Matches in SemOpenAlex for { <https://semopenalex.org/work/W3009603149> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W3009603149 abstract "Introduction Nonalcoholic fatty liver disease (NAFLD) is an independent risk factor for coronary artery disease; moreover, it increases systemic atherosclerotic burden by inducing the overexpression of inflammatory mediators, promoting endothelial damage, and impairing blood pressure regulation. Aim Aim of this work was to evaluate whether a standardized evaluation of NAFLD improves cardiovascular risk assessment recognizing subclinical atherosclerosis in lower cardiovascular risk. Material and methods We investigated NAFLD occurrence and severity, carotid and femoral intima-media-thickness (IMT) and vascular stiffness by ultrasound technique, endothelial function by peripheral-arterial-tonometry, lipid profile and inflammatory markers in 220 subjects (100 men, 120 women; 45.42 ± 13.22 years old), without history of cardiovascular event, diabetes, liver infection, alcohol consumption, systemic diseases, and the use of drugs causing liver damage. NAFLD was evaluated, graded according to an eight-point scoring semi-quantitative severity score. Results and discussion At univariate logistic analysis, NAFLD ≥ 3 score was significantly associated with pathological IMT, augmentation index, pulsewave-velocity at carotids and femoral arteries, and endothelial dysfunction, and this association was confirmed after adjustment for European Society of Cardiology Systematic Coronary Risk Evaluation (ESC SCORE) at multivariate analyses. Moreover, high sensitivity C-reactive protein levels were significantly higher in patients with at least 3 point steatosis, in comparison to the others. Receiver operating characteristic (ROC) curve analysis for NAFLD showed a significant higher area under curve for the detection of both early atherosclerotic burden and vascular stiffness, in comparison to ROC curve of ESC SCORE. Conclusions According to our findings a NAFLD ≥ 3 score was able to screen a subgroup with widespread morphological vascular damage and endothelial dysfunction in a primary prevention population." @default.
- W3009603149 created "2020-03-13" @default.
- W3009603149 creator A5031346703 @default.
- W3009603149 creator A5041788136 @default.
- W3009603149 creator A5070057174 @default.
- W3009603149 creator A5086012384 @default.
- W3009603149 date "2020-01-01" @default.
- W3009603149 modified "2023-09-25" @default.
- W3009603149 title "Semi-quantitative ultrasound assessment of nonalcoholic fatty liver disease highlightens early subclinical atherosclerotic vascular damage: From risk factors to vascular damage" @default.
- W3009603149 doi "https://doi.org/10.29089/2020.20.00094" @default.
- W3009603149 hasPublicationYear "2020" @default.
- W3009603149 type Work @default.
- W3009603149 sameAs 3009603149 @default.
- W3009603149 citedByCount "0" @default.
- W3009603149 crossrefType "journal-article" @default.
- W3009603149 hasAuthorship W3009603149A5031346703 @default.
- W3009603149 hasAuthorship W3009603149A5041788136 @default.
- W3009603149 hasAuthorship W3009603149A5070057174 @default.
- W3009603149 hasAuthorship W3009603149A5086012384 @default.
- W3009603149 hasBestOaLocation W30096031491 @default.
- W3009603149 hasConcept C113280763 @default.
- W3009603149 hasConcept C11783203 @default.
- W3009603149 hasConcept C126322002 @default.
- W3009603149 hasConcept C134018914 @default.
- W3009603149 hasConcept C164705383 @default.
- W3009603149 hasConcept C2775850156 @default.
- W3009603149 hasConcept C2776175330 @default.
- W3009603149 hasConcept C2776954865 @default.
- W3009603149 hasConcept C2778213512 @default.
- W3009603149 hasConcept C2778772119 @default.
- W3009603149 hasConcept C2779134260 @default.
- W3009603149 hasConcept C2779339615 @default.
- W3009603149 hasConcept C2780972559 @default.
- W3009603149 hasConcept C2987047532 @default.
- W3009603149 hasConcept C555293320 @default.
- W3009603149 hasConcept C58471807 @default.
- W3009603149 hasConcept C71924100 @default.
- W3009603149 hasConcept C76318530 @default.
- W3009603149 hasConcept C84393581 @default.
- W3009603149 hasConcept C90924648 @default.
- W3009603149 hasConceptScore W3009603149C113280763 @default.
- W3009603149 hasConceptScore W3009603149C11783203 @default.
- W3009603149 hasConceptScore W3009603149C126322002 @default.
- W3009603149 hasConceptScore W3009603149C134018914 @default.
- W3009603149 hasConceptScore W3009603149C164705383 @default.
- W3009603149 hasConceptScore W3009603149C2775850156 @default.
- W3009603149 hasConceptScore W3009603149C2776175330 @default.
- W3009603149 hasConceptScore W3009603149C2776954865 @default.
- W3009603149 hasConceptScore W3009603149C2778213512 @default.
- W3009603149 hasConceptScore W3009603149C2778772119 @default.
- W3009603149 hasConceptScore W3009603149C2779134260 @default.
- W3009603149 hasConceptScore W3009603149C2779339615 @default.
- W3009603149 hasConceptScore W3009603149C2780972559 @default.
- W3009603149 hasConceptScore W3009603149C2987047532 @default.
- W3009603149 hasConceptScore W3009603149C555293320 @default.
- W3009603149 hasConceptScore W3009603149C58471807 @default.
- W3009603149 hasConceptScore W3009603149C71924100 @default.
- W3009603149 hasConceptScore W3009603149C76318530 @default.
- W3009603149 hasConceptScore W3009603149C84393581 @default.
- W3009603149 hasConceptScore W3009603149C90924648 @default.
- W3009603149 hasLocation W30096031491 @default.
- W3009603149 hasLocation W30096031492 @default.
- W3009603149 hasOpenAccess W3009603149 @default.
- W3009603149 hasPrimaryLocation W30096031491 @default.
- W3009603149 hasRelatedWork W10925083 @default.
- W3009603149 hasRelatedWork W15763465 @default.
- W3009603149 hasRelatedWork W17522492 @default.
- W3009603149 hasRelatedWork W19889141 @default.
- W3009603149 hasRelatedWork W3293242 @default.
- W3009603149 hasRelatedWork W4650811 @default.
- W3009603149 hasRelatedWork W5959792 @default.
- W3009603149 hasRelatedWork W701675 @default.
- W3009603149 hasRelatedWork W7924202 @default.
- W3009603149 hasRelatedWork W10958683 @default.
- W3009603149 isParatext "false" @default.
- W3009603149 isRetracted "false" @default.
- W3009603149 magId "3009603149" @default.
- W3009603149 workType "article" @default.