FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3008049768> ?p ?o ?g. }

• W3008049768 endingPage "59" @default.
• W3008049768 startingPage "43" @default.
• W3008049768 abstract "Inflammation constitutes a concerted series of cellular and molecular responses that follow disturbance of systemic homeostasis, by either toxins or infectious organisms. Leukocytes modulate inflammation through production of secretory mediators, like cytokines and chemokines, which work in an autocrine and/or paracrine manner. These mediators can either promote or attenuate the inflammatory response and depending on differential temporal and spatial expression play a crucial role in the outcome of infection. Even though the objective is clearance of the pathogen with minimum damage to host, the pathogenesis of multiple human pathogenic viruses has been suggested to emanate from a dysregulation of the inflammatory response, sometimes with fatal consequences. This review discusses the nature and the outcome of inflammatory response, which is triggered in the human host subsequent to infection by single-sense plus-strand RNA viruses. In view of such harmful effects of a dysregulated inflammatory response, an exogenous regulation of these reactions by either interference or supplementation of critical regulators has been suggested. Currently multiple such factors are being tested for their beneficial and adverse effects. A successful use of such an approach in diseases of viral etiology can potentially protect the affected individual without directly affecting the virus life cycle. Further, such approaches whenever applicable would be useful in mitigating death and/or debility that is caused by the infection of those viruses which have proven particularly difficult to control by either prophylactic vaccines and/or therapeutic strategies using specific antiviral drugs." @default.
• W3008049768 created "2020-03-06" @default.
• W3008049768 creator A5075095640 @default.
• W3008049768 date "2020-01-01" @default.
• W3008049768 modified "2023-09-26" @default.
• W3008049768 title "Inflammation During Virus Infection: Swings and Roundabouts" @default.
• W3008049768 cites W1490536807 @default.
• W3008049768 cites W1494401243 @default.
• W3008049768 cites W1508832625 @default.
• W3008049768 cites W1509596990 @default.
• W3008049768 cites W1533955529 @default.
• W3008049768 cites W1566992315 @default.
• W3008049768 cites W1589138052 @default.
• W3008049768 cites W1599476759 @default.
• W3008049768 cites W1603555502 @default.
• W3008049768 cites W1701460655 @default.
• W3008049768 cites W1752964246 @default.
• W3008049768 cites W1777780029 @default.
• W3008049768 cites W185221403 @default.
• W3008049768 cites W1905727768 @default.
• W3008049768 cites W1967780926 @default.
• W3008049768 cites W1971054351 @default.
• W3008049768 cites W1974849608 @default.
• W3008049768 cites W1980143030 @default.
• W3008049768 cites W1980302281 @default.
• W3008049768 cites W1984594686 @default.
• W3008049768 cites W1984760454 @default.
• W3008049768 cites W1986558572 @default.
• W3008049768 cites W1987702283 @default.
• W3008049768 cites W1993163395 @default.
• W3008049768 cites W1995815488 @default.
• W3008049768 cites W1997910013 @default.
• W3008049768 cites W2000533324 @default.
• W3008049768 cites W2001480606 @default.
• W3008049768 cites W2001894281 @default.
• W3008049768 cites W2005262608 @default.
• W3008049768 cites W2005359428 @default.
• W3008049768 cites W2007799111 @default.
• W3008049768 cites W2009611937 @default.
• W3008049768 cites W2010466459 @default.
• W3008049768 cites W2010876644 @default.
• W3008049768 cites W2012279425 @default.
• W3008049768 cites W2012582733 @default.
• W3008049768 cites W2018251493 @default.
• W3008049768 cites W2020595428 @default.
• W3008049768 cites W2022372613 @default.
• W3008049768 cites W2025673880 @default.
• W3008049768 cites W2026618142 @default.
• W3008049768 cites W2026618323 @default.
• W3008049768 cites W2027397519 @default.
• W3008049768 cites W2029393588 @default.
• W3008049768 cites W2030955189 @default.
• W3008049768 cites W2034310945 @default.
• W3008049768 cites W2035033863 @default.
• W3008049768 cites W2035509260 @default.
• W3008049768 cites W2037299986 @default.
• W3008049768 cites W2038315656 @default.
• W3008049768 cites W2040073120 @default.
• W3008049768 cites W2040603998 @default.
• W3008049768 cites W2042433863 @default.
• W3008049768 cites W2043191762 @default.
• W3008049768 cites W2043240738 @default.
• W3008049768 cites W2052149521 @default.
• W3008049768 cites W2055620105 @default.
• W3008049768 cites W2060215176 @default.
• W3008049768 cites W2064711537 @default.
• W3008049768 cites W2067193640 @default.
• W3008049768 cites W2070463916 @default.
• W3008049768 cites W2071638524 @default.
• W3008049768 cites W2072253684 @default.
• W3008049768 cites W2072462631 @default.
• W3008049768 cites W2073420122 @default.
• W3008049768 cites W2073747620 @default.
• W3008049768 cites W2076853373 @default.
• W3008049768 cites W2078811876 @default.
• W3008049768 cites W2081020320 @default.
• W3008049768 cites W2081983232 @default.
• W3008049768 cites W2084148974 @default.
• W3008049768 cites W2085723401 @default.
• W3008049768 cites W2089907961 @default.
• W3008049768 cites W2094527424 @default.
• W3008049768 cites W2096030919 @default.
• W3008049768 cites W2096109794 @default.
• W3008049768 cites W2096328031 @default.
• W3008049768 cites W2097194409 @default.
• W3008049768 cites W2100155537 @default.
• W3008049768 cites W2104296367 @default.
• W3008049768 cites W2104357791 @default.
• W3008049768 cites W2104929047 @default.
• W3008049768 cites W2106890176 @default.
• W3008049768 cites W2107513655 @default.
• W3008049768 cites W2107986169 @default.
• W3008049768 cites W2108170307 @default.
• W3008049768 cites W2109457390 @default.
• W3008049768 cites W2110681223 @default.
• W3008049768 cites W2111058723 @default.
• W3008049768 cites W2111907482 @default.
• W3008049768 cites W2113080976 @default.

• next