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- W301054182 abstract "Objective To evaluate the expression of the GLUT-1 glucose transporter in borderline and malignant epithelial neoplasms of the ovary. Methods Histologic sections of tumor tissues from 100 epithelial neoplasms of the ovary were stained for GLUT-1 using polyclonal GLUT-1 antibody and the labeled streptavidin procedure. Chi-square analysis was used to assess if their expression was associated with clinicopathoiogic characteristics of the tumors. Results Normal ovarian surface epithelial cell were either negative or weakly positive. The intensity of the stain was significantly stronger in malignant than borderline tumors (P<0.001). In malignant neoplasms, the intensity of the stain for GLUT-1 increased with histology. Conclusion Overexpression of the GLUT-1 transporter is associated with the histology and grade of the minors. These data suggest that the expression of this transporter may be closely related to the malignant transformation of epithelial ovarian tumors.Key words: Glucose transport proteins, facilitative; Ovarian neoplasms; Neoplasms, cystic, mucinous and serous" @default.
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- W301054182 date "2009-01-28" @default.
- W301054182 modified "2023-10-02" @default.
- W301054182 title "Expression of GLUT-1 glucose transporter in epithelial tumors of the ovary" @default.
- W301054182 doi "https://doi.org/10.3760/cma.j.issn.1006-9801.2009.01.012" @default.
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