FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3008838938> ?p ?o ?g. }

• W3008838938 endingPage "531" @default.
• W3008838938 startingPage "521" @default.
• W3008838938 abstract "Donation after circulatory determination of death (DCD) has been performed in Canada since 2006. Numerous aspects of donor management remain controversial. We performed a multicentre cohort study involving potential DCD donors in western Canada (2008–2017), as well as recipients of their organs, to describe donor characteristics and critical care practices, and their relation to one-year recipient and graft survival. There were 257 patients in four provinces that underwent withdrawal of life-sustaining therapies (WLST) in anticipation of possible DCD. The proportion of patients that died within two hours of WLST ranged from 67% to 88% across provinces (P = 0.06), and was predicted by deeper coma (P = 0.01), loss of pupillary light or corneal reflexes (P = 0.02), and vasopressor use (P = 0.01). There were significant differences between provinces in time intervals from onset of hypotension to death (9–11 min; P = 0.02) and death to vascular cannulation (7–10 min; P < 0.001). There was inconsistency in pre-mortem heparin administration (82–96%; P = 0.03), including timing (before vs after WLST; P < 0.001) and dose (≥ 300 vs < 300 units·kg−1; P < 0.001). Donation after circulatory death provided organs for 321 kidney, 81 liver, and 50 lung transplants. One-year recipient and graft survival did not differ among provinces (range 85–90%, P = 0.45). Predictors of death or graft failure included older recipient age (odds ratio [OR] per year, 1.04; 95% confidence interval [CI],1.01 to 1.07) and male donor sex (OR, 3.35; 95% CI, 1.39 to 8.09), but not time intervals between WLST and cannulation or practices related to heparin use. There is significant variability in critical care DCD practices in western Canada, but this has not resulted in significant differences in recipient or graft survival. Further research is required to guide optimal management of potential DCD donors." @default.
• W3008838938 created "2020-03-06" @default.
• W3008838938 creator A5007132916 @default.
• W3008838938 creator A5020473629 @default.
• W3008838938 creator A5028486724 @default.
• W3008838938 creator A5052459990 @default.
• W3008838938 creator A5059982441 @default.
• W3008838938 creator A5063376494 @default.
• W3008838938 creator A5073826536 @default.
• W3008838938 creator A5085254991 @default.
• W3008838938 creator A5085334380 @default.
• W3008838938 date "2020-02-25" @default.
• W3008838938 modified "2023-10-15" @default.
• W3008838938 title "Donation after circulatory determination of death in western Canada: a multicentre study of donor characteristics and critical care practices" @default.
• W3008838938 cites W1481319095 @default.
• W3008838938 cites W1525452866 @default.
• W3008838938 cites W1549883515 @default.
• W3008838938 cites W1885794135 @default.
• W3008838938 cites W1991458519 @default.
• W3008838938 cites W1992015703 @default.
• W3008838938 cites W1995811873 @default.
• W3008838938 cites W2000099999 @default.
• W3008838938 cites W2020718377 @default.
• W3008838938 cites W2021466247 @default.
• W3008838938 cites W2027637955 @default.
• W3008838938 cites W2035974810 @default.
• W3008838938 cites W2073031159 @default.
• W3008838938 cites W2078431360 @default.
• W3008838938 cites W2095739945 @default.
• W3008838938 cites W2096453556 @default.
• W3008838938 cites W2110538883 @default.
• W3008838938 cites W2113894435 @default.
• W3008838938 cites W2124097348 @default.
• W3008838938 cites W2143906500 @default.
• W3008838938 cites W2149143601 @default.
• W3008838938 cites W2152902252 @default.
• W3008838938 cites W2153902346 @default.
• W3008838938 cites W2155619745 @default.
• W3008838938 cites W2157764130 @default.
• W3008838938 cites W2171861032 @default.
• W3008838938 cites W2212848986 @default.
• W3008838938 cites W2229998871 @default.
• W3008838938 cites W2314968400 @default.
• W3008838938 cites W2327835357 @default.
• W3008838938 cites W232811114 @default.
• W3008838938 cites W2342063582 @default.
• W3008838938 cites W2506077334 @default.
• W3008838938 cites W2572825480 @default.
• W3008838938 cites W2743302194 @default.
• W3008838938 cites W2744511866 @default.
• W3008838938 cites W2754699822 @default.
• W3008838938 cites W2762451948 @default.
• W3008838938 cites W2764019021 @default.
• W3008838938 cites W2777885923 @default.
• W3008838938 cites W2793477202 @default.
• W3008838938 cites W2794303250 @default.
• W3008838938 cites W2808092861 @default.
• W3008838938 cites W2810031306 @default.
• W3008838938 cites W2885324571 @default.
• W3008838938 cites W2892140255 @default.
• W3008838938 cites W2955390344 @default.
• W3008838938 doi "https://doi.org/10.1007/s12630-020-01594-8" @default.
• W3008838938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32100271" @default.
• W3008838938 hasPublicationYear "2020" @default.
• W3008838938 type Work @default.
• W3008838938 sameAs 3008838938 @default.
• W3008838938 citedByCount "6" @default.
• W3008838938 countsByYear W30088389382021 @default.
• W3008838938 countsByYear W30088389382022 @default.
• W3008838938 crossrefType "journal-article" @default.
• W3008838938 hasAuthorship W3008838938A5007132916 @default.
• W3008838938 hasAuthorship W3008838938A5020473629 @default.
• W3008838938 hasAuthorship W3008838938A5028486724 @default.
• W3008838938 hasAuthorship W3008838938A5052459990 @default.
• W3008838938 hasAuthorship W3008838938A5059982441 @default.
• W3008838938 hasAuthorship W3008838938A5063376494 @default.
• W3008838938 hasAuthorship W3008838938A5073826536 @default.
• W3008838938 hasAuthorship W3008838938A5085254991 @default.
• W3008838938 hasAuthorship W3008838938A5085334380 @default.
• W3008838938 hasBestOaLocation W30088389381 @default.
• W3008838938 hasConcept C126322002 @default.
• W3008838938 hasConcept C141071460 @default.
• W3008838938 hasConcept C17744445 @default.
• W3008838938 hasConcept C177713679 @default.
• W3008838938 hasConcept C199539241 @default.
• W3008838938 hasConcept C2775933685 @default.
• W3008838938 hasConcept C2911091166 @default.
• W3008838938 hasConcept C2994510829 @default.
• W3008838938 hasConcept C512399662 @default.
• W3008838938 hasConcept C71924100 @default.
• W3008838938 hasConcept C72859922 @default.
• W3008838938 hasConcept C74909509 @default.
• W3008838938 hasConceptScore W3008838938C126322002 @default.
• W3008838938 hasConceptScore W3008838938C141071460 @default.
• W3008838938 hasConceptScore W3008838938C17744445 @default.
• W3008838938 hasConceptScore W3008838938C177713679 @default.
• W3008838938 hasConceptScore W3008838938C199539241 @default.
• W3008838938 hasConceptScore W3008838938C2775933685 @default.

• next