Matches in SemOpenAlex for { <https://semopenalex.org/work/W3010803516> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3010803516 endingPage "432" @default.
- W3010803516 startingPage "427" @default.
- W3010803516 abstract "Abstract Ulipristal acetate (UPA) is used as emergency contraceptive and for uterine fibroids. No validated method has been reported to estimate UPA in presence of its degradation products. Therefore it is mandatory to develop method which can accurately measure it in presence of impurity. A simple and sensitive high-performance thin-layer chromatography (HPTLC) method was developed for the estimation of UPA. Pre-coated silica gel 60F254 TLC plates were as stationary phase and ethyl acetate:toluene:glacial acetic acid (4:7:0.3, v/v/v) was used as mobile phase. Drug was subjected to acid and alkali hydrolysis, oxidation, photo degradation and thermal degradation to study its degradation behavior. UPA eluted with Rf value 0.38 ± 0.02. The method was found to be linear in the concentration range of 400–3,600 ng/band. Limit of detection and limit of quantitation were found to be 72.7786 ng/band and 220.5412 ng/band, respectively. The % recovery of the proposed method was found to be 100.05–100.65%. The proposed method was specific to measure UPA in presence of degradants. The method was found to be accurate, precise, robust and can be useful for routine analysis of formulations containing UPA in presence of its degradation products." @default.
- W3010803516 created "2020-03-23" @default.
- W3010803516 creator A5000929935 @default.
- W3010803516 creator A5076670492 @default.
- W3010803516 date "2020-03-12" @default.
- W3010803516 modified "2023-09-25" @default.
- W3010803516 title "Optimization and Validation of HPTLC Method for Estimation of Ulipristal Acetate in Presence of Its Forced Degradation Products" @default.
- W3010803516 cites W2047797139 @default.
- W3010803516 cites W2085549493 @default.
- W3010803516 doi "https://doi.org/10.1093/chromsci/bmaa002" @default.
- W3010803516 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32163148" @default.
- W3010803516 hasPublicationYear "2020" @default.
- W3010803516 type Work @default.
- W3010803516 sameAs 3010803516 @default.
- W3010803516 citedByCount "0" @default.
- W3010803516 crossrefType "journal-article" @default.
- W3010803516 hasAuthorship W3010803516A5000929935 @default.
- W3010803516 hasAuthorship W3010803516A5076670492 @default.
- W3010803516 hasConcept C108454664 @default.
- W3010803516 hasConcept C119128265 @default.
- W3010803516 hasConcept C144024400 @default.
- W3010803516 hasConcept C149923435 @default.
- W3010803516 hasConcept C178790620 @default.
- W3010803516 hasConcept C185592680 @default.
- W3010803516 hasConcept C190196608 @default.
- W3010803516 hasConcept C23531484 @default.
- W3010803516 hasConcept C2776673659 @default.
- W3010803516 hasConcept C2777486506 @default.
- W3010803516 hasConcept C2777682752 @default.
- W3010803516 hasConcept C2778142098 @default.
- W3010803516 hasConcept C2779076696 @default.
- W3010803516 hasConcept C2779532046 @default.
- W3010803516 hasConcept C2779679103 @default.
- W3010803516 hasConcept C2779858419 @default.
- W3010803516 hasConcept C2908647359 @default.
- W3010803516 hasConcept C2986817661 @default.
- W3010803516 hasConcept C41008148 @default.
- W3010803516 hasConcept C43617362 @default.
- W3010803516 hasConcept C76155785 @default.
- W3010803516 hasConcept C90932021 @default.
- W3010803516 hasConcept C94412978 @default.
- W3010803516 hasConceptScore W3010803516C108454664 @default.
- W3010803516 hasConceptScore W3010803516C119128265 @default.
- W3010803516 hasConceptScore W3010803516C144024400 @default.
- W3010803516 hasConceptScore W3010803516C149923435 @default.
- W3010803516 hasConceptScore W3010803516C178790620 @default.
- W3010803516 hasConceptScore W3010803516C185592680 @default.
- W3010803516 hasConceptScore W3010803516C190196608 @default.
- W3010803516 hasConceptScore W3010803516C23531484 @default.
- W3010803516 hasConceptScore W3010803516C2776673659 @default.
- W3010803516 hasConceptScore W3010803516C2777486506 @default.
- W3010803516 hasConceptScore W3010803516C2777682752 @default.
- W3010803516 hasConceptScore W3010803516C2778142098 @default.
- W3010803516 hasConceptScore W3010803516C2779076696 @default.
- W3010803516 hasConceptScore W3010803516C2779532046 @default.
- W3010803516 hasConceptScore W3010803516C2779679103 @default.
- W3010803516 hasConceptScore W3010803516C2779858419 @default.
- W3010803516 hasConceptScore W3010803516C2908647359 @default.
- W3010803516 hasConceptScore W3010803516C2986817661 @default.
- W3010803516 hasConceptScore W3010803516C41008148 @default.
- W3010803516 hasConceptScore W3010803516C43617362 @default.
- W3010803516 hasConceptScore W3010803516C76155785 @default.
- W3010803516 hasConceptScore W3010803516C90932021 @default.
- W3010803516 hasConceptScore W3010803516C94412978 @default.
- W3010803516 hasIssue "5" @default.
- W3010803516 hasLocation W30108035161 @default.
- W3010803516 hasOpenAccess W3010803516 @default.
- W3010803516 hasPrimaryLocation W30108035161 @default.
- W3010803516 hasRelatedWork W1198443576 @default.
- W3010803516 hasRelatedWork W2025229523 @default.
- W3010803516 hasRelatedWork W2066922574 @default.
- W3010803516 hasRelatedWork W2077488809 @default.
- W3010803516 hasRelatedWork W2087083218 @default.
- W3010803516 hasRelatedWork W2134605895 @default.
- W3010803516 hasRelatedWork W2493013600 @default.
- W3010803516 hasRelatedWork W3008236077 @default.
- W3010803516 hasRelatedWork W3135347193 @default.
- W3010803516 hasRelatedWork W2187270338 @default.
- W3010803516 hasVolume "58" @default.
- W3010803516 isParatext "false" @default.
- W3010803516 isRetracted "false" @default.
- W3010803516 magId "3010803516" @default.
- W3010803516 workType "article" @default.