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• W3008151606 abstract "Next-generation sequencing has revealed recurring somatic mutations in Waldenström macroglobulinemia (WM), including MYD88 (95%-97%), CXCR4 (30%-40%), ARID1A (17%), and CD79B (8%-15%). Deletions involving chromosome 6q are common in patients with mutated MYD88 and include genes that modulate NFKB, BCL2, Bruton tyrosine kinase (BTK), and apoptosis. Patients with wild-type MYD88 WM show an increased risk of transformation and death and exhibit many mutations found in diffuse large B-cell lymphoma. The discovery of MYD88 and CXCR4 mutations in WM has facilitated rational drug development, including the development of BTK and CXCR4 inhibitors. Responses to many agents commonly used to treat WM, including the BTK inhibitor ibrutinib, are affected by MYD88 and/or CXCR4 mutation status. The mutation status of both MYD88 and CXCR4 can be used for a precision-guided treatment approach to WM." @default.
• W3008151606 created "2020-03-06" @default.
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• W3008151606 date "2020-04-10" @default.
• W3008151606 modified "2023-10-03" @default.
• W3008151606 title "Genomic Landscape of Waldenström Macroglobulinemia and Its Impact on Treatment Strategies" @default.
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• W3008151606 cites W1917406824 @default.
• W3008151606 cites W1949051914 @default.
• W3008151606 cites W1963495263 @default.
• W3008151606 cites W1964337963 @default.
• W3008151606 cites W1966407423 @default.
• W3008151606 cites W1979816280 @default.
• W3008151606 cites W1985878057 @default.
• W3008151606 cites W1993211211 @default.
• W3008151606 cites W2006422013 @default.
• W3008151606 cites W2007851220 @default.
• W3008151606 cites W2017720810 @default.
• W3008151606 cites W2018830398 @default.
• W3008151606 cites W2031299149 @default.
• W3008151606 cites W2037983836 @default.
• W3008151606 cites W2039945582 @default.
• W3008151606 cites W2042887247 @default.
• W3008151606 cites W2050974188 @default.
• W3008151606 cites W2052855201 @default.
• W3008151606 cites W2057689314 @default.
• W3008151606 cites W2059048035 @default.
• W3008151606 cites W2061321423 @default.
• W3008151606 cites W2108120512 @default.
• W3008151606 cites W2116382435 @default.
• W3008151606 cites W2117309266 @default.
• W3008151606 cites W2133192145 @default.
• W3008151606 cites W2140380015 @default.
• W3008151606 cites W2148009655 @default.
• W3008151606 cites W2163579973 @default.
• W3008151606 cites W2167070743 @default.
• W3008151606 cites W2169209759 @default.
• W3008151606 cites W2194688567 @default.
• W3008151606 cites W2272261264 @default.
• W3008151606 cites W2274360660 @default.
• W3008151606 cites W2295816819 @default.
• W3008151606 cites W2337139592 @default.
• W3008151606 cites W2347186599 @default.
• W3008151606 cites W2510982931 @default.
• W3008151606 cites W2549946323 @default.
• W3008151606 cites W2556821739 @default.
• W3008151606 cites W2559715624 @default.
• W3008151606 cites W2560708148 @default.
• W3008151606 cites W2582696216 @default.
• W3008151606 cites W2588143355 @default.
• W3008151606 cites W2589965678 @default.
• W3008151606 cites W2591243927 @default.
• W3008151606 cites W2605207663 @default.
• W3008151606 cites W2742077769 @default.
• W3008151606 cites W2748189976 @default.
• W3008151606 cites W2762024848 @default.
• W3008151606 cites W2767092301 @default.
• W3008151606 cites W2769967822 @default.
• W3008151606 cites W2770121537 @default.
• W3008151606 cites W2784515202 @default.
• W3008151606 cites W2789573882 @default.
• W3008151606 cites W2790220378 @default.
• W3008151606 cites W2791428159 @default.
• W3008151606 cites W2794589961 @default.
• W3008151606 cites W2796163957 @default.
• W3008151606 cites W2799835249 @default.
• W3008151606 cites W2805689516 @default.
• W3008151606 cites W2809201980 @default.
• W3008151606 cites W2883521886 @default.
• W3008151606 cites W2884164278 @default.
• W3008151606 cites W2891048929 @default.
• W3008151606 cites W2898129912 @default.
• W3008151606 cites W2899509505 @default.
• W3008151606 cites W2900331532 @default.

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