FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3007714069> ?p ?o ?g. }

• W3007714069 endingPage "1349" @default.
• W3007714069 startingPage "1341" @default.
• W3007714069 abstract "Abstract This clinical trial evaluated the independent and combined effects of a tricyclic antidepressant (desipramine) and cognitive behavioral therapy (CBT) for chronic back pain relative to an active placebo treatment. Participants (n = 142) were patients experiencing daily chronic back pain at an intensity of ≥4/10 who were randomized to a single-center, double-blind, 12-week, 4-arm, parallel groups controlled clinical trial of (1) low concentration desipramine titrated to reach a serum concentration level of 15 to 65 ng/mL; (2) CBT and active placebo medication (benztropine mesylate, 0.125 mg); (3) low concentration desipramine and CBT; and (4) active benztropine placebo medication. Participants completed the Differential Description Scale and Roland Morris Disability Questionnaires before and after treatment as validated measures of outcomes in back pain intensity and disability, respectively. Participants within each condition showed significant reductions from pre-treatment to post-treatment in pain intensity (mean changes ranged from = −2.58 to 3.87, Cohen's d's = 0.46-0.84) and improvements in pain disability (mean changes = −3.04 to 4.29, Cohen's d's = 0.54-0.88). However, intent-to-treat analyses at post-treatment showed no significant differences between any condition, with small effect sizes ranging from 0.06 to 0.27. The results from this clinical trial did not support the hypothesis that desipramine, CBT, or their combination would be statistically superior to an active medicine placebo for reducing chronic back pain intensity or disability. Key limitations included recruiting 71% of the planned sample size and use of multiple inclusion/exclusion criteria that may limit generalizability to broader populations of patients with chronic back pain." @default.
• W3007714069 created "2020-03-06" @default.
• W3007714069 creator A5009913262 @default.
• W3007714069 creator A5019668483 @default.
• W3007714069 creator A5019800364 @default.
• W3007714069 creator A5023172576 @default.
• W3007714069 creator A5040076878 @default.
• W3007714069 creator A5041894528 @default.
• W3007714069 creator A5045020425 @default.
• W3007714069 creator A5045474808 @default.
• W3007714069 creator A5049167907 @default.
• W3007714069 creator A5049172641 @default.
• W3007714069 creator A5049701813 @default.
• W3007714069 creator A5058078222 @default.
• W3007714069 creator A5076924093 @default.
• W3007714069 date "2020-02-12" @default.
• W3007714069 modified "2023-10-14" @default.
• W3007714069 title "A randomized placebo-controlled trial of desipramine, cognitive behavioral therapy, and active placebo therapy for low back pain" @default.
• W3007714069 cites W1968243597 @default.
• W3007714069 cites W1977911389 @default.
• W3007714069 cites W1979285610 @default.
• W3007714069 cites W1994241243 @default.
• W3007714069 cites W1996361295 @default.
• W3007714069 cites W1997096794 @default.
• W3007714069 cites W2002142158 @default.
• W3007714069 cites W2014777834 @default.
• W3007714069 cites W2015986868 @default.
• W3007714069 cites W2024451565 @default.
• W3007714069 cites W2035540128 @default.
• W3007714069 cites W2036884154 @default.
• W3007714069 cites W2046868700 @default.
• W3007714069 cites W2066348531 @default.
• W3007714069 cites W2068848266 @default.
• W3007714069 cites W2084250453 @default.
• W3007714069 cites W2095995963 @default.
• W3007714069 cites W2107662809 @default.
• W3007714069 cites W2108344016 @default.
• W3007714069 cites W2110535424 @default.
• W3007714069 cites W2118516436 @default.
• W3007714069 cites W2325063727 @default.
• W3007714069 cites W2515214979 @default.
• W3007714069 cites W2561831579 @default.
• W3007714069 cites W26265652 @default.
• W3007714069 cites W2743046890 @default.
• W3007714069 cites W2803665004 @default.
• W3007714069 cites W3194956376 @default.
• W3007714069 cites W4248297355 @default.
• W3007714069 doi "https://doi.org/10.1097/j.pain.0000000000001834" @default.
• W3007714069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32068667" @default.
• W3007714069 hasPublicationYear "2020" @default.
• W3007714069 type Work @default.
• W3007714069 sameAs 3007714069 @default.
• W3007714069 citedByCount "11" @default.
• W3007714069 countsByYear W30077140692020 @default.
• W3007714069 countsByYear W30077140692021 @default.
• W3007714069 countsByYear W30077140692022 @default.
• W3007714069 countsByYear W30077140692023 @default.
• W3007714069 crossrefType "journal-article" @default.
• W3007714069 hasAuthorship W3007714069A5009913262 @default.
• W3007714069 hasAuthorship W3007714069A5019668483 @default.
• W3007714069 hasAuthorship W3007714069A5019800364 @default.
• W3007714069 hasAuthorship W3007714069A5023172576 @default.
• W3007714069 hasAuthorship W3007714069A5040076878 @default.
• W3007714069 hasAuthorship W3007714069A5041894528 @default.
• W3007714069 hasAuthorship W3007714069A5045020425 @default.
• W3007714069 hasAuthorship W3007714069A5045474808 @default.
• W3007714069 hasAuthorship W3007714069A5049167907 @default.
• W3007714069 hasAuthorship W3007714069A5049172641 @default.
• W3007714069 hasAuthorship W3007714069A5049701813 @default.
• W3007714069 hasAuthorship W3007714069A5058078222 @default.
• W3007714069 hasAuthorship W3007714069A5076924093 @default.
• W3007714069 hasConcept C118552586 @default.
• W3007714069 hasConcept C126322002 @default.
• W3007714069 hasConcept C142724271 @default.
• W3007714069 hasConcept C15744967 @default.
• W3007714069 hasConcept C168563851 @default.
• W3007714069 hasConcept C1862650 @default.
• W3007714069 hasConcept C204787440 @default.
• W3007714069 hasConcept C27081682 @default.
• W3007714069 hasConcept C2779177272 @default.
• W3007714069 hasConcept C2780250439 @default.
• W3007714069 hasConcept C2781118164 @default.
• W3007714069 hasConcept C42219234 @default.
• W3007714069 hasConcept C558461103 @default.
• W3007714069 hasConcept C71924100 @default.
• W3007714069 hasConceptScore W3007714069C118552586 @default.
• W3007714069 hasConceptScore W3007714069C126322002 @default.
• W3007714069 hasConceptScore W3007714069C142724271 @default.
• W3007714069 hasConceptScore W3007714069C15744967 @default.
• W3007714069 hasConceptScore W3007714069C168563851 @default.
• W3007714069 hasConceptScore W3007714069C1862650 @default.
• W3007714069 hasConceptScore W3007714069C204787440 @default.
• W3007714069 hasConceptScore W3007714069C27081682 @default.
• W3007714069 hasConceptScore W3007714069C2779177272 @default.
• W3007714069 hasConceptScore W3007714069C2780250439 @default.
• W3007714069 hasConceptScore W3007714069C2781118164 @default.
• W3007714069 hasConceptScore W3007714069C42219234 @default.
• W3007714069 hasConceptScore W3007714069C558461103 @default.

• next