Matches in SemOpenAlex for { <https://semopenalex.org/work/W3008335612> ?p ?o ?g. }
- W3008335612 endingPage "774" @default.
- W3008335612 startingPage "766" @default.
- W3008335612 abstract "In this study, the immune responses of Mesona chinensis Benth polysaccharides (MP) in vitro and in vivo were investigated. Results showed that MP presented immunomodulatory activities on macrophages and T lymphocytes in vitro. Compared with the cyclophosphamide (Cy)-induced immunosuppressive mice, the body weights, spleen indexes (3.45 to 4.91) and thymus indexes (0.78 to 1.04) of the mice treated with MP were increased, and the peripheral blood levels were recovered. MP treatment also increased superoxide dismutase, glutathione peroxidase and catalase activities, and reduced malondialdehyde levels to enhance the total antioxidant capacity of Cy-treated mice. In addition, MP significantly elevated IL-2, NO, and IFN-γ secretions of splenic lymphocytes and spleen, while MP mainly exerts an immune effect by regulating T lymphocytes. Furthermore, MP possessed the immunomodulatory activity by up-regulating the phosphorylation levels of proteins factors (c-Jun N-terminal kinase, extracellular regulated protein kinase and p38 kinase) in mitogen activated protein kinases signaling pathways. This study suggested that MP may be explored as a natural immune stimulant for functional food and nutraceutical industries." @default.
- W3008335612 created "2020-03-06" @default.
- W3008335612 creator A5013581237 @default.
- W3008335612 creator A5019336865 @default.
- W3008335612 creator A5049816813 @default.
- W3008335612 creator A5061163756 @default.
- W3008335612 creator A5072690064 @default.
- W3008335612 creator A5076120454 @default.
- W3008335612 creator A5081141964 @default.
- W3008335612 date "2020-06-01" @default.
- W3008335612 modified "2023-10-18" @default.
- W3008335612 title "Mesona chinensis Benth polysaccharides protect against oxidative stress and immunosuppression in cyclophosphamide-treated mice via MAPKs signal transduction pathways" @default.
- W3008335612 cites W1520501135 @default.
- W3008335612 cites W1962084025 @default.
- W3008335612 cites W1967028706 @default.
- W3008335612 cites W1982370376 @default.
- W3008335612 cites W1997413731 @default.
- W3008335612 cites W2008393191 @default.
- W3008335612 cites W2014276753 @default.
- W3008335612 cites W2018231290 @default.
- W3008335612 cites W2019484807 @default.
- W3008335612 cites W2055533912 @default.
- W3008335612 cites W2056163699 @default.
- W3008335612 cites W2059944922 @default.
- W3008335612 cites W2061309297 @default.
- W3008335612 cites W2062828091 @default.
- W3008335612 cites W2064244652 @default.
- W3008335612 cites W2065262677 @default.
- W3008335612 cites W2083054031 @default.
- W3008335612 cites W2091297811 @default.
- W3008335612 cites W2308159434 @default.
- W3008335612 cites W2351217592 @default.
- W3008335612 cites W2461583056 @default.
- W3008335612 cites W2565492693 @default.
- W3008335612 cites W2744010673 @default.
- W3008335612 cites W2744627957 @default.
- W3008335612 cites W2756303613 @default.
- W3008335612 cites W2771477087 @default.
- W3008335612 cites W2781798961 @default.
- W3008335612 cites W2804682477 @default.
- W3008335612 cites W2809928909 @default.
- W3008335612 cites W2884726198 @default.
- W3008335612 cites W2889091607 @default.
- W3008335612 cites W2893095853 @default.
- W3008335612 cites W2903362674 @default.
- W3008335612 cites W2906037308 @default.
- W3008335612 cites W2914047343 @default.
- W3008335612 cites W2955941613 @default.
- W3008335612 cites W2967936607 @default.
- W3008335612 cites W2991245735 @default.
- W3008335612 cites W4242862437 @default.
- W3008335612 doi "https://doi.org/10.1016/j.ijbiomac.2020.02.318" @default.
- W3008335612 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32119945" @default.
- W3008335612 hasPublicationYear "2020" @default.
- W3008335612 type Work @default.
- W3008335612 sameAs 3008335612 @default.
- W3008335612 citedByCount "44" @default.
- W3008335612 countsByYear W30083356122020 @default.
- W3008335612 countsByYear W30083356122021 @default.
- W3008335612 countsByYear W30083356122022 @default.
- W3008335612 countsByYear W30083356122023 @default.
- W3008335612 crossrefType "journal-article" @default.
- W3008335612 hasAuthorship W3008335612A5013581237 @default.
- W3008335612 hasAuthorship W3008335612A5019336865 @default.
- W3008335612 hasAuthorship W3008335612A5049816813 @default.
- W3008335612 hasAuthorship W3008335612A5061163756 @default.
- W3008335612 hasAuthorship W3008335612A5072690064 @default.
- W3008335612 hasAuthorship W3008335612A5076120454 @default.
- W3008335612 hasAuthorship W3008335612A5081141964 @default.
- W3008335612 hasConcept C100817775 @default.
- W3008335612 hasConcept C185592680 @default.
- W3008335612 hasConcept C203014093 @default.
- W3008335612 hasConcept C2776151105 @default.
- W3008335612 hasConcept C2776694085 @default.
- W3008335612 hasConcept C2776755627 @default.
- W3008335612 hasConcept C2780252810 @default.
- W3008335612 hasConcept C54355233 @default.
- W3008335612 hasConcept C55493867 @default.
- W3008335612 hasConcept C62478195 @default.
- W3008335612 hasConcept C86803240 @default.
- W3008335612 hasConcept C95444343 @default.
- W3008335612 hasConceptScore W3008335612C100817775 @default.
- W3008335612 hasConceptScore W3008335612C185592680 @default.
- W3008335612 hasConceptScore W3008335612C203014093 @default.
- W3008335612 hasConceptScore W3008335612C2776151105 @default.
- W3008335612 hasConceptScore W3008335612C2776694085 @default.
- W3008335612 hasConceptScore W3008335612C2776755627 @default.
- W3008335612 hasConceptScore W3008335612C2780252810 @default.
- W3008335612 hasConceptScore W3008335612C54355233 @default.
- W3008335612 hasConceptScore W3008335612C55493867 @default.
- W3008335612 hasConceptScore W3008335612C62478195 @default.
- W3008335612 hasConceptScore W3008335612C86803240 @default.
- W3008335612 hasConceptScore W3008335612C95444343 @default.
- W3008335612 hasFunder F4320321001 @default.
- W3008335612 hasFunder F4320322665 @default.
- W3008335612 hasFunder F4320322792 @default.
- W3008335612 hasLocation W30083356121 @default.
- W3008335612 hasOpenAccess W3008335612 @default.