Matches in SemOpenAlex for { <https://semopenalex.org/work/W3007761908> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W3007761908 abstract "The current pneumonia epidemic in China could evolve into a pandemic on a global scale if not effectively contained. The 2019-nCoV possesses a 61-amino acid open reading frame resembling SARS-CoV virulence factor - ORF6 peptide. The isoleucine content is 15.9% in ORF6 of SARS-CoV versus 16.4% of that in 2019-nCoV. Given the proton affinity in the carbonyl oxygen in isoleucine, augmented proton traffic can enhance proton-ion antiport and prompt cell swelling. As the content of essential amino acids in the open reading frame of 2019-nCoV reaches 57.4%, a starch/vitamin diet served for short period of time does not give rise to essential amino acids and halts virion production, which could be adopted as prophylactic approach of many viral infections. Plant-based diet or fasting/boiled rice water can also minimize the intake of essential amino acids or all amino acids respectively. Calorie restriction has been confirmed in animal studies to extend lifespan, and its underlying mechanism is not fully known. Furthermore, several proteins of 2019-nCoV possess high valine plus glycine content, which is implicated in heart disease." @default.
- W3007761908 created "2020-03-06" @default.
- W3007761908 creator A5006983054 @default.
- W3007761908 creator A5035221120 @default.
- W3007761908 creator A5042967060 @default.
- W3007761908 creator A5044041420 @default.
- W3007761908 creator A5048312229 @default.
- W3007761908 creator A5056904374 @default.
- W3007761908 creator A5064243515 @default.
- W3007761908 creator A5082658476 @default.
- W3007761908 creator A5085217990 @default.
- W3007761908 date "2020-02-20" @default.
- W3007761908 modified "2023-10-12" @default.
- W3007761908 title "The Wuhan Pneumonia Outbreak: High Isoleucine and High Valine Plus Glycine Contents Are Features of the Proteins of 2019-nCoV Virus" @default.
- W3007761908 cites W2075771884 @default.
- W3007761908 cites W2752808024 @default.
- W3007761908 cites W2901550516 @default.
- W3007761908 cites W2976093436 @default.
- W3007761908 cites W3001118548 @default.
- W3007761908 cites W3001465255 @default.
- W3007761908 doi "https://doi.org/10.20944/preprints202002.0289.v1" @default.
- W3007761908 hasPublicationYear "2020" @default.
- W3007761908 type Work @default.
- W3007761908 sameAs 3007761908 @default.
- W3007761908 citedByCount "0" @default.
- W3007761908 crossrefType "posted-content" @default.
- W3007761908 hasAuthorship W3007761908A5006983054 @default.
- W3007761908 hasAuthorship W3007761908A5035221120 @default.
- W3007761908 hasAuthorship W3007761908A5042967060 @default.
- W3007761908 hasAuthorship W3007761908A5044041420 @default.
- W3007761908 hasAuthorship W3007761908A5048312229 @default.
- W3007761908 hasAuthorship W3007761908A5056904374 @default.
- W3007761908 hasAuthorship W3007761908A5064243515 @default.
- W3007761908 hasAuthorship W3007761908A5082658476 @default.
- W3007761908 hasAuthorship W3007761908A5085217990 @default.
- W3007761908 hasBestOaLocation W30077619081 @default.
- W3007761908 hasConcept C104317684 @default.
- W3007761908 hasConcept C116675565 @default.
- W3007761908 hasConcept C159047783 @default.
- W3007761908 hasConcept C167625842 @default.
- W3007761908 hasConcept C185592680 @default.
- W3007761908 hasConcept C2776580952 @default.
- W3007761908 hasConcept C2777305461 @default.
- W3007761908 hasConcept C2777573094 @default.
- W3007761908 hasConcept C2777756961 @default.
- W3007761908 hasConcept C31903555 @default.
- W3007761908 hasConcept C47289529 @default.
- W3007761908 hasConcept C515207424 @default.
- W3007761908 hasConcept C55493867 @default.
- W3007761908 hasConcept C86803240 @default.
- W3007761908 hasConceptScore W3007761908C104317684 @default.
- W3007761908 hasConceptScore W3007761908C116675565 @default.
- W3007761908 hasConceptScore W3007761908C159047783 @default.
- W3007761908 hasConceptScore W3007761908C167625842 @default.
- W3007761908 hasConceptScore W3007761908C185592680 @default.
- W3007761908 hasConceptScore W3007761908C2776580952 @default.
- W3007761908 hasConceptScore W3007761908C2777305461 @default.
- W3007761908 hasConceptScore W3007761908C2777573094 @default.
- W3007761908 hasConceptScore W3007761908C2777756961 @default.
- W3007761908 hasConceptScore W3007761908C31903555 @default.
- W3007761908 hasConceptScore W3007761908C47289529 @default.
- W3007761908 hasConceptScore W3007761908C515207424 @default.
- W3007761908 hasConceptScore W3007761908C55493867 @default.
- W3007761908 hasConceptScore W3007761908C86803240 @default.
- W3007761908 hasLocation W30077619081 @default.
- W3007761908 hasOpenAccess W3007761908 @default.
- W3007761908 hasPrimaryLocation W30077619081 @default.
- W3007761908 hasRelatedWork W1943074550 @default.
- W3007761908 hasRelatedWork W1975808600 @default.
- W3007761908 hasRelatedWork W1989032592 @default.
- W3007761908 hasRelatedWork W2043394150 @default.
- W3007761908 hasRelatedWork W2188791186 @default.
- W3007761908 hasRelatedWork W2411850675 @default.
- W3007761908 hasRelatedWork W2473103804 @default.
- W3007761908 hasRelatedWork W4206076145 @default.
- W3007761908 hasRelatedWork W900855622 @default.
- W3007761908 hasRelatedWork W2421999865 @default.
- W3007761908 isParatext "false" @default.
- W3007761908 isRetracted "false" @default.
- W3007761908 magId "3007761908" @default.
- W3007761908 workType "article" @default.