FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3010052010> ?p ?o ?g. }

• W3010052010 endingPage "e0229696" @default.
• W3010052010 startingPage "e0229696" @default.
• W3010052010 abstract "Background & aim In clinical practice, transarterial chemoembolization (TACE) has been widely used for the treatment of hepatocellular carcinoma (HCC) beyond as well as within guideline recommendations. Here we aimed to verify whether two consecutive non-responses could be an optimal criterion for creating a rule to stop TACE being performed on these patients. Methods This study evaluated 200 patients with HCC beyond the Milan criteria, initially treated with TACE. TACE response was determined using the mRECIST criteria via dynamic CT or MRI. Median follow-up duration was 23.9 months. Results Within the 200 patients analyzed, 183 (91.5%) were male, with a total median age of 59.8 years. The mean size of the largest tumor was 6.8 cm, with 80 (40.0%) patients with ≥4 tumors. After the first TACE procedure, complete response, partial response, stable disease, or progressive disease were observed in 48 (24.0%), 87 (43.5%), 59 (29.5%) and 6 (3.0%) of patients, respectively. 45 (22.5%) patients showed no objective response (OR) following two consecutive TACE sessions. Of these, 28 received a subsequent TACE, with a 10.7% OR rate. Patients without OR showed poorer survival when compared to patients who achieved OR after repeated TACE. Multivariable analysis showed that size of the largest tumor >5cm and high alpha-fetoprotein of >200 ng/mL were significant factors associated with failure of OR to two consecutive TACE sessions. Conclusion Patients showing no OR to two consecutive TACE sessions will present a poor OR to subsequent TACE procedures. Early transition to systemic therapy may be advocated in such cases." @default.
• W3010052010 created "2020-03-13" @default.
• W3010052010 creator A5018105181 @default.
• W3010052010 creator A5027735596 @default.
• W3010052010 creator A5028493964 @default.
• W3010052010 creator A5040147082 @default.
• W3010052010 creator A5054823424 @default.
• W3010052010 creator A5066597203 @default.
• W3010052010 creator A5089499718 @default.
• W3010052010 date "2020-03-04" @default.
• W3010052010 modified "2023-10-18" @default.
• W3010052010 title "Evaluation of transarterial chemoembolization refractoriness in patients with hepatocellular carcinoma" @default.
• W3010052010 cites W1755620415 @default.
• W3010052010 cites W1857070662 @default.
• W3010052010 cites W1930892342 @default.
• W3010052010 cites W1967541992 @default.
• W3010052010 cites W1971837077 @default.
• W3010052010 cites W1975154077 @default.
• W3010052010 cites W2009257495 @default.
• W3010052010 cites W2028319026 @default.
• W3010052010 cites W2052552898 @default.
• W3010052010 cites W2055985600 @default.
• W3010052010 cites W2079586464 @default.
• W3010052010 cites W2089762998 @default.
• W3010052010 cites W2104414799 @default.
• W3010052010 cites W2125763116 @default.
• W3010052010 cites W2149308948 @default.
• W3010052010 cites W2226763652 @default.
• W3010052010 cites W2277004004 @default.
• W3010052010 cites W2278888725 @default.
• W3010052010 cites W2286222994 @default.
• W3010052010 cites W2468187509 @default.
• W3010052010 cites W2582878252 @default.
• W3010052010 cites W2623680006 @default.
• W3010052010 cites W2625856057 @default.
• W3010052010 cites W2766884079 @default.
• W3010052010 cites W2793119715 @default.
• W3010052010 doi "https://doi.org/10.1371/journal.pone.0229696" @default.
• W3010052010 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7055892" @default.
• W3010052010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32130270" @default.
• W3010052010 hasPublicationYear "2020" @default.
• W3010052010 type Work @default.
• W3010052010 sameAs 3010052010 @default.
• W3010052010 citedByCount "16" @default.
• W3010052010 countsByYear W30100520102020 @default.
• W3010052010 countsByYear W30100520102021 @default.
• W3010052010 countsByYear W30100520102022 @default.
• W3010052010 countsByYear W30100520102023 @default.
• W3010052010 crossrefType "journal-article" @default.
• W3010052010 hasAuthorship W3010052010A5018105181 @default.
• W3010052010 hasAuthorship W3010052010A5027735596 @default.
• W3010052010 hasAuthorship W3010052010A5028493964 @default.
• W3010052010 hasAuthorship W3010052010A5040147082 @default.
• W3010052010 hasAuthorship W3010052010A5054823424 @default.
• W3010052010 hasAuthorship W3010052010A5066597203 @default.
• W3010052010 hasAuthorship W3010052010A5089499718 @default.
• W3010052010 hasBestOaLocation W30100520101 @default.
• W3010052010 hasConcept C121332964 @default.
• W3010052010 hasConcept C126322002 @default.
• W3010052010 hasConcept C142424586 @default.
• W3010052010 hasConcept C142724271 @default.
• W3010052010 hasConcept C2778019345 @default.
• W3010052010 hasConcept C2778822529 @default.
• W3010052010 hasConcept C2779134260 @default.
• W3010052010 hasConcept C2779984678 @default.
• W3010052010 hasConcept C2780182762 @default.
• W3010052010 hasConcept C70616116 @default.
• W3010052010 hasConcept C71924100 @default.
• W3010052010 hasConcept C87355193 @default.
• W3010052010 hasConcept C90924648 @default.
• W3010052010 hasConceptScore W3010052010C121332964 @default.
• W3010052010 hasConceptScore W3010052010C126322002 @default.
• W3010052010 hasConceptScore W3010052010C142424586 @default.
• W3010052010 hasConceptScore W3010052010C142724271 @default.
• W3010052010 hasConceptScore W3010052010C2778019345 @default.
• W3010052010 hasConceptScore W3010052010C2778822529 @default.
• W3010052010 hasConceptScore W3010052010C2779134260 @default.
• W3010052010 hasConceptScore W3010052010C2779984678 @default.
• W3010052010 hasConceptScore W3010052010C2780182762 @default.
• W3010052010 hasConceptScore W3010052010C70616116 @default.
• W3010052010 hasConceptScore W3010052010C71924100 @default.
• W3010052010 hasConceptScore W3010052010C87355193 @default.
• W3010052010 hasConceptScore W3010052010C90924648 @default.
• W3010052010 hasFunder F4320320303 @default.
• W3010052010 hasIssue "3" @default.
• W3010052010 hasLocation W30100520101 @default.
• W3010052010 hasLocation W30100520102 @default.
• W3010052010 hasLocation W30100520103 @default.
• W3010052010 hasLocation W30100520104 @default.
• W3010052010 hasLocation W30100520105 @default.
• W3010052010 hasOpenAccess W3010052010 @default.
• W3010052010 hasPrimaryLocation W30100520101 @default.
• W3010052010 hasRelatedWork W1591915866 @default.
• W3010052010 hasRelatedWork W2274256753 @default.
• W3010052010 hasRelatedWork W2342166145 @default.
• W3010052010 hasRelatedWork W2913583221 @default.
• W3010052010 hasRelatedWork W2945320998 @default.
• W3010052010 hasRelatedWork W3010052010 @default.

• next