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- W3007164906 abstract "Abstract Current preclinical cognitive assessments are highly time intensive, with lengthy assessment procedures. In this regard, a single‐day assay that focuses just on assessing learning behavior in a time‐effective and relatable manner would be of value. This article describes the box maze as a short‐term behavioral procedure to measure learning in mice. The protocol consists of allowing mice to explore an enclosed space that has eight holes. One of these holes leads to a tunnel that connects to an escape cage, and the latency to enter this escape hole is recorded for each mouse. Mice are tested four times within a single day, and the decrease in escape latency over time is used as a measure of learning. Age is a factor that affects escape latency in the box maze. Hence, the box‐maze procedure is proposed as an efficient test to probe aging and aging intervention–related research questions. © 2020 by John Wiley & Sons, Inc." @default.
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- W3007164906 date "2020-02-25" @default.
- W3007164906 modified "2023-10-11" @default.
- W3007164906 title "A Novel One‐Day Learning Procedure for Mice" @default.
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- W3007164906 doi "https://doi.org/10.1002/cpmo.68" @default.
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