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- W3010180298 endingPage "110057" @default.
- W3010180298 startingPage "110057" @default.
- W3010180298 abstract "Platinum-based chemotherapy remains the cornerstone of treatment for many malignancies. However, although therapeutic efficiency varies greatly among individuals, there is a lack of pharmacogenomic biomarkers that can be used in clinical settings to identify chemosensitive patients and allow stratification. With the development of high-throughput screening techniques and systems biology approaches, a growing body of evidence has shown that platinum resistance is a multifactorial, multi-dimensional, dynamic process incorporating genetic background, tumor evolution and gut microbes. This review critically summarizes potential pharmacogenomic biomarkers for predicting the efficacy of platinum drugs and provides a comprehensive, time-varying perspective that integrates multiple markers." @default.
- W3010180298 created "2020-03-13" @default.
- W3010180298 creator A5002608004 @default.
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- W3010180298 creator A5040090704 @default.
- W3010180298 creator A5041152040 @default.
- W3010180298 creator A5043288485 @default.
- W3010180298 date "2020-06-01" @default.
- W3010180298 modified "2023-10-14" @default.
- W3010180298 title "Pharmacogenomics for the efficacy of platinum-based chemotherapy: Old drugs, new integrated perspective" @default.
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