Matches in SemOpenAlex for { <https://semopenalex.org/work/W3008479530> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W3008479530 endingPage "S216" @default.
- W3008479530 startingPage "S215" @default.
- W3008479530 abstract "Contrast-induced acute kidney injury (CI-AKI) is one of the leading causes of acute kidney injury. Trimetazidine (TMZ) is a type of anti-ischemic drug developed in recent year. Available data on the renal effects showed TMZ can significantly reduce the incidence of (CI-AKI). We conducted this systematic review and meta-analysis of clinical trials that investigated the clinical effect of TMZ on the prevention of CIN in patients with renal insufficiency patients undergoing percutaneous coronary intervention. This meta-analysis was conducted and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA). A search of the Medline, Cochrane and Google Scholar databases were conducted independently by two researchers for randomized controlled trials comparing TMZ versus conventional hydration alone for the prevention of CIN. The relative risk (RR) was estimated with a 95% confidence interval (CI). Heterogeneity was reported with the I2 statistic, using a fixed-effects model, and >50% of I2 was considered to be statistically significant. All statistical analyses were performed using STATA software, version 12.0. 11 studies met our inclusion/exclusion criteria including 1611 patients: 797 undergoing TMZ plus hydration and 814 controls (hydration only). Heterogeneity of each study was low, I2 = 0%, P = 0.747. The incidence of CIN in the TMZ plus hydration group was 6.0% (48/797) and the incidence of CIN in the control (hydration) group was 20.6% (168/814). A pooled analysis for all studies showed that TMZ can significantly reduce the incidence of CIN AKI compared to saline alone (relative risk 0.35, 95% confidence interval [CI] 0.25, 0.48, P = 0.000). Present systematic review and meta-analysis by combining data from 11 studies showed Trimetazidine can effectively protect renal function and reducing the incidence of CIN in patients undergoing coronary angiography." @default.
- W3008479530 created "2020-03-06" @default.
- W3008479530 creator A5019625787 @default.
- W3008479530 creator A5037258527 @default.
- W3008479530 creator A5058110432 @default.
- W3008479530 creator A5070409721 @default.
- W3008479530 creator A5075881304 @default.
- W3008479530 creator A5077690677 @default.
- W3008479530 creator A5087033286 @default.
- W3008479530 date "2020-03-01" @default.
- W3008479530 modified "2023-10-14" @default.
- W3008479530 title "Abstract No. 488 Trimetazidine in the prevention of contrast-induced nephropathy in patients with renal insufficiency undergoing percutaneous coronary intervention: a systematic review and meta-analysis" @default.
- W3008479530 doi "https://doi.org/10.1016/j.jvir.2019.12.549" @default.
- W3008479530 hasPublicationYear "2020" @default.
- W3008479530 type Work @default.
- W3008479530 sameAs 3008479530 @default.
- W3008479530 citedByCount "0" @default.
- W3008479530 crossrefType "journal-article" @default.
- W3008479530 hasAuthorship W3008479530A5019625787 @default.
- W3008479530 hasAuthorship W3008479530A5037258527 @default.
- W3008479530 hasAuthorship W3008479530A5058110432 @default.
- W3008479530 hasAuthorship W3008479530A5070409721 @default.
- W3008479530 hasAuthorship W3008479530A5075881304 @default.
- W3008479530 hasAuthorship W3008479530A5077690677 @default.
- W3008479530 hasAuthorship W3008479530A5087033286 @default.
- W3008479530 hasBestOaLocation W30084795301 @default.
- W3008479530 hasConcept C120665830 @default.
- W3008479530 hasConcept C121332964 @default.
- W3008479530 hasConcept C126322002 @default.
- W3008479530 hasConcept C134018914 @default.
- W3008479530 hasConcept C141071460 @default.
- W3008479530 hasConcept C142724271 @default.
- W3008479530 hasConcept C168563851 @default.
- W3008479530 hasConcept C17744445 @default.
- W3008479530 hasConcept C189708586 @default.
- W3008479530 hasConcept C199539241 @default.
- W3008479530 hasConcept C204787440 @default.
- W3008479530 hasConcept C2777596629 @default.
- W3008479530 hasConcept C2777927741 @default.
- W3008479530 hasConcept C2778569047 @default.
- W3008479530 hasConcept C2779473830 @default.
- W3008479530 hasConcept C2780400711 @default.
- W3008479530 hasConcept C2780472472 @default.
- W3008479530 hasConcept C2781184683 @default.
- W3008479530 hasConcept C44249647 @default.
- W3008479530 hasConcept C500558357 @default.
- W3008479530 hasConcept C555293320 @default.
- W3008479530 hasConcept C61511704 @default.
- W3008479530 hasConcept C71924100 @default.
- W3008479530 hasConcept C95190672 @default.
- W3008479530 hasConceptScore W3008479530C120665830 @default.
- W3008479530 hasConceptScore W3008479530C121332964 @default.
- W3008479530 hasConceptScore W3008479530C126322002 @default.
- W3008479530 hasConceptScore W3008479530C134018914 @default.
- W3008479530 hasConceptScore W3008479530C141071460 @default.
- W3008479530 hasConceptScore W3008479530C142724271 @default.
- W3008479530 hasConceptScore W3008479530C168563851 @default.
- W3008479530 hasConceptScore W3008479530C17744445 @default.
- W3008479530 hasConceptScore W3008479530C189708586 @default.
- W3008479530 hasConceptScore W3008479530C199539241 @default.
- W3008479530 hasConceptScore W3008479530C204787440 @default.
- W3008479530 hasConceptScore W3008479530C2777596629 @default.
- W3008479530 hasConceptScore W3008479530C2777927741 @default.
- W3008479530 hasConceptScore W3008479530C2778569047 @default.
- W3008479530 hasConceptScore W3008479530C2779473830 @default.
- W3008479530 hasConceptScore W3008479530C2780400711 @default.
- W3008479530 hasConceptScore W3008479530C2780472472 @default.
- W3008479530 hasConceptScore W3008479530C2781184683 @default.
- W3008479530 hasConceptScore W3008479530C44249647 @default.
- W3008479530 hasConceptScore W3008479530C500558357 @default.
- W3008479530 hasConceptScore W3008479530C555293320 @default.
- W3008479530 hasConceptScore W3008479530C61511704 @default.
- W3008479530 hasConceptScore W3008479530C71924100 @default.
- W3008479530 hasConceptScore W3008479530C95190672 @default.
- W3008479530 hasIssue "3" @default.
- W3008479530 hasLocation W30084795301 @default.
- W3008479530 hasOpenAccess W3008479530 @default.
- W3008479530 hasPrimaryLocation W30084795301 @default.
- W3008479530 hasRelatedWork W2019927856 @default.
- W3008479530 hasRelatedWork W2020579547 @default.
- W3008479530 hasRelatedWork W2021100442 @default.
- W3008479530 hasRelatedWork W2298774464 @default.
- W3008479530 hasRelatedWork W2310809385 @default.
- W3008479530 hasRelatedWork W2361438705 @default.
- W3008479530 hasRelatedWork W3133194408 @default.
- W3008479530 hasRelatedWork W3192748141 @default.
- W3008479530 hasRelatedWork W4205726400 @default.
- W3008479530 hasRelatedWork W4220787562 @default.
- W3008479530 hasVolume "31" @default.
- W3008479530 isParatext "false" @default.
- W3008479530 isRetracted "false" @default.
- W3008479530 magId "3008479530" @default.
- W3008479530 workType "article" @default.