gluconeogenesis pathway (pgm, hk, aldo, pcka, gapa, acs). In addition, the average concentration of hemoglobin, which might be related to the NF-kappa B and HIF-1 signaling pathways, was higher in GBSB than in BSB (p < 0.05). This study provided important information regarding the potential molecular mechanisms underlying hypoxia tolerance in the GBSB, presenting further evidence for the enhanced ability to resist hypoxia in GBSB, which is significant for fish genetic breeding." @default.
- W3006836706 created "2020-03-06" @default.
- W3006836706 creator A5008231346 @default.
- W3006836706 creator A5008551422 @default.
- W3006836706 creator A5019935534 @default.
- W3006836706 creator A5025369532 @default.
- W3006836706 creator A5029850708 @default.
- W3006836706 creator A5057121941 @default.
- W3006836706 creator A5058026071 @default.
- W3006836706 creator A5059736823 @default.
- W3006836706 creator A5063315923 @default.
- W3006836706 creator A5071871752 @default.
- W3006836706 creator A5077934134 @default.
- W3006836706 creator A5086038672 @default.
- W3006836706 creator A5087653918 @default.
- W3006836706 creator A5090134632 @default.
- W3006836706 date "2020-06-01" @default.
- W3006836706 modified "2023-10-14" @default.
- W3006836706 title "Comparative analysis of liver transcriptomes associated with hypoxia tolerance in the gynogenetic blunt snout bream" @default.
- W3006836706 cites W1495010802 @default.
- W3006836706 cites W1529455781 @default.
- W3006836706 cites W1543587531 @default.
- W3006836706 cites W1966105954 @default.
- W3006836706 cites W1976408225 @default.
- W3006836706 cites W1979254457 @default.
- W3006836706 cites W1984789650 @default.
- W3006836706 cites W1992942194 @default.
- W3006836706 cites W1993078436 @default.
- W3006836706 cites W1997971145 @default.
- W3006836706 cites W1999892865 @default.
- W3006836706 cites W2003780050 @default.
- W3006836706 cites W2008308093 @default.
- W3006836706 cites W2008946188 @default.
- W3006836706 cites W2014562678 @default.
- W3006836706 cites W2014766558 @default.
- W3006836706 cites W2022259919 @default.
- W3006836706 cites W2022451432 @default.
- W3006836706 cites W2022478798 @default.
- W3006836706 cites W2026963192 @default.
- W3006836706 cites W2030410762 @default.
- W3006836706 cites W2057427519 @default.
- W3006836706 cites W2057652942 @default.
- W3006836706 cites W2059269274 @default.
- W3006836706 cites W2065664211 @default.
- W3006836706 cites W2087040133 @default.
- W3006836706 cites W2093500588 @default.
- W3006836706 cites W2095262349 @default.
- W3006836706 cites W2095793094 @default.
- W3006836706 cites W2102311561 @default.
- W3006836706 cites W2102860523 @default.
- W3006836706 cites W2105867638 @default.
- W3006836706 cites W2120970586 @default.
- W3006836706 cites W2126419817 @default.
- W3006836706 cites W2136725286 @default.
- W3006836706 cites W2141458291 @default.
- W3006836706 cites W2151862116 @default.
- W3006836706 cites W2156054670 @default.
- W3006836706 cites W2159717790 @default.
- W3006836706 cites W2164494194 @default.
- W3006836706 cites W2165463056 @default.
- W3006836706 cites W2179438025 @default.
- W3006836706 cites W2343444766 @default.
- W3006836706 cites W2581160324 @default.
- W3006836706 cites W2592392936 @default.
- W3006836706 cites W2604528893 @default.
- W3006836706 cites W2607473021 @default.
- W3006836706 cites W2727819897 @default.
- W3006836706 cites W2800745126 @default.
- W3006836706 cites W2803922716 @default.
- W3006836706 cites W2886715262 @default.
- W3006836706 cites W2915084928 @default.
- W3006836706 cites W2953535587 @default.
- W3006836706 doi "https://doi.org/10.1016/j.aquaculture.2020.735163" @default.
- W3006836706 hasPublicationYear "2020" @default.
- W3006836706 type Work @default.
- W3006836706 sameAs 3006836706 @default.
- W3006836706 citedByCount "23" @default.
- W3006836706 countsByYear W30068367062021 @default.
- W3006836706 countsByYear W30068367062022 @default.
- W3006836706 countsByYear W30068367062023 @default.
- W3006836706 crossrefType "journal-article" @default.
- W3006836706 hasAuthorship W3006836706A5008231346 @default.
- W3006836706 hasAuthorship W3006836706A5008551422 @default.
- W3006836706 hasAuthorship W3006836706A5019935534 @default.
- W3006836706 hasAuthorship W3006836706A5025369532 @default.
- W3006836706 hasAuthorship W3006836706A5029850708 @default.
- W3006836706 hasAuthorship W3006836706A5057121941 @default.
- W3006836706 hasAuthorship W3006836706A5058026071 @default.
- W3006836706 hasAuthorship W3006836706A5059736823 @default.
- W3006836706 hasAuthorship W3006836706A5063315923 @default.
- W3006836706 hasAuthorship W3006836706A5071871752 @default.
- W3006836706 hasAuthorship W3006836706A5077934134 @default.
- W3006836706 hasAuthorship W3006836706A5086038672 @default.
- W3006836706 hasAuthorship W3006836706A5087653918 @default.
- W3006836706 hasAuthorship W3006836706A5090134632 @default.
- W3006836706 hasConcept C104317684 @default.
- W3006836706 hasConcept C150194340 @default.
- W3006836706 hasConcept C152724338 @default.