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• W3010352714 abstract "Abstract Fatigue related to Multiple Sclerosis (MS) is considered a multidimensional symptom, manifesting in several dimensions such as physical, cognitive, and psychosocial fatigue. This study investigated in 264 patients with severe primary MS-related fatigue (median MS duration 6.8 years, mean age 48.1 years, 75% women) whether subgroups can be distinguished based on these dimensions. Subsequently, we tested whether MS-related fatigue consists of a single common unidimensional factor. Subscale scores on four self-reported fatigue questionnaires, including the Checklist of Individual Strength, the Modified Fatigue Impact Scale, the Fatigue Severity Scale and the SF36 vitality, were used in a cluster analysis to identify patients with similar fatigue characteristics. Next, all 54 items were included in exploratory factor analysis to test unidimensionality. Study results show that in patients with a treatment indication for primary MS-related fatigue, fatigue profiles are based on severity and not on the various dimensions of fatigue. The three profiles found, suggested one underlying fatigue dimension, but this could not be confirmed. Factor analysis of all 54 items resulted in 8 factors, confirming the multidimensional construct of the included fatigue questionnaires." @default.
• W3010352714 created "2020-03-13" @default.
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• W3010352714 date "2020-03-05" @default.
• W3010352714 modified "2023-10-15" @default.
• W3010352714 title "Fatigue Profiles in Patients with Multiple Sclerosis are Based on Severity of Fatigue and not on Dimensions of Fatigue" @default.
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• W3010352714 doi "https://doi.org/10.1038/s41598-020-61076-1" @default.
• W3010352714 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7058058" @default.
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• W3010352714 hasPublicationYear "2020" @default.
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