Matches in SemOpenAlex for { <https://semopenalex.org/work/W3008883061> ?p ?o ?g. }
- W3008883061 endingPage "862" @default.
- W3008883061 startingPage "851" @default.
- W3008883061 abstract "Background Medication overuse headache may be associated with widespread alterations along the thalamocortical pathway, a pathway involved in pain perception and disease progression. This study addressed whether brain metabolites in key regions of the thalamocortical pathway differed between chronic migraine patients with medication overuse headache and without medication overuse headache. Methods Magnetic resonance spectroscopic imaging was used to map metabolites in the bilateral anterior cingulate cortices, mid cingulate cortices, posterior cingulate cortices, and the thalami. Sixteen patients with medication overuse headache were compared with 16 matched patients without medication overuse headache and 16 matched healthy controls. Results Glutamate and glutamine in the right mid cingulate cortex and myo-inositol in the left anterior cingulate cortex were significantly higher in patients with medication overuse headache than patients without medication overuse headache, but similar to healthy controls. Both patient groups exhibited reduced N-acetyl-aspartate and creatine in the thalamus, reduced myo-inositol in the right anterior cingulate cortex, and elevated choline in the right mid cingulate cortex. Finally, a negative association between myo-inositol laterality index in the anterior cingulate cortices and number of days per month with acute medication use was found across all patients. Conclusions Patients with medication overuse headache were characterized by a distinct concentration profile of myo-inositol, a glial marker, in the anterior cingulate cortices that may have arisen from medication overuse and could contribute to the development of medication overuse headache." @default.
- W3008883061 created "2020-03-06" @default.
- W3008883061 creator A5002366827 @default.
- W3008883061 creator A5011714510 @default.
- W3008883061 creator A5028390017 @default.
- W3008883061 creator A5046226377 @default.
- W3008883061 creator A5065378579 @default.
- W3008883061 creator A5076377762 @default.
- W3008883061 creator A5077941592 @default.
- W3008883061 date "2020-02-25" @default.
- W3008883061 modified "2023-10-16" @default.
- W3008883061 title "Brain metabolites in chronic migraine patients with medication overuse headache" @default.
- W3008883061 cites W1557128794 @default.
- W3008883061 cites W1730237872 @default.
- W3008883061 cites W1965616302 @default.
- W3008883061 cites W1974140259 @default.
- W3008883061 cites W1994958750 @default.
- W3008883061 cites W1995772795 @default.
- W3008883061 cites W2003334995 @default.
- W3008883061 cites W2005793755 @default.
- W3008883061 cites W2019412391 @default.
- W3008883061 cites W2025265926 @default.
- W3008883061 cites W2052065888 @default.
- W3008883061 cites W2052257423 @default.
- W3008883061 cites W2062780545 @default.
- W3008883061 cites W2067594397 @default.
- W3008883061 cites W2068277231 @default.
- W3008883061 cites W2083956595 @default.
- W3008883061 cites W2093037844 @default.
- W3008883061 cites W2098351223 @default.
- W3008883061 cites W2100970347 @default.
- W3008883061 cites W2103585815 @default.
- W3008883061 cites W2114287861 @default.
- W3008883061 cites W2115845435 @default.
- W3008883061 cites W2119673091 @default.
- W3008883061 cites W2121701181 @default.
- W3008883061 cites W2123407155 @default.
- W3008883061 cites W2129662663 @default.
- W3008883061 cites W2139601688 @default.
- W3008883061 cites W2142885260 @default.
- W3008883061 cites W2149389932 @default.
- W3008883061 cites W2160202859 @default.
- W3008883061 cites W2165965671 @default.
- W3008883061 cites W2171411074 @default.
- W3008883061 cites W2171782286 @default.
- W3008883061 cites W2210733569 @default.
- W3008883061 cites W2301669941 @default.
- W3008883061 cites W2426802935 @default.
- W3008883061 cites W2530028960 @default.
- W3008883061 cites W2591241471 @default.
- W3008883061 cites W2626500574 @default.
- W3008883061 cites W2773101811 @default.
- W3008883061 cites W2783706608 @default.
- W3008883061 cites W2885795764 @default.
- W3008883061 doi "https://doi.org/10.1177/0333102420908579" @default.
- W3008883061 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32098478" @default.
- W3008883061 hasPublicationYear "2020" @default.
- W3008883061 type Work @default.
- W3008883061 sameAs 3008883061 @default.
- W3008883061 citedByCount "7" @default.
- W3008883061 countsByYear W30088830612020 @default.
- W3008883061 countsByYear W30088830612021 @default.
- W3008883061 countsByYear W30088830612022 @default.
- W3008883061 countsByYear W30088830612023 @default.
- W3008883061 crossrefType "journal-article" @default.
- W3008883061 hasAuthorship W3008883061A5002366827 @default.
- W3008883061 hasAuthorship W3008883061A5011714510 @default.
- W3008883061 hasAuthorship W3008883061A5028390017 @default.
- W3008883061 hasAuthorship W3008883061A5046226377 @default.
- W3008883061 hasAuthorship W3008883061A5065378579 @default.
- W3008883061 hasAuthorship W3008883061A5076377762 @default.
- W3008883061 hasAuthorship W3008883061A5077941592 @default.
- W3008883061 hasConcept C118552586 @default.
- W3008883061 hasConcept C126322002 @default.
- W3008883061 hasConcept C169900460 @default.
- W3008883061 hasConcept C2778402161 @default.
- W3008883061 hasConcept C2778541695 @default.
- W3008883061 hasConcept C2778733324 @default.
- W3008883061 hasConcept C2779896295 @default.
- W3008883061 hasConcept C2781123555 @default.
- W3008883061 hasConcept C2781210436 @default.
- W3008883061 hasConcept C42219234 @default.
- W3008883061 hasConcept C529278444 @default.
- W3008883061 hasConcept C71924100 @default.
- W3008883061 hasConceptScore W3008883061C118552586 @default.
- W3008883061 hasConceptScore W3008883061C126322002 @default.
- W3008883061 hasConceptScore W3008883061C169900460 @default.
- W3008883061 hasConceptScore W3008883061C2778402161 @default.
- W3008883061 hasConceptScore W3008883061C2778541695 @default.
- W3008883061 hasConceptScore W3008883061C2778733324 @default.
- W3008883061 hasConceptScore W3008883061C2779896295 @default.
- W3008883061 hasConceptScore W3008883061C2781123555 @default.
- W3008883061 hasConceptScore W3008883061C2781210436 @default.
- W3008883061 hasConceptScore W3008883061C42219234 @default.
- W3008883061 hasConceptScore W3008883061C529278444 @default.
- W3008883061 hasConceptScore W3008883061C71924100 @default.
- W3008883061 hasFunder F4320322795 @default.
- W3008883061 hasIssue "8" @default.