FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3006949515> ?p ?o ?g. }

• W3006949515 endingPage "230" @default.
• W3006949515 startingPage "223" @default.
• W3006949515 abstract "The primary objective of this study was to examine the relationship of longitudinal changes in autonomic symptom burden and longitudinal changes in activities of daily living (ADLs); a secondary analysis examined the impact of depressive symptoms in this relationship.Data were retrieved from the Parkinson's Progression Markers Initiative (PPMI), a dataset documenting the natural history of newly diagnosed Parkinson's disease (PD). The analysis focused on data from baseline, visit 6 (24 months after enrollment), and visit 12 (60 months after enrollment). The impact of longitudinal changes in autonomic symptom burden on longitudinal changes in ADLs function was examined. A secondary mediation analysis was performed to investigate whether longitudinal changes in depressive symptoms mediate the relationship between longitudinal changes in autonomic symptom burden and ADLs function.Changes in autonomic symptom burden, cognitive function, depressive symptoms, and motor function all correlated with ADLs. Only changes in ADLs and depression were found to be associated with changes in autonomic symptom burden. We found that longitudinal change in autonomic symptoms was a significant predictor of change in ADLs at 24 and 60 months after enrollment, with the cardiovascular subscore being a major driver of this association. Mediation analysis revealed that the association between autonomic symptoms and ADLs is partially mediated by depressive symptoms.Longitudinal changes in autonomic symptoms impact ADLs function in patients with early signs of PD, both directly and indirectly through their impact on depressive symptoms. Future investigation into the influence of treatment of these symptoms on outcomes in PD is warranted." @default.
• W3006949515 created "2020-03-06" @default.
• W3006949515 creator A5005610052 @default.
• W3006949515 creator A5023779111 @default.
• W3006949515 creator A5029606463 @default.
• W3006949515 creator A5035355821 @default.
• W3006949515 creator A5050948560 @default.
• W3006949515 creator A5084142815 @default.
• W3006949515 date "2020-02-20" @default.
• W3006949515 modified "2023-10-18" @default.
• W3006949515 title "Longitudinal change in autonomic symptoms predicts activities of daily living and depression in Parkinson’s disease" @default.
• W3006949515 cites W1978793359 @default.
• W3006949515 cites W1979217137 @default.
• W3006949515 cites W1980508260 @default.
• W3006949515 cites W1981491878 @default.
• W3006949515 cites W1983228216 @default.
• W3006949515 cites W1988494453 @default.
• W3006949515 cites W2001666803 @default.
• W3006949515 cites W2005532083 @default.
• W3006949515 cites W2009501816 @default.
• W3006949515 cites W2034688662 @default.
• W3006949515 cites W2037646312 @default.
• W3006949515 cites W2042158944 @default.
• W3006949515 cites W2044745807 @default.
• W3006949515 cites W2046355981 @default.
• W3006949515 cites W2069680394 @default.
• W3006949515 cites W2072509938 @default.
• W3006949515 cites W2112519660 @default.
• W3006949515 cites W2140978740 @default.
• W3006949515 cites W2145954079 @default.
• W3006949515 cites W2146210116 @default.
• W3006949515 cites W2146552439 @default.
• W3006949515 cites W2165758561 @default.
• W3006949515 cites W2168132298 @default.
• W3006949515 cites W2405540958 @default.
• W3006949515 cites W2518704184 @default.
• W3006949515 cites W2649593040 @default.
• W3006949515 cites W2778855371 @default.
• W3006949515 cites W2781039296 @default.
• W3006949515 cites W2802324252 @default.
• W3006949515 cites W2901762925 @default.
• W3006949515 cites W2947760688 @default.
• W3006949515 cites W2959802936 @default.
• W3006949515 doi "https://doi.org/10.1007/s10286-020-00672-7" @default.
• W3006949515 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32078091" @default.
• W3006949515 hasPublicationYear "2020" @default.
• W3006949515 type Work @default.
• W3006949515 sameAs 3006949515 @default.
• W3006949515 citedByCount "12" @default.
• W3006949515 countsByYear W30069495152020 @default.
• W3006949515 countsByYear W30069495152021 @default.
• W3006949515 countsByYear W30069495152022 @default.
• W3006949515 crossrefType "journal-article" @default.
• W3006949515 hasAuthorship W3006949515A5005610052 @default.
• W3006949515 hasAuthorship W3006949515A5023779111 @default.
• W3006949515 hasAuthorship W3006949515A5029606463 @default.
• W3006949515 hasAuthorship W3006949515A5035355821 @default.
• W3006949515 hasAuthorship W3006949515A5050948560 @default.
• W3006949515 hasAuthorship W3006949515A5084142815 @default.
• W3006949515 hasBestOaLocation W30069495152 @default.
• W3006949515 hasConcept C118552586 @default.
• W3006949515 hasConcept C126322002 @default.
• W3006949515 hasConcept C139719470 @default.
• W3006949515 hasConcept C142724271 @default.
• W3006949515 hasConcept C162324750 @default.
• W3006949515 hasConcept C169900460 @default.
• W3006949515 hasConcept C17744445 @default.
• W3006949515 hasConcept C179420905 @default.
• W3006949515 hasConcept C1862650 @default.
• W3006949515 hasConcept C199539241 @default.
• W3006949515 hasConcept C2776867660 @default.
• W3006949515 hasConcept C2777895361 @default.
• W3006949515 hasConcept C2779134260 @default.
• W3006949515 hasConcept C2779734285 @default.
• W3006949515 hasConcept C3019858935 @default.
• W3006949515 hasConcept C71924100 @default.
• W3006949515 hasConcept C79544238 @default.
• W3006949515 hasConcept C99508421 @default.
• W3006949515 hasConceptScore W3006949515C118552586 @default.
• W3006949515 hasConceptScore W3006949515C126322002 @default.
• W3006949515 hasConceptScore W3006949515C139719470 @default.
• W3006949515 hasConceptScore W3006949515C142724271 @default.
• W3006949515 hasConceptScore W3006949515C162324750 @default.
• W3006949515 hasConceptScore W3006949515C169900460 @default.
• W3006949515 hasConceptScore W3006949515C17744445 @default.
• W3006949515 hasConceptScore W3006949515C179420905 @default.
• W3006949515 hasConceptScore W3006949515C1862650 @default.
• W3006949515 hasConceptScore W3006949515C199539241 @default.
• W3006949515 hasConceptScore W3006949515C2776867660 @default.
• W3006949515 hasConceptScore W3006949515C2777895361 @default.
• W3006949515 hasConceptScore W3006949515C2779134260 @default.
• W3006949515 hasConceptScore W3006949515C2779734285 @default.
• W3006949515 hasConceptScore W3006949515C3019858935 @default.
• W3006949515 hasConceptScore W3006949515C71924100 @default.
• W3006949515 hasConceptScore W3006949515C79544238 @default.
• W3006949515 hasConceptScore W3006949515C99508421 @default.
• W3006949515 hasIssue "3" @default.
• W3006949515 hasLocation W30069495151 @default.

• next