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- W3010767401 abstract "Although synthetic amphiphiles that form ion-conducting pores have surged in interest within the chemical community, their potential as antimicrobials is little appreciated. The formation of pores in bacterial membranes has at least two obvious consequences. First, insertion of the amphiphile into the bacterial membrane results in membrane disruption or disorganization, enhancing membrane permeability. Second, to the extent that ion-conducting pores form within the membranes, ion homeostasis is likely to be affected. Changes in ion balance will have secondary effects on cytosolic proteins that may adversely affect bacterial survival." @default.
- W3010767401 created "2020-03-23" @default.
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- W3010767401 date "2020-06-01" @default.
- W3010767401 modified "2023-10-02" @default.
- W3010767401 title "Supramolecular pore formation as an antimicrobial strategy" @default.
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- W3010767401 doi "https://doi.org/10.1016/j.ccr.2020.213264" @default.
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