FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3009219785> ?p ?o ?g. }

• W3009219785 endingPage "413" @default.
• W3009219785 startingPage "413" @default.
• W3009219785 abstract "When a biomaterial is inserted into the body, proteins rapidly adsorb onto its surface, creating a conditioning protein film that functions as a link between the implant and adhering cells. Depending on the nano-roughness of the surface, proteins will adsorb in different amounts, with different conformations and orientations, possibly affecting the subsequent attachment of cells to the surface. Thus, modifications of the surface nanotopography of an implant may prevent biomaterial-associated infections. Fibrinogen is of particular importance since it contains adhesion epitopes that are recognized by both eukaryotic and prokaryotic cells, and can therefore influence the adhesion of bacteria. The aim of this study was to model adsorption of fibrinogen to smooth or nanostructured silica surfaces in an attempt to further understand how surface nanotopography may affect the orientation of the adsorbed fibrinogen molecule. We used a coarse-grained model, where the main body of fibrinogen (visible in the crystal structure) was modeled as rigid and the flexible α C-chains (not visible in the crystal structure) were modeled as completely disordered. We found that the elongated fibrinogen molecule preferably adsorbs in such a way that it protrudes further into solution on a nanostructured surface compared to a flat one. This implicates that the orientation on the flat surface increases its bio-availability." @default.
• W3009219785 created "2020-03-13" @default.
• W3009219785 creator A5029272165 @default.
• W3009219785 creator A5077671600 @default.
• W3009219785 creator A5085372653 @default.
• W3009219785 creator A5085509801 @default.
• W3009219785 date "2020-03-06" @default.
• W3009219785 modified "2023-10-17" @default.
• W3009219785 title "Adsorption of Fibrinogen on Silica Surfaces—The Effect of Attached Nanoparticles" @default.
• W3009219785 cites W1588491159 @default.
• W3009219785 cites W1890755677 @default.
• W3009219785 cites W1937449799 @default.
• W3009219785 cites W1966585852 @default.
• W3009219785 cites W1967993465 @default.
• W3009219785 cites W1976920225 @default.
• W3009219785 cites W1981054366 @default.
• W3009219785 cites W1992137484 @default.
• W3009219785 cites W1997961076 @default.
• W3009219785 cites W2012312363 @default.
• W3009219785 cites W2015642465 @default.
• W3009219785 cites W2015646772 @default.
• W3009219785 cites W2017971895 @default.
• W3009219785 cites W2019189605 @default.
• W3009219785 cites W2023960215 @default.
• W3009219785 cites W2028805384 @default.
• W3009219785 cites W2036374139 @default.
• W3009219785 cites W2047838167 @default.
• W3009219785 cites W2048278752 @default.
• W3009219785 cites W2056760934 @default.
• W3009219785 cites W2057547090 @default.
• W3009219785 cites W2064724563 @default.
• W3009219785 cites W2065321239 @default.
• W3009219785 cites W2067230558 @default.
• W3009219785 cites W2078754671 @default.
• W3009219785 cites W2081808910 @default.
• W3009219785 cites W2110177543 @default.
• W3009219785 cites W2234721343 @default.
• W3009219785 cites W2323493158 @default.
• W3009219785 cites W2429651430 @default.
• W3009219785 cites W2478720077 @default.
• W3009219785 cites W2545777835 @default.
• W3009219785 cites W2580996365 @default.
• W3009219785 cites W2965174296 @default.
• W3009219785 cites W3100549810 @default.
• W3009219785 cites W4247151573 @default.
• W3009219785 cites W985078251 @default.
• W3009219785 doi "https://doi.org/10.3390/biom10030413" @default.
• W3009219785 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7175343" @default.
• W3009219785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32155964" @default.
• W3009219785 hasPublicationYear "2020" @default.
• W3009219785 type Work @default.
• W3009219785 sameAs 3009219785 @default.
• W3009219785 citedByCount "9" @default.
• W3009219785 countsByYear W30092197852020 @default.
• W3009219785 countsByYear W30092197852021 @default.
• W3009219785 countsByYear W30092197852022 @default.
• W3009219785 countsByYear W30092197852023 @default.
• W3009219785 crossrefType "journal-article" @default.
• W3009219785 hasAuthorship W3009219785A5029272165 @default.
• W3009219785 hasAuthorship W3009219785A5077671600 @default.
• W3009219785 hasAuthorship W3009219785A5085372653 @default.
• W3009219785 hasAuthorship W3009219785A5085509801 @default.
• W3009219785 hasBestOaLocation W30092197851 @default.
• W3009219785 hasConcept C12554922 @default.
• W3009219785 hasConcept C127413603 @default.
• W3009219785 hasConcept C150394285 @default.
• W3009219785 hasConcept C155672457 @default.
• W3009219785 hasConcept C159985019 @default.
• W3009219785 hasConcept C171250308 @default.
• W3009219785 hasConcept C178790620 @default.
• W3009219785 hasConcept C185592680 @default.
• W3009219785 hasConcept C192562407 @default.
• W3009219785 hasConcept C2777803738 @default.
• W3009219785 hasConcept C2778414984 @default.
• W3009219785 hasConcept C2779036427 @default.
• W3009219785 hasConcept C32909587 @default.
• W3009219785 hasConcept C42360764 @default.
• W3009219785 hasConcept C55493867 @default.
• W3009219785 hasConcept C84416704 @default.
• W3009219785 hasConcept C86803240 @default.
• W3009219785 hasConcept C88001094 @default.
• W3009219785 hasConceptScore W3009219785C12554922 @default.
• W3009219785 hasConceptScore W3009219785C127413603 @default.
• W3009219785 hasConceptScore W3009219785C150394285 @default.
• W3009219785 hasConceptScore W3009219785C155672457 @default.
• W3009219785 hasConceptScore W3009219785C159985019 @default.
• W3009219785 hasConceptScore W3009219785C171250308 @default.
• W3009219785 hasConceptScore W3009219785C178790620 @default.
• W3009219785 hasConceptScore W3009219785C185592680 @default.
• W3009219785 hasConceptScore W3009219785C192562407 @default.
• W3009219785 hasConceptScore W3009219785C2777803738 @default.
• W3009219785 hasConceptScore W3009219785C2778414984 @default.
• W3009219785 hasConceptScore W3009219785C2779036427 @default.
• W3009219785 hasConceptScore W3009219785C32909587 @default.
• W3009219785 hasConceptScore W3009219785C42360764 @default.
• W3009219785 hasConceptScore W3009219785C55493867 @default.
• W3009219785 hasConceptScore W3009219785C84416704 @default.
• W3009219785 hasConceptScore W3009219785C86803240 @default.

• next