Matches in SemOpenAlex for { <https://semopenalex.org/work/W3009179985> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W3009179985 abstract "While epidemiological studies have clearly documented that smoking cessation significantly enhances sexual health, the underlying mechanism remains largely unknown. Thus, we wished to explore possible mechanisms by using a rat model of smoking-associated erectile dysfunction (ED).Forty 8-week old male Sprague-Dawley rats were divided into 4 groups. Ten rats were exposed only to room air (N group). The remaining 30 rats were passively exposed to cigarette smoke over a 12-week period. At the end of 12 weeks, the smoking (S, n=10) group underwent immediate erectile function testing and were sacrificed. The remaining 20 rats were exposed to room air only for 4 (Q4W, n=10) or 8 (Q8W, n=10) weeks and then underwent erectile function testing and sacrifice. Erectile function was evaluated by measuring intracavernous pressure (ICP) and mean arterial pressure (MAP). After blood collection for serum testosterone determination, rats were sacrificed to obtain corporal tissue for immunohistochemistry.Mean ICP/MAP ratio was significantly lower in the S group compared to the N and Q8W groups (0.52±0.11, 0.94±0.05, and 0.94±0.12, respectively, P=0.0189). Smooth muscle/collagen ratio was also significantly lower in the S group compared to the N and Q8W groups (11.8±0.94, 17.5±1.82, and 16.4±0.60, respectively, P=0.0008). Oxidative stress and apoptotic indices were significantly higher in the S group compared to the N and Q8W groups. Neuronal and endothelial nitric oxide synthases were significantly less expressed in the S group compared to the N and Q8W groups.Smoking cessation is associated with partial recovery of penile hemodynamics in a rat model of smoking associated ED." @default.
- W3009179985 created "2020-03-13" @default.
- W3009179985 creator A5017842008 @default.
- W3009179985 creator A5036873753 @default.
- W3009179985 creator A5053487335 @default.
- W3009179985 creator A5081135852 @default.
- W3009179985 creator A5084703000 @default.
- W3009179985 creator A5091683814 @default.
- W3009179985 date "2020-04-01" @default.
- W3009179985 modified "2023-10-09" @default.
- W3009179985 title "The influence of smoking exposure and cessation on penile hemodynamics and corporal tissue in a rat model" @default.
- W3009179985 cites W1605698794 @default.
- W3009179985 cites W1832887128 @default.
- W3009179985 cites W1973277708 @default.
- W3009179985 cites W1979246926 @default.
- W3009179985 cites W1981695960 @default.
- W3009179985 cites W2025002838 @default.
- W3009179985 cites W2025091316 @default.
- W3009179985 cites W2046791050 @default.
- W3009179985 cites W2052605813 @default.
- W3009179985 cites W2054464960 @default.
- W3009179985 cites W2063031295 @default.
- W3009179985 cites W2104659325 @default.
- W3009179985 cites W2114099957 @default.
- W3009179985 cites W2145898975 @default.
- W3009179985 cites W2157303036 @default.
- W3009179985 cites W2157784579 @default.
- W3009179985 cites W2205500978 @default.
- W3009179985 cites W2226440260 @default.
- W3009179985 cites W2411260586 @default.
- W3009179985 cites W2884841306 @default.
- W3009179985 cites W2939116553 @default.
- W3009179985 doi "https://doi.org/10.21037/tau.2019.12.45" @default.
- W3009179985 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7215033" @default.
- W3009179985 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32420170" @default.
- W3009179985 hasPublicationYear "2020" @default.
- W3009179985 type Work @default.
- W3009179985 sameAs 3009179985 @default.
- W3009179985 citedByCount "0" @default.
- W3009179985 crossrefType "journal-article" @default.
- W3009179985 hasAuthorship W3009179985A5017842008 @default.
- W3009179985 hasAuthorship W3009179985A5036873753 @default.
- W3009179985 hasAuthorship W3009179985A5053487335 @default.
- W3009179985 hasAuthorship W3009179985A5081135852 @default.
- W3009179985 hasAuthorship W3009179985A5084703000 @default.
- W3009179985 hasAuthorship W3009179985A5091683814 @default.
- W3009179985 hasBestOaLocation W30091799851 @default.
- W3009179985 hasConcept C126322002 @default.
- W3009179985 hasConcept C126894567 @default.
- W3009179985 hasConcept C134018914 @default.
- W3009179985 hasConcept C142724271 @default.
- W3009179985 hasConcept C204232928 @default.
- W3009179985 hasConcept C2776151105 @default.
- W3009179985 hasConcept C2776452961 @default.
- W3009179985 hasConcept C2777843972 @default.
- W3009179985 hasConcept C2777953023 @default.
- W3009179985 hasConcept C2779279991 @default.
- W3009179985 hasConcept C2779929075 @default.
- W3009179985 hasConcept C3020768380 @default.
- W3009179985 hasConcept C519581460 @default.
- W3009179985 hasConcept C71924100 @default.
- W3009179985 hasConcept C84393581 @default.
- W3009179985 hasConceptScore W3009179985C126322002 @default.
- W3009179985 hasConceptScore W3009179985C126894567 @default.
- W3009179985 hasConceptScore W3009179985C134018914 @default.
- W3009179985 hasConceptScore W3009179985C142724271 @default.
- W3009179985 hasConceptScore W3009179985C204232928 @default.
- W3009179985 hasConceptScore W3009179985C2776151105 @default.
- W3009179985 hasConceptScore W3009179985C2776452961 @default.
- W3009179985 hasConceptScore W3009179985C2777843972 @default.
- W3009179985 hasConceptScore W3009179985C2777953023 @default.
- W3009179985 hasConceptScore W3009179985C2779279991 @default.
- W3009179985 hasConceptScore W3009179985C2779929075 @default.
- W3009179985 hasConceptScore W3009179985C3020768380 @default.
- W3009179985 hasConceptScore W3009179985C519581460 @default.
- W3009179985 hasConceptScore W3009179985C71924100 @default.
- W3009179985 hasConceptScore W3009179985C84393581 @default.
- W3009179985 hasLocation W30091799851 @default.
- W3009179985 hasLocation W30091799852 @default.
- W3009179985 hasLocation W30091799853 @default.
- W3009179985 hasLocation W30091799854 @default.
- W3009179985 hasOpenAccess W3009179985 @default.
- W3009179985 hasPrimaryLocation W30091799851 @default.
- W3009179985 hasRelatedWork W1769405 @default.
- W3009179985 hasRelatedWork W1826144 @default.
- W3009179985 hasRelatedWork W19007557 @default.
- W3009179985 hasRelatedWork W20888346 @default.
- W3009179985 hasRelatedWork W3469162 @default.
- W3009179985 hasRelatedWork W5216414 @default.
- W3009179985 hasRelatedWork W6289121 @default.
- W3009179985 hasRelatedWork W8761671 @default.
- W3009179985 hasRelatedWork W3618855 @default.
- W3009179985 hasRelatedWork W7458153 @default.
- W3009179985 isParatext "false" @default.
- W3009179985 isRetracted "false" @default.
- W3009179985 magId "3009179985" @default.
- W3009179985 workType "article" @default.