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• W3007385612 abstract "Endothelial activation and microvascular dysfunction are key pathogenic processes in severe malaria. We evaluated the early role of these processes in experimentally induced Plasmodium falciparum and P. vivax infection. Participants were enrolled in induced blood-stage malaria clinical trials. Plasma osteoprotegerin, angiopoietin-2, and von Willebrand Factor (vWF) levels were measured as biomarkers of endothelial activation. Microvascular function was assessed using peripheral arterial tonometry and near-infrared spectroscopy, and the endothelial glycocalyx was assessed by sublingual videomicroscopy and measurement of biomarkers of degradation." @default.
• W3007385612 created "2020-03-06" @default.
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• W3007385612 date "2020-04-20" @default.
• W3007385612 modified "2023-10-13" @default.
• W3007385612 title "Early Endothelial Activation Precedes Glycocalyx Degradation and Microvascular Dysfunction in Experimentally Induced Plasmodium falciparum and Plasmodium vivax Infection" @default.
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• W3007385612 doi "https://doi.org/10.1128/iai.00895-19" @default.
• W3007385612 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7171246" @default.
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