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• W3007751567 endingPage "126314" @default.
• W3007751567 startingPage "126314" @default.
• W3007751567 abstract "The dissolved oxygen concentration of the world's oceans has systematically declined by 2% over the past 50 years, and there has been a notable commensurate expansion of the global oxygen minimum zones (OMZs). Such wide-scale ocean deoxygenation affects the distribution of biological communities, impacts the physiology of organisms that may affect their capacity to absorb and process contaminants. Therefore, the bioaccumulation efficiencies of three contrasting radionuclides, 110mAg, 134Cs and 65Zn were investigated using controlled aquaria in the blue mussel Mytilus edulis under three contrasting dissolved oxygen regimes: normoxic; 7.14 mg L-1, reduced oxygen; 3.57 mg L-1 and hypoxic 1.78 mg L-1 conditions. Results indicated that hypoxic conditions diminished 110mAg uptake in the mussel, whereas depuration rates were not affected. Similarly, hypoxia appeared to cause a decrease in the 65Zn bioaccumulation rate, as evidenced by both weakened uptake and rapid elimination rates. Effects of hypoxia on the metabolome of mussels were also explored by untargeted Nuclear Magnetic Resonance (NMR) spectroscopic methods. The metabolic response was characterised by significantly greater abundance of several amino acids, amino sulfonic acids, dicarboxylic acids, carbohydrates and other metabolites in the lowest oxygen treatment, as compared to the higher oxygen treatments. Clearance rates significantly dropped in hypoxic conditions compared to normoxia. Results suggest that hypoxic conditions, and even partly moderate hypoxia, alter ventilation, an-aerobic, oxidative and osmoregulation metabolism of this mussel, which may further influence the trace element bioaccumulation capacity." @default.
• W3007751567 created "2020-03-06" @default.
• W3007751567 creator A5003004328 @default.
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• W3007751567 creator A5079133372 @default.
• W3007751567 date "2020-07-01" @default.
• W3007751567 modified "2023-09-24" @default.
• W3007751567 title "Effects of variable deoxygenation on trace element bioaccumulation and resulting metabolome profiles in the blue mussel (Mytilus edulis)" @default.
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• W3007751567 doi "https://doi.org/10.1016/j.chemosphere.2020.126314" @default.
• W3007751567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32234623" @default.
• W3007751567 hasPublicationYear "2020" @default.
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