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- W3008601661 abstract "Human saliva is a complex mixture of fluids considered to have a real potential in maintaining the dental health, carrying out important functions in the local modulation of inflammatory reactions and immune response. The biologic properties of salivary alpha-amylase are a subject of intense debate in the scientific literature, regarding its use as a biomarker for local and systemic diseases, including caries lesions. The purpose of our study was to measure the correlation between the salivary level of alpha-amylase and the incidence of caries in a group of children with young permanent teeth. A total of 128 participants were included in four study groups according to presence or absence of dental caries, based on specific inclusion/exclusion criteria and a scoring system between 0-5, depending on gender and the number of caries lesions. From each patient, 10 mL of saliva was collected and examined with a spectrophotometer in order to determine the level of salivary alpha-amylase. The collected data were statistically analyzed with the GraphPad Prism 7.03 and Mann-Whitneytest, a value of p [0.05 being considered statistically significant. Our results showed that caries active children had higher levels of salivary enzyme compared to caries free groups (p=0.001). Therefore, we concluded that salivary alpha-amylase can be considered a biomarker for the prognosis of dental caries development, offering new perspectives for preventive dentistry." @default.
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- W3008601661 date "2018-01-15" @default.
- W3008601661 modified "2023-10-16" @default.
- W3008601661 title "Correlation Between the Salivary Level of Alpha-amylase and the Risk for Dental Caries in Young Permanent Teeth" @default.
- W3008601661 doi "https://doi.org/10.37358/rc.17.12.6022" @default.
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