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• W3010780031 abstract "To compare maternal and fetal outcomes of pregnancies complicated and not complicated with hyperemesis gravidarum (HG) necessitating hospitalization.A total of 386 women with singleton deliveries between March 2015 and January 2018 were included in this retrospective single-center study. Of 386 women, 186 women (mean±SD age: 30.7±5.9 years) who were hospitalized with HG within the first 20 weeks of gestation comprised the hyperemetic pregnancy group, while 200 women without HG during pregnancy served as a control group.No significant difference was noted between the HG and control groups in terms of maternal characteristics, gestational age (median 38.6 and 39.0 weeks, respectively), type of delivery (normal spontaneous delivery in 78.0% vs 80.0%), fetal gender (female: 53.2% vs 48.5%), birthweight (median 3250 g vs 3275 g) and 5-min APGAR scores (≥7 in 97.3% vs 97.5%, respectively). Adverse pregnancy outcomes were also similar between groups including preterm birth (8.1% vs 11.0%, respectively), SGA (5.9% vs 9.5%), hypertensive disorder (5.4% vs 7.5%), placental abruption (1.1% vs 0.5%,), stillbirth (0.0% vs 0.5%) and GDM (3.8%vs 2.5%). Weight loss during pregnancy was evident in 91.3% of women in the HG group, while none of women in the control group had weight loss during pregnancy (p<0.001).The findings of this study indicate that HG may not be related with adverse fetal and prenatal outcomes and this conclusion needs to be clarified with large-scale investigations.Hastaneye yatarak tedavi gerektiren hiperemezis gravidarum (HG) ile komplike gebelikler ile hiperemezis gravidarum görülmeyen gebeliklerin maternal ve fetal sonuçlarını karşılaştırmak.Tek merkezde yapılan bu retrospektif çalışmaya 2015 Mart ile 2018 Ocak arasında tekil doğum yapan 386 kadın dahil edildi. 386 kadının 186’sı (ortalama±SD yaş: 30,7±5,9 yıl) gebeliğin ilk 20 haftasında hiperemezis gravidarum nedeniyle hastaneye yatırılan kadınlardan oluşurken hiperemezis gravidarum görülmeyen 200 kadın kontrol grubu olarak oluşturdu.HG ve kontrol grupları arasında maternal özellikler, ve sırasıyla gebelik yaşı (ortalama 38,6 ve 39,0 hafta), doğum şekli (normal spontan doğum, %78,0 ve %80,0), fetal cinsiyet (kız, %53,2 ve %4,5), doğum ağırlığı (ortalama 3250 g ve 3275 g) ve 5 dk.’lık APGAR skorları (≥7, %97,3 ve %97,5) farklılık görülmedi. Olumsuz gebelik sonuçları olarak değerlendirilen preterm doğum (%8,1 ve %11,0), SGA (%5,9 ve %9,5), hipertansif hastalıklar (%5.4 ve %7.5), dekolman plasenta (%1,1 ve %0,5) ve GDM (%3,8 ve %2.5) görülme oranları da benzer bulundu. Gebelik sırasında kilo kaybı hiperemezis gravidarum grubundaki kadınların %91,3’ünde görülürken, kontrol grubundaki kadınların hiçbirinde gebelik sırasında kilo kaybı görülmedi (p<0.001).Bu çalışmanın bulguları, geniş ölçekli başka çalışmalarla doğrulanmak üzere, hiperemezis gravidarumun olumsuz fetal ve maternal komplikasyonlarla ilişkili olmayabileceğine işaret etmektedir." @default.
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• W3010780031 date "2020-01-01" @default.
• W3010780031 modified "2023-10-16" @default.
• W3010780031 title "Comparative Analysis of Maternal and Fetal Outcomes of Pregnancies Complicated and Not Complicated with Hyperemesis Gravidarum Necessitating Hospitalization" @default.
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• W3010780031 doi "https://doi.org/10.5222/mmj.2020.57767" @default.
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