FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3008302502> ?p ?o ?g. }

• W3008302502 endingPage "e0229105" @default.
• W3008302502 startingPage "e0229105" @default.
• W3008302502 abstract "Brain artery velocities (Time-Averaged Maximum Mean Velocity, TAMMV) by Transcranial Doppler (TCD), hematocrit, hemoglobin, Red blood cell (RBC) Distribution Width (RDW) and RBC rigidity index (Ri), when reported together with their correlations, provide a accurate and useful diagnostic picture than blood viscosity measurements alone. Additionally, our study included a sixth parameter provided by TCD, the Gosling Pulsatility Index PI, which is an indicator of CBF (Cerebral Blood Flow) resistance. All these parameters are routine in Hematology except for values of Ri. The rigidity (Ri) of the RBC is the main rheological characteristic of the blood of Sickle Cell Anemia (SCA) patients and several pathologies. However, its quantification depends on many commercial and experimental techniques, none disseminated and predominant around the World. The difference in absorbance values of the blood, during the process of sedimentation in a microwell of a Microplate Reader, is a straightforward way of semi-quantifying the RBC rigidity Ri, since the fraction of irreversibly sickled red blood cells does not form rouleaux. Erythrocyte Rigidity Index (Ri) was calculated using initial absorbance Ainitial (6 s) and final Afinal (540 s), Ri = 1 / (Ai-Af). The Ri of 119 patients (2-17 y / o, M & F) SCA, SCC (Sickle Cell/hemoglobin C), SCD (Sickle Cell/hemoglobin D), Sβ0thal (Sickle Cell/hemoglobin Beta Zero Thalassemia) and 71 blood donors (20-65 y / o, M & F) were measured in our laboratory while the five parameters (TAMMV and PI by TCD, Hct, Hb and RDW) were obtained from medical records. The in vitro addition of hydroxyurea (HU, 50mg /dl, n = 51 patients, and n = 8 healthy donors) in the samples decreased the rouleaux adhesion strength of both donor and patients' blood samples, leading to extraordinarily high Ri values. The correlation between the studied parameters was especially significant for the direct relationships between Ri, TAMMV, and PI." @default.
• W3008302502 created "2020-03-06" @default.
• W3008302502 creator A5027294628 @default.
• W3008302502 date "2020-02-21" @default.
• W3008302502 modified "2023-09-24" @default.
• W3008302502 title "An experimental erythrocyte rigidity index (Ri) and its correlations with Transcranial Doppler velocities (TAMMV), Gosling Pulsatility Index PI, hematocrit, hemoglobin concentration and red cell distribution width (RDW)" @default.
• W3008302502 cites W132623846 @default.
• W3008302502 cites W1464636291 @default.
• W3008302502 cites W1479795029 @default.
• W3008302502 cites W1505129168 @default.
• W3008302502 cites W152126388 @default.
• W3008302502 cites W1562502808 @default.
• W3008302502 cites W1755237470 @default.
• W3008302502 cites W179427535 @default.
• W3008302502 cites W180263266 @default.
• W3008302502 cites W1820998278 @default.
• W3008302502 cites W1885376530 @default.
• W3008302502 cites W1909908035 @default.
• W3008302502 cites W1944913561 @default.
• W3008302502 cites W1948831045 @default.
• W3008302502 cites W1950905025 @default.
• W3008302502 cites W1968242007 @default.
• W3008302502 cites W2008142857 @default.
• W3008302502 cites W2013449260 @default.
• W3008302502 cites W2017000541 @default.
• W3008302502 cites W2017248544 @default.
• W3008302502 cites W2026231954 @default.
• W3008302502 cites W2030514504 @default.
• W3008302502 cites W2041761249 @default.
• W3008302502 cites W2055527371 @default.
• W3008302502 cites W2064151279 @default.
• W3008302502 cites W2067381623 @default.
• W3008302502 cites W2069500475 @default.
• W3008302502 cites W2079352382 @default.
• W3008302502 cites W2085831998 @default.
• W3008302502 cites W2088409402 @default.
• W3008302502 cites W2094736181 @default.
• W3008302502 cites W2096365100 @default.
• W3008302502 cites W2101282585 @default.
• W3008302502 cites W2102715003 @default.
• W3008302502 cites W2104773315 @default.
• W3008302502 cites W2108149626 @default.
• W3008302502 cites W2110021778 @default.
• W3008302502 cites W2113012676 @default.
• W3008302502 cites W2119536526 @default.
• W3008302502 cites W2129911888 @default.
• W3008302502 cites W2130504981 @default.
• W3008302502 cites W2131427026 @default.
• W3008302502 cites W2141556236 @default.
• W3008302502 cites W2179417936 @default.
• W3008302502 cites W2179703994 @default.
• W3008302502 cites W2245247086 @default.
• W3008302502 cites W2287583773 @default.
• W3008302502 cites W2319975900 @default.
• W3008302502 cites W2397649431 @default.
• W3008302502 cites W2409143647 @default.
• W3008302502 cites W2411801115 @default.
• W3008302502 cites W2412174089 @default.
• W3008302502 cites W2418973446 @default.
• W3008302502 cites W2461583286 @default.
• W3008302502 cites W2561950855 @default.
• W3008302502 cites W2563389984 @default.
• W3008302502 cites W2779033317 @default.
• W3008302502 cites W2780004071 @default.
• W3008302502 cites W2780030094 @default.
• W3008302502 cites W2782582302 @default.
• W3008302502 cites W2783096356 @default.
• W3008302502 cites W2785012144 @default.
• W3008302502 cites W2787060755 @default.
• W3008302502 cites W2793937613 @default.
• W3008302502 cites W2794451252 @default.
• W3008302502 cites W2795454469 @default.
• W3008302502 cites W2803690536 @default.
• W3008302502 cites W2803896883 @default.
• W3008302502 cites W2811360094 @default.
• W3008302502 cites W2888600597 @default.
• W3008302502 cites W2889256977 @default.
• W3008302502 cites W2904284952 @default.
• W3008302502 cites W2921306274 @default.
• W3008302502 cites W2922156395 @default.
• W3008302502 cites W2947196840 @default.
• W3008302502 cites W2952495645 @default.
• W3008302502 cites W2968639311 @default.
• W3008302502 cites W635871684 @default.
• W3008302502 cites W64222769 @default.
• W3008302502 cites W656816774 @default.
• W3008302502 cites W4231020744 @default.
• W3008302502 doi "https://doi.org/10.1371/journal.pone.0229105" @default.
• W3008302502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7034921" @default.
• W3008302502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32084188" @default.
• W3008302502 hasPublicationYear "2020" @default.
• W3008302502 type Work @default.
• W3008302502 sameAs 3008302502 @default.
• W3008302502 citedByCount "7" @default.
• W3008302502 countsByYear W30083025022021 @default.
• W3008302502 countsByYear W30083025022022 @default.
• W3008302502 countsByYear W30083025022023 @default.
• W3008302502 crossrefType "journal-article" @default.

• next