Matches in SemOpenAlex for { <https://semopenalex.org/work/W3007173654> ?p ?o ?g. }
- W3007173654 endingPage "941" @default.
- W3007173654 startingPage "931" @default.
- W3007173654 abstract "Age-related pathological alterations of the vasculature have a critical role in morbidity and mortality of older adults. In epidemiological studies, age is the single most important cardiovascular risk factor that dwarfs the impact of traditional risk factors. To develop novel therapeutic interventions for prevention of age-related vascular pathologies, it is crucial to understand the cellular and molecular mechanisms of vascular aging. In this review, shared molecular mechanisms of aging are considered in terms of their contribution to the pathogenesis of macrovascular and microvascular diseases associated with old age. The role of cellular senescence in development of vascular aging phenotypes is highlighted, and potential interventions to prevent senescence and to eliminate senescent cells for prevention of vascular pathologies are presented. The evidence supporting a role for interorgan communication and circulating progeronic and antigeronic factors in vascular aging is discussed." @default.
- W3007173654 created "2020-03-06" @default.
- W3007173654 creator A5020830848 @default.
- W3007173654 creator A5021282382 @default.
- W3007173654 creator A5026936534 @default.
- W3007173654 creator A5042577204 @default.
- W3007173654 creator A5086692319 @default.
- W3007173654 date "2020-03-01" @default.
- W3007173654 modified "2023-10-14" @default.
- W3007173654 title "Mechanisms of Vascular Aging, A Geroscience Perspective" @default.
- W3007173654 cites W1591200751 @default.
- W3007173654 cites W1965575508 @default.
- W3007173654 cites W1966300199 @default.
- W3007173654 cites W1988236300 @default.
- W3007173654 cites W1990682984 @default.
- W3007173654 cites W2034366812 @default.
- W3007173654 cites W2044175055 @default.
- W3007173654 cites W2047538260 @default.
- W3007173654 cites W2059278059 @default.
- W3007173654 cites W2067028731 @default.
- W3007173654 cites W2069357463 @default.
- W3007173654 cites W2069519394 @default.
- W3007173654 cites W2096706830 @default.
- W3007173654 cites W2101833366 @default.
- W3007173654 cites W2108887402 @default.
- W3007173654 cites W2113495231 @default.
- W3007173654 cites W2115224024 @default.
- W3007173654 cites W2118597422 @default.
- W3007173654 cites W2122073743 @default.
- W3007173654 cites W2126525177 @default.
- W3007173654 cites W2135804517 @default.
- W3007173654 cites W2146417688 @default.
- W3007173654 cites W2155937098 @default.
- W3007173654 cites W2167408001 @default.
- W3007173654 cites W2170389508 @default.
- W3007173654 cites W2170947936 @default.
- W3007173654 cites W2264758825 @default.
- W3007173654 cites W2266290735 @default.
- W3007173654 cites W2273856223 @default.
- W3007173654 cites W2328110145 @default.
- W3007173654 cites W2362472309 @default.
- W3007173654 cites W2412713463 @default.
- W3007173654 cites W2544670169 @default.
- W3007173654 cites W2550166770 @default.
- W3007173654 cites W2583867813 @default.
- W3007173654 cites W2756868862 @default.
- W3007173654 cites W2778009820 @default.
- W3007173654 cites W2789470723 @default.
- W3007173654 cites W2796629168 @default.
- W3007173654 cites W2803815839 @default.
- W3007173654 cites W2860743873 @default.
- W3007173654 cites W2891919070 @default.
- W3007173654 cites W2900575344 @default.
- W3007173654 cites W2916248238 @default.
- W3007173654 cites W2922173223 @default.
- W3007173654 cites W2938269442 @default.
- W3007173654 cites W3015544325 @default.
- W3007173654 doi "https://doi.org/10.1016/j.jacc.2019.11.061" @default.
- W3007173654 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8559983" @default.
- W3007173654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32130929" @default.
- W3007173654 hasPublicationYear "2020" @default.
- W3007173654 type Work @default.
- W3007173654 sameAs 3007173654 @default.
- W3007173654 citedByCount "106" @default.
- W3007173654 countsByYear W30071736542020 @default.
- W3007173654 countsByYear W30071736542021 @default.
- W3007173654 countsByYear W30071736542022 @default.
- W3007173654 countsByYear W30071736542023 @default.
- W3007173654 crossrefType "journal-article" @default.
- W3007173654 hasAuthorship W3007173654A5020830848 @default.
- W3007173654 hasAuthorship W3007173654A5021282382 @default.
- W3007173654 hasAuthorship W3007173654A5026936534 @default.
- W3007173654 hasAuthorship W3007173654A5042577204 @default.
- W3007173654 hasAuthorship W3007173654A5086692319 @default.
- W3007173654 hasBestOaLocation W30071736542 @default.
- W3007173654 hasConcept C104317684 @default.
- W3007173654 hasConcept C107130276 @default.
- W3007173654 hasConcept C111472728 @default.
- W3007173654 hasConcept C118552586 @default.
- W3007173654 hasConcept C126322002 @default.
- W3007173654 hasConcept C127716648 @default.
- W3007173654 hasConcept C138885662 @default.
- W3007173654 hasConcept C142724271 @default.
- W3007173654 hasConcept C177713679 @default.
- W3007173654 hasConcept C207886595 @default.
- W3007173654 hasConcept C27415008 @default.
- W3007173654 hasConcept C2779523775 @default.
- W3007173654 hasConcept C2780942790 @default.
- W3007173654 hasConcept C500499127 @default.
- W3007173654 hasConcept C50440223 @default.
- W3007173654 hasConcept C522857546 @default.
- W3007173654 hasConcept C54355233 @default.
- W3007173654 hasConcept C60644358 @default.
- W3007173654 hasConcept C71924100 @default.
- W3007173654 hasConcept C86803240 @default.
- W3007173654 hasConcept C89611455 @default.
- W3007173654 hasConceptScore W3007173654C104317684 @default.
- W3007173654 hasConceptScore W3007173654C107130276 @default.