FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3010779551> ?p ?o ?g. }

• W3010779551 endingPage "12" @default.
• W3010779551 startingPage "1" @default.
• W3010779551 abstract "Lung cancer remains the most common cancer in the world. The genetic polymorphisms (rs2853669 in TERT, rs1052133 in OGG1, and rs16969968 in CHRNA5 genes) were shown to be strongly associated with the risk of lung cancer. Our study’s aim is to elucidate whether these polymorphisms predispose Eastern Algerian population to non-small-cell lung cancer (NSCLC). To date, no study has considered this association in the Algerian population. This study included 211 healthy individuals and 144 NSCLC cases. Genotyping was performed using TaqMan probes and Sanger sequencing, and the data were analyzed using multivariate logistic regression adjusted for covariates. The minor allele frequencies (MAFs) of TERT rs2853669, CHRNA5 rs16969968, and OGG1 rs1052133 polymorphisms in controls were C: 20%, A: 31%, and G: 29%, respectively. Of the three polymorphisms, none shows a significant association, but stratified analysis rs16969968 showed that persons carrying the AA genotype are significantly associated with adenocarcinoma risk (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mtext>pAdj</mml:mtext><mml:mo>=</mml:mo><mml:mn>0.03</mml:mn></mml:math>,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mtext>ORAdj</mml:mtext><mml:mo>=</mml:mo><mml:mn>2.55</mml:mn></mml:math>). Smokers with an AA allele have a larger risk of lung cancer than smokers with GG or GA genotype (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mtext>pAdj</mml:mtext><mml:mo>=</mml:mo><mml:mn>0.03</mml:mn></mml:math>,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mtext>ORAdj</mml:mtext><mml:mo>=</mml:mo><mml:mn>3.91</mml:mn></mml:math>), which is not the case of nonsmokers. Our study suggests that CHRNA5 rs16969968 polymorphism is associated with a significant increase of lung adenocarcinoma risk and with a nicotinic addiction." @default.
• W3010779551 created "2020-03-23" @default.
• W3010779551 creator A5001536864 @default.
• W3010779551 creator A5008951518 @default.
• W3010779551 creator A5010035230 @default.
• W3010779551 creator A5022517715 @default.
• W3010779551 creator A5024486993 @default.
• W3010779551 creator A5026875727 @default.
• W3010779551 creator A5028264442 @default.
• W3010779551 creator A5031593706 @default.
• W3010779551 creator A5033112013 @default.
• W3010779551 creator A5036124398 @default.
• W3010779551 creator A5053473327 @default.
• W3010779551 creator A5057987159 @default.
• W3010779551 creator A5065990046 @default.
• W3010779551 creator A5071654666 @default.
• W3010779551 creator A5079062625 @default.
• W3010779551 creator A5087607494 @default.
• W3010779551 creator A5090177578 @default.
• W3010779551 creator A5090486885 @default.
• W3010779551 date "2020-03-20" @default.
• W3010779551 modified "2023-10-01" @default.
• W3010779551 title "Association of TERT, OGG1, and CHRNA5 Polymorphisms and the Predisposition to Lung Cancer in Eastern Algeria" @default.
• W3010779551 cites W1576436685 @default.
• W3010779551 cites W1968727716 @default.
• W3010779551 cites W1970854641 @default.
• W3010779551 cites W1972020976 @default.
• W3010779551 cites W1975905059 @default.
• W3010779551 cites W1986333129 @default.
• W3010779551 cites W1988731792 @default.
• W3010779551 cites W1995703314 @default.
• W3010779551 cites W2002793133 @default.
• W3010779551 cites W2028289620 @default.
• W3010779551 cites W2029687074 @default.
• W3010779551 cites W2043471050 @default.
• W3010779551 cites W2043531700 @default.
• W3010779551 cites W2055481234 @default.
• W3010779551 cites W2063776149 @default.
• W3010779551 cites W2073806145 @default.
• W3010779551 cites W2079179101 @default.
• W3010779551 cites W2085301101 @default.
• W3010779551 cites W2087031098 @default.
• W3010779551 cites W2090926117 @default.
• W3010779551 cites W2091077612 @default.
• W3010779551 cites W2098245252 @default.
• W3010779551 cites W2101876919 @default.
• W3010779551 cites W2102775530 @default.
• W3010779551 cites W2110931187 @default.
• W3010779551 cites W2112488127 @default.
• W3010779551 cites W2118082971 @default.
• W3010779551 cites W2119415736 @default.
• W3010779551 cites W2120240963 @default.
• W3010779551 cites W2128306943 @default.
• W3010779551 cites W2129511844 @default.
• W3010779551 cites W2131602976 @default.
• W3010779551 cites W2137667379 @default.
• W3010779551 cites W2141042406 @default.
• W3010779551 cites W2154040364 @default.
• W3010779551 cites W2161636044 @default.
• W3010779551 cites W2166014789 @default.
• W3010779551 cites W2168036807 @default.
• W3010779551 cites W2173848837 @default.
• W3010779551 cites W2233089496 @default.
• W3010779551 cites W2251424345 @default.
• W3010779551 cites W2346842253 @default.
• W3010779551 cites W257987643 @default.
• W3010779551 cites W2587764188 @default.
• W3010779551 cites W2765783610 @default.
• W3010779551 cites W2790631564 @default.
• W3010779551 cites W2802754043 @default.
• W3010779551 cites W2827572209 @default.
• W3010779551 cites W2894644751 @default.
• W3010779551 cites W2895926103 @default.
• W3010779551 doi "https://doi.org/10.1155/2020/7649038" @default.
• W3010779551 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7109590" @default.
• W3010779551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32257438" @default.
• W3010779551 hasPublicationYear "2020" @default.
• W3010779551 type Work @default.
• W3010779551 sameAs 3010779551 @default.
• W3010779551 citedByCount "3" @default.
• W3010779551 countsByYear W30107795512020 @default.
• W3010779551 countsByYear W30107795512021 @default.
• W3010779551 countsByYear W30107795512023 @default.
• W3010779551 crossrefType "journal-article" @default.
• W3010779551 hasAuthorship W3010779551A5001536864 @default.
• W3010779551 hasAuthorship W3010779551A5008951518 @default.
• W3010779551 hasAuthorship W3010779551A5010035230 @default.
• W3010779551 hasAuthorship W3010779551A5022517715 @default.
• W3010779551 hasAuthorship W3010779551A5024486993 @default.
• W3010779551 hasAuthorship W3010779551A5026875727 @default.
• W3010779551 hasAuthorship W3010779551A5028264442 @default.
• W3010779551 hasAuthorship W3010779551A5031593706 @default.
• W3010779551 hasAuthorship W3010779551A5033112013 @default.
• W3010779551 hasAuthorship W3010779551A5036124398 @default.
• W3010779551 hasAuthorship W3010779551A5053473327 @default.
• W3010779551 hasAuthorship W3010779551A5057987159 @default.
• W3010779551 hasAuthorship W3010779551A5065990046 @default.
• W3010779551 hasAuthorship W3010779551A5071654666 @default.

• next