FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3006953991> ?p ?o ?g. }

• W3006953991 endingPage "534" @default.
• W3006953991 startingPage "526" @default.
• W3006953991 abstract "Tributyltin chloride (TBT-Cl) residual in water body had become a noticeable ecological problem for aquatic ecosystems. Toll-like receptors (TLRs) are an ancient family of pattern recognition receptors that play key roles in detecting nonself antigens and immune system activation. In this study, we explored the effect of TBT-Cl exposure on four TLRs expression in river pufferfish, Takifugu obscurus. The four T. obscurus Toll-like receptors (To-TLRs) contained different types of domains such as leucine-rich repeats (LRRs), leucine-rich repeats, typical subfamily (LRR_TYP) and other special domains. The To-TLRs mRNA transcripts expressed in all tissues, also To-TLR2 was investigated with higher level in kidney, as well as To-TLR3 in kidney, while To-TLR18 in liver and To-TLR22 in intestine. After the acute and chronic exposure of TBT-Cl, To-TLR2 and To-TLR3 mRNA transcripts were significantly down-regulated in gill. However, To-TLR18 and To-TLR22 were significantly up-regulated in gill and liver. Moreover, the histology and immunohistochemistry (IHC) results showed the different injury degrees of TBT-Cl in liver and gill and implied the cytoplasm reorganization after TBT-Cl stress and the function of immunoregulation for To-TLRs to TBT-Cl exposure. All the results indicated that To-TLRs might involve in sensing and mediating innate immune responses caused by TBT-Cl for keeping detoxification homeostasis." @default.
• W3006953991 created "2020-03-06" @default.
• W3006953991 creator A5041053461 @default.
• W3006953991 creator A5043361671 @default.
• W3006953991 creator A5069133334 @default.
• W3006953991 date "2020-04-01" @default.
• W3006953991 modified "2023-09-26" @default.
• W3006953991 title "Toll-like receptors (TLRs) respond to tributyltin chloride (TBT-Cl) exposure in the river pufferfish (Takifugu obscurus): Evidences for its toxic injury function" @default.
• W3006953991 cites W1483386514 @default.
• W3006953991 cites W1534675570 @default.
• W3006953991 cites W1544251308 @default.
• W3006953991 cites W1592284289 @default.
• W3006953991 cites W1650179436 @default.
• W3006953991 cites W1733534154 @default.
• W3006953991 cites W1965788199 @default.
• W3006953991 cites W1967696649 @default.
• W3006953991 cites W1975146958 @default.
• W3006953991 cites W1979070912 @default.
• W3006953991 cites W1981400681 @default.
• W3006953991 cites W1982577466 @default.
• W3006953991 cites W1991592979 @default.
• W3006953991 cites W1993058098 @default.
• W3006953991 cites W1995573039 @default.
• W3006953991 cites W1999536433 @default.
• W3006953991 cites W2001873744 @default.
• W3006953991 cites W2002747155 @default.
• W3006953991 cites W2003815900 @default.
• W3006953991 cites W2007912393 @default.
• W3006953991 cites W2008889685 @default.
• W3006953991 cites W2013083146 @default.
• W3006953991 cites W2015237638 @default.
• W3006953991 cites W2015666913 @default.
• W3006953991 cites W2022221710 @default.
• W3006953991 cites W2035666822 @default.
• W3006953991 cites W2054538838 @default.
• W3006953991 cites W2059003362 @default.
• W3006953991 cites W2060124909 @default.
• W3006953991 cites W2069846072 @default.
• W3006953991 cites W2069884916 @default.
• W3006953991 cites W2070168643 @default.
• W3006953991 cites W2070841084 @default.
• W3006953991 cites W2071889908 @default.
• W3006953991 cites W2079605309 @default.
• W3006953991 cites W2082897117 @default.
• W3006953991 cites W2096368515 @default.
• W3006953991 cites W2100343814 @default.
• W3006953991 cites W2103148772 @default.
• W3006953991 cites W2112176050 @default.
• W3006953991 cites W2112855364 @default.
• W3006953991 cites W2114570899 @default.
• W3006953991 cites W2116766330 @default.
• W3006953991 cites W2122315165 @default.
• W3006953991 cites W2130421043 @default.
• W3006953991 cites W2141218739 @default.
• W3006953991 cites W2145321747 @default.
• W3006953991 cites W2170949754 @default.
• W3006953991 cites W2197188534 @default.
• W3006953991 cites W2313090104 @default.
• W3006953991 cites W2339075713 @default.
• W3006953991 cites W2363854365 @default.
• W3006953991 cites W2465188505 @default.
• W3006953991 cites W2580389666 @default.
• W3006953991 cites W2765907662 @default.
• W3006953991 cites W2889216363 @default.
• W3006953991 cites W2902685697 @default.
• W3006953991 cites W2904469027 @default.
• W3006953991 cites W2950432996 @default.
• W3006953991 cites W2963752638 @default.
• W3006953991 cites W2994826464 @default.
• W3006953991 cites W4249383371 @default.
• W3006953991 doi "https://doi.org/10.1016/j.fsi.2020.02.050" @default.
• W3006953991 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32097718" @default.
• W3006953991 hasPublicationYear "2020" @default.
• W3006953991 type Work @default.
• W3006953991 sameAs 3006953991 @default.
• W3006953991 citedByCount "11" @default.
• W3006953991 countsByYear W30069539912021 @default.
• W3006953991 countsByYear W30069539912022 @default.
• W3006953991 countsByYear W30069539912023 @default.
• W3006953991 crossrefType "journal-article" @default.
• W3006953991 hasAuthorship W3006953991A5041053461 @default.
• W3006953991 hasAuthorship W3006953991A5043361671 @default.
• W3006953991 hasAuthorship W3006953991A5069133334 @default.
• W3006953991 hasConcept C136449434 @default.
• W3006953991 hasConcept C170493617 @default.
• W3006953991 hasConcept C18903297 @default.
• W3006953991 hasConcept C203014093 @default.
• W3006953991 hasConcept C2776070231 @default.
• W3006953991 hasConcept C2776709828 @default.
• W3006953991 hasConcept C2779078112 @default.
• W3006953991 hasConcept C2781236682 @default.
• W3006953991 hasConcept C55493867 @default.
• W3006953991 hasConcept C86803240 @default.
• W3006953991 hasConcept C8891405 @default.
• W3006953991 hasConcept C95444343 @default.
• W3006953991 hasConceptScore W3006953991C136449434 @default.
• W3006953991 hasConceptScore W3006953991C170493617 @default.
• W3006953991 hasConceptScore W3006953991C18903297 @default.

• next