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- W3007709993 abstract "Thirty-two diterpenoids were obtained from the root bark of Pinus massoniana, and, among them, five compounds (pinmassins A–E) were identified as undescribed analogues. Spectroscopic methods, X-ray single-crystal diffraction analysis, and ECD calculations were applied to establish the structure of the new isolates. Pinmassin D (4) and abieta-8,11,13,15-tetraen-18-oic acid (23) showed moderate phosphodiesterase type 4D (PDE4D) inhibitory effects with IC50 values of 2.8 ± 0.18 and 3.3 ± 0.50 μM, respectively, and their binding modes were investigated by a molecular docking study." @default.
- W3007709993 created "2020-03-06" @default.
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- W3007709993 date "2020-02-26" @default.
- W3007709993 modified "2023-10-14" @default.
- W3007709993 title "Diterpenoids from the Root Bark of <i>Pinus massoniana</i> and Evaluation of Their Phosphodiesterase Type 4D Inhibitory Activity" @default.
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- W3007709993 doi "https://doi.org/10.1021/acs.jnatprod.9b01269" @default.
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