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- W3007187171 abstract "Both targeting and penetrating ability are the key characteristics for tissue probing and precise delivery. To construct an efficient nano probing and delivery system toward human epidermal growth factor receptor 2 (HER2) positive cancer, we established a nano liposomal system functionalized with a newly screened HER2 targeting peptide (HP2, YDLKEPEH) and the cell-penetrating peptide TAT simultaneously. Compared with the monofunctionalized liposomal probes, the dual-functional ones demonstrated a synergetic effect in cell uptake, drug delivery, and in vivo imaging. The improved efficacy of the synergetic system provides a prospective strategy for cancer diagnosis and therapy." @default.
- W3007187171 created "2020-03-06" @default.
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- W3007187171 date "2020-02-28" @default.
- W3007187171 modified "2023-10-16" @default.
- W3007187171 title "Synergetic Tumor Probes for Facilitating Therapeutic Delivery by Combined-Functionalized Peptide Ligands" @default.
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- W3007187171 doi "https://doi.org/10.1021/acs.analchem.0c00440" @default.
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