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- W3010004073 abstract "Abstract The different oxidation states of sulphur atom play a significant role on functional materials. In this work, a aryl-thioether and its sulphone substituted benzo[c][1,2,5]oxadiazole dyes were synthesized and utilized to determine thiol-containing amino acids. The result of selectivity experiments showed they detected the cysteine and homocysteine under physiological condition with negligible interference from other amino acids. In comparison to the thioether dye, the sulphone-based dye exhibited much faster response time for Cys and Hcy. However, the sulphone restricted its thiol-reactivity and bioimaging performance in living cells. By reducing the oxidation state of sulphur atom, we amazedly found that the sulfoxide-based dye still maintained high selectivity ultrafast response time for Cys/Hcy under physiological condition. It was worth mentioning that it also had high reactivity and good bioimaging performance that sulfone compounds did not have." @default.
- W3010004073 created "2020-03-13" @default.
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- W3010004073 date "2020-11-01" @default.
- W3010004073 modified "2023-09-23" @default.
- W3010004073 title "The regulation of biothiol-responsive performance and bioimaging application of benzo[c][1,2,5]oxadiazole dyes" @default.
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- W3010004073 doi "https://doi.org/10.1016/j.cclet.2020.02.047" @default.
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