Matches in SemOpenAlex for { <https://semopenalex.org/work/W3010249518> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W3010249518 endingPage "104612" @default.
- W3010249518 startingPage "104612" @default.
- W3010249518 abstract "Free jejunal flap for circumferential pharyngeal reconstruction is associated with late-onset dysphagia, regurgitation and prolonged transit time. This study aims to assess the feasibility and efficacy of Botulinum toxin A (Botox) in alleviating such swallowing dysfunction. Twenty-six consecutive patients underwent free jejunal flap for circumferential pharyngeal reconstruction between January 2012 and December 2018. Outcomes were compared at 6, 12 and 24 months. In the non-Botox group (n = 13), video-fluoroscopic and manometry studies demonstrated asynchronous contractions and retrograde propulsion. All patients complained of nasal regurgitation on thin fluids at 6, 12 and 24 months. Bolus residue accumulation along jejunal mucosal folds resulted in prolonged transit time. In the Botox group (n = 13), amplitude of asynchronous contractions were lower: 25.4 mmHg vs. 52.1 mmHg (p = 0.037) for thin fluids at 12 months. Three patients complained of nasal regurgitation on thin fluids at 6 months. All 3 were asymptomatic at 12 months. Transit time was shortened overall. Functional Oral Intake Scale was higher. MD Anderson Dysphagia Inventory global (72.5% vs 45.7%, p = 0.003) and functional (62.0% vs 40.6%, p = 0.012) subscales were significantly improved at 24 months. Botox safely and effectively alleviates swallowing dysfunction associated with free jejunal flap for circumferential pharyngeal reconstruction." @default.
- W3010249518 created "2020-03-13" @default.
- W3010249518 creator A5012697645 @default.
- W3010249518 creator A5030905743 @default.
- W3010249518 creator A5054552637 @default.
- W3010249518 creator A5083110733 @default.
- W3010249518 date "2020-05-01" @default.
- W3010249518 modified "2023-10-01" @default.
- W3010249518 title "Swallowing disorders following free jejunal flap reconstruction of circumferential pharyngeal defect: Does Botox help?" @default.
- W3010249518 cites W1589615011 @default.
- W3010249518 cites W1973033355 @default.
- W3010249518 cites W1974584320 @default.
- W3010249518 cites W1978072630 @default.
- W3010249518 cites W1985123910 @default.
- W3010249518 cites W1996012417 @default.
- W3010249518 cites W2010565802 @default.
- W3010249518 cites W2012065288 @default.
- W3010249518 cites W2023271645 @default.
- W3010249518 cites W2041013963 @default.
- W3010249518 cites W2059628287 @default.
- W3010249518 cites W2071751996 @default.
- W3010249518 cites W2081370895 @default.
- W3010249518 cites W2128497892 @default.
- W3010249518 cites W2139778668 @default.
- W3010249518 cites W2154488383 @default.
- W3010249518 cites W2334197230 @default.
- W3010249518 cites W2410268839 @default.
- W3010249518 cites W2736590291 @default.
- W3010249518 cites W2955644037 @default.
- W3010249518 doi "https://doi.org/10.1016/j.oraloncology.2020.104612" @default.
- W3010249518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32135435" @default.
- W3010249518 hasPublicationYear "2020" @default.
- W3010249518 type Work @default.
- W3010249518 sameAs 3010249518 @default.
- W3010249518 citedByCount "0" @default.
- W3010249518 crossrefType "journal-article" @default.
- W3010249518 hasAuthorship W3010249518A5012697645 @default.
- W3010249518 hasAuthorship W3010249518A5030905743 @default.
- W3010249518 hasAuthorship W3010249518A5054552637 @default.
- W3010249518 hasAuthorship W3010249518A5083110733 @default.
- W3010249518 hasConcept C112497637 @default.
- W3010249518 hasConcept C126322002 @default.
- W3010249518 hasConcept C141071460 @default.
- W3010249518 hasConcept C2776752453 @default.
- W3010249518 hasConcept C2777910003 @default.
- W3010249518 hasConcept C2780168065 @default.
- W3010249518 hasConcept C2780596822 @default.
- W3010249518 hasConcept C42219234 @default.
- W3010249518 hasConcept C43376680 @default.
- W3010249518 hasConcept C71924100 @default.
- W3010249518 hasConceptScore W3010249518C112497637 @default.
- W3010249518 hasConceptScore W3010249518C126322002 @default.
- W3010249518 hasConceptScore W3010249518C141071460 @default.
- W3010249518 hasConceptScore W3010249518C2776752453 @default.
- W3010249518 hasConceptScore W3010249518C2777910003 @default.
- W3010249518 hasConceptScore W3010249518C2780168065 @default.
- W3010249518 hasConceptScore W3010249518C2780596822 @default.
- W3010249518 hasConceptScore W3010249518C42219234 @default.
- W3010249518 hasConceptScore W3010249518C43376680 @default.
- W3010249518 hasConceptScore W3010249518C71924100 @default.
- W3010249518 hasLocation W30102495181 @default.
- W3010249518 hasOpenAccess W3010249518 @default.
- W3010249518 hasPrimaryLocation W30102495181 @default.
- W3010249518 hasRelatedWork W1978791062 @default.
- W3010249518 hasRelatedWork W1991368220 @default.
- W3010249518 hasRelatedWork W2032932644 @default.
- W3010249518 hasRelatedWork W2063661469 @default.
- W3010249518 hasRelatedWork W2090489504 @default.
- W3010249518 hasRelatedWork W2097398216 @default.
- W3010249518 hasRelatedWork W2098328320 @default.
- W3010249518 hasRelatedWork W2122016269 @default.
- W3010249518 hasRelatedWork W2922449716 @default.
- W3010249518 hasRelatedWork W3038019027 @default.
- W3010249518 hasVolume "104" @default.
- W3010249518 isParatext "false" @default.
- W3010249518 isRetracted "false" @default.
- W3010249518 magId "3010249518" @default.
- W3010249518 workType "article" @default.