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• W3009805930 abstract "In recent years, printed circuit board (PCB)-based microfluidics have been explored as a means to achieve standardization, seamless integration, and large-scale manufacturing of microfluidics, thus paving the way for widespread commercialization of developed prototypes. In this work, static micro polymerase chain reaction (microPCR) devices comprising resistive microheaters integrated on PCBs are introduced as miniaturized thermocyclers for efficient DNA amplification. Their performance is compared to that of conventional thermocyclers, in terms of amplification efficiency, power consumption and duration. Exhibiting similar efficiency to conventional thermocyclers, PCB-based miniaturized thermocycling achieves faster DNA amplification, with significantly smaller power consumption. Simulations guide the design of such devices and propose means for further improvement of their performance." @default.
• W3009805930 created "2020-03-13" @default.
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• W3009805930 date "2020-02-28" @default.
• W3009805930 modified "2023-10-03" @default.
• W3009805930 title "Towards PCB-Based Miniaturized Thermocyclers for DNA Amplification" @default.
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• W3009805930 doi "https://doi.org/10.3390/mi11030258" @default.
• W3009805930 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7143664" @default.
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